How To Inject Peptides

Injectable peptides are more potent and cost-effective than oral form. Here, I'll explain everything you need to know in order to inject peptides safely.

Bodybuilders and athletes worldwide have started to use peptides more frequently as their go-to recovery agent. While most advanced bodybuilders use injectable peptides, other athletes prefer to use them in oral form due to overall ease of use or because they are afraid of botching injections, despite their reduced bioavailability.

However, learning how to inject peptides properly is not as difficult as it seems and it will provide greater long-term benefits, both in terms of achieving athletic goals much faster as well as in saving money.

In this review, I’ll provide you with all the steps you need in order to inject peptides as safely as possible and ensure that you get the most out of their use.

Peptide Injections

The most commonly used form of peptides is injectable, but peptides are also available in capsules, tablets, and patches as well.

Some peptides may work systemically, which means they have the same effect in the body no matter how or where it is administered. However, there is considerable evidence that suggests that injectable forms of peptides have shown better efficacy than non-injectable forms.

If we track the route of capsules or tablets in the body, they need to travel all the way from the mouth to the GIT (gastrointestinal tract). Throughout this pathway, oral forms of intake are subjected to different enzymes that can potentially degrade them before they can carry out their function.

Due to the enzyme degradation and large molecular size, many peptides don’t penetrate well through the intestinal mucosa (1). All this accounts for the poor bioavailability of the oral forms of peptide drug therapy.

This isn’t the case, however, with injectable forms as they can be directly administered at the injection site or in very close proximity to the area where one expects maximum changes.

It is important to note that some of the peptides also mimic the action of hormones in the human body. Peptides like sermorelin, hexarelin, or ipamorelin are growth hormone secretagogues (GHS), which trigger the release of growth hormone (GH) in the human body.

Research suggests that hormonal therapies are more effective when they are administered via injections than oral administration (2).

While many surveys found that oral intake is easier and more user-friendly for many patients, it is important to keep in mind that these findings are heavily influenced by the fear of needles (3).

 

Peptide Injections For Bodybuilding

how to inject peptides

Before digging into the exact steps to follow while injecting peptides, I want to give you a brief overview of the most common benefits that peptides offer to bodybuilders.

Peptides like sermorelin and hexarelin enhance muscle growth by causing the development of new muscle fibers and stimulate rapid proliferation. The right dosage of these synthetic peptides causes an increment in lean muscle mass as well.

They also cut down excessive body fat, especially in the abdominal region.

TB-500 helps build endurance and stamina. It’s well known for helping bodybuilders and athletes reach their maximum performance very smoothly.

Perhaps, the most wanted benefit that peptides like sermorelin, ipamorelin, and hexarelin offer is the ability to recover effectively from all the injuries. These peptides trigger the proliferation of growth cells in the injured areas, which leads to the quick healing of wounds.

Where To Inject Peptides

Peptides can be injected in 3 main ways. You can either inject it intravenously, intramuscularly or subcutaneously.

The intravenous mode of injection is a bit complicated because it requires medical supervision. One would need to locate the vein and then inject the peptide therapy into it.

Intramuscular mode is a relatively easy way as it requires a direct injection deep into the muscles. This method leads to quicker absorption of peptide drug therapy into the bloodstream.

Perhaps, the most advisable and common practice is to inject peptides subcutaneously (4). It involves administering the peptide just under the skin. You should manage the subcutaneous injection in the abdominal region, near the stomach.

Note that if you use peptide therapy to manage your injury, you can inject the drug close to the injured site as well.

Needle Size For Intramuscular Injection

If you are considering the option of intramuscular injection, the ideal needle you should be using is a 22-25 gauge needle.

You will be able to find the 22-25 gauge needle and the syringe at any of your closest pharmacies. Make sure that the gauge needle and syringe are sealed at the time of your purchase.

How To Inject Peptides

Once you have decided on your dosage requirements, you can purchase the peptides from any of your trusted stores. I would personally recommend buying it from Science.bio, Swiss Chems or Behemoth Labz.

Step 1

You will receive a lyophilized form of peptide in the vial (glass container) along with bacteriostatic water. The first step will be to reconstitute the peptide in compliance with your dosage guidelines.

how to inject peptides

Add the bacteriostatic water (the example shown above is Bacteriostatic Water (BAC) 10ml sold by Swiss Chems)  very slowly into the vial via the dropper. Avoid dropping the water in such a way that touches the wall of the vial. Slowly adding water will give enough time for the water and peptide to mix well enough.

Step 2

Some peptide labels require you to dispose of the vial immediately after opening it. If you are planning to store the peptide, make sure to read the label thoroughly. This will help you store the peptide in specific conditions without losing the efficiency of the peptide.

Step 3

Once you have decided the location of your injection site, rub it with an alcohol swab.

Step 4

how to inject peptides
Disposable Sterile (25G-1IN/25mm) by SHAOTONG

Use the new syringe and a 22-25 gauge needle, and pinch the needle at 90 degrees. The reason for holding it at this angle is to make sure that no blood vessel is perforated while injecting.

Also, there is substantial evidence suggesting that injecting at 90 degrees is found to be relatively comforting for the patients. Besides, it maintains the efficacy and effectiveness of peptide drug therapy (5).

Step 5

Once you have administered the dosage, wipe the injection site with cotton but make sure not to press it too hard.

Step 6

Please dispose of the needle once you have used it. Use a new one next time you inject yourself with the drug therapy.

If you still feel a bit nervous while administering your dosage, I would suggest you ask for help from an expert for ease.

Best Injectable Peptides

Now that you know the accurate way to inject peptides, let’s just review some of the most common peptides that have attracted many users lately.

Sermorelin

Sermorelin acetate, a peptide constituting 29 amino acids, is a growth hormone-releasing hormone (GHRH). It stimulates the release of growth hormone (GH) from the anterior pituitary gland.

It is a peptide that stimulates muscle growth, causes effective healing of wounds, enhances cardiovascular health, and improves sleep quality.

Ipamorelin

Ipamorelin is a peptide made up of 5 amino acids. It also binds with receptors like (GHS-R1a), which triggers the release of growth hormone (GH).

Ipamorelin increases lean body mass and cuts down unwanted body fat. It repairs the muscle fibers effectively and is known to enhance the overall musculoskeletal system. Ipamorelin also restores circadian sleep rhythms.

Hexarelin

Hexarelin acetate, a synthetic peptide, belongs to the growth hormone secretagogue (GHS) class. It also stimulates the release of growth hormone (GH) by binding to specific receptors known as (GHS-R1a).

Hexarelin enhances muscle growth, improves cardiovascular functioning greatly, builds endurance, triggers fat loss, and makes the healing process quicker yet effective.

Take-Home Message

Choosing the right peptide and administering it by following the right approach can yield fruitful results within no time.

Make sure to follow each step cautiously to avoid any complications. Go through your dosage and cycling guidelines closely to avoid any overdosing.

If you are planning to go with a stack, make sure to choose the right one!

https://pubmed.ncbi.nlm.nih.gov/15984901/

https://pubmed.ncbi.nlm.nih.gov/17915406/

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2792531/

https://pubmed.ncbi.nlm.nih.gov/12238797/

Kartik Kumar Rathi

Kartik is a Doctor in training currently in his first year of medical school with the ultimate goal of becoming a successful cardiologist, he currently contributes to health blogs, research papers and also founded a social health startup to help educate others.

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