Best HGH Peptides for Muscle Growth

HGH or Peptide Therapy can be very successful in helping you lose fat and improve overall health. Let's look at the Best HGH Peptides and how to use them.

Whether it’s hormone therapy or trying to lose weight with Peptides, chances are you’re looking at Growth Hormone Releasing Hormones.

Before we get too scientific for an intro, various studies and articles show that Growth Hormone is the key to combat aging, and some athletes even use it to perform well into their 50s!

Unfortunately, these Peptides are a bitch to understand. Wanna know how to make the best of your somatotropic axis?

Pull up some chair and make sure your refridgerator has a stable temperature while we discuss the best HGH Peptides.

Warning: The content on and the information included in this article is intended for entertainment and informational purposes only. It is not intended nor implied to be a substitute for professional medical advice. Prior to buying anything, check that it is compliant where you live with your current government laws. We frequently mention research chemicals that are not made for human consumption. Therefore, before purchasing any product for personal use, consult with your doctor or healthcare provider first.

Key Takeaways

  • HGH Peptides will either mimic or increase the HGH produced by your Pituitary gland
  • Peptides are simply Amino Acids in a long chain
  • The best Peptides for Fat Loss and overall health are HGH, CJC-1295, and Ipamorelin
  • Peptides for muscle growth is not as effective as they are for losing body fat
  • The best way to use them is with a coach or a HRT Clinic

What Are The Best HGH Peptides?

Above all else, the best will always remain pure Human Growth Hormone (HGH). The first human to receive HGH therapy was back in 1956, and it actually had a bovine origin.

Old HGH used to be made from cadavers, however, the HGH on the market today is made synthetically. In order to get pure HGH, you would need to work through an HRT Clinic such as Evolve Telemed – and you would need to have a medical diagnosis in order to be prescribed HGH.

The best HGH peptides you can purchase online are Growth Hormone Releasing Peptides (GHRP) and Growth Hormone Releasing Hormones (GHRH).

Another great alternative would be a Growth Hormone Secretagogue, such as MK 677.

#1 Best Overall

CJC 1295 + Ipamorelin Stack

This is the quintessential combination for Growth Hormone secretion. CJC-1295 is a Growth Hormone Releasing Hormone while Ipamorelin is one of the Growth Hormone Releasing Peptides.

Some studies are showing that using a GHRH and GHRP together will yield better results [2].

As this will massively increase your endogenous Growth Hormone release, you can expect similar results to taking pure HGH. Benefits include weight loss, muscle growth, and better body composition, and various human studies found that people just feel better on HGH therapy.

This is a very common peptide stack and is going to result in a better life, and potentially, your desired physique.

Stack Overview

⭐️ Top Benefits: Increase in Lean Muscle Mass, Enhanced Endurance, Improved Fat Loss, Better Sleep Quality, Enhanced Recovery, Strengthening of Joints and Connective Tissue.
🧪 Form: Injectable.
💉 Typical Dosage: CJC-1295: 1000 mcg to 2000 mcg per week; Ipamorelin: 200 mcg to 300 mcg per day.
⌛️ Typical Cycle Duration: 8 to 12 weeks (60 to 90 days).
💰 Average Cost: Approximately $49 (Prices may vary depending on the supplier and product concentration).
✅ Availability: Easily available through various online peptide suppliers, but a prescription may be required in some regions.
❤️‍🩹 Side Effects and Dangers: Vertigo, Increased Body Temperature, Water Retention, Headaches, Injection Site Reactions, Increased Hunger, Lowered Blood Sugar Levels.
🔄 See before and after
➡️ Go to the Full review

#2 Best GHRH


Tesamorelin is a Peptide that is prescribed to individuals that have too much adipose tissue around their stomach, typically those who suffer from HIV.

Certain illnesses and lifestyle choices will store fat more around the abdomen, which is actually pretty unhealthy.

Losing weight will mostly be determined by training and diet, however, Tesamorelin combined with professional medical advice can help you lose a lot of fat.

Tesamoreline is a GHRH, so you will see an increase in plasma Growth Hormone levels. You can expect an increase in insulin-like growth factor (IGF-1) following injections, which has other benefits such as cell growth in skin and hair.

Tesamorelin Overview

⭐️ Top Benefits: Increases natural HGH production
🧪 Form: Injectable liquid
⌛️ Max Time Used: 14 weeks
💰 Average Cost: $91.99
❤️‍🩹 Side Effects: Insulin resistance
☢️ Dangers: Not really
📚 Best Peptide Stack: GHRP / HGH / IGF-1
Men/Women: Men and women
➡️ Go to the Full review

  • Muscle gain
  • Fat Loss
  • Increased bone density
  • Injection site pain
  • Insulin resistance
#3 Best GHRP


Hexarelin is a GHRP, something that is often combined with a GHRH. Hexarelin can be used to increase GH secretion and thereby, the user has better growth factors.

The human body responds quite well to increased levels of GH, with minimal side effects. You can expect to see fat loss benefits, lean muscle growth, and other benefits such as collagen production.

Hexarelin is not as common as CJC or Ipamorelin, but there are plenty of clinical trials showing that it is effective.

Hexarelin Overview

⭐️ Top Benefits: Increases natural HGH production
🧪 Form: Injectable liquid
⌛️ Max Time Used: Up to 3 months
💰 Average Cost: $42.99
❤️‍🩹 Side Effects: Insulin resistance
☢️ Dangers: Not really
📚 Best Peptide Stack: HGH / IGF-1 / GHRP / CJC-1295
Men/Women: Men and women
➡️ Go to the Full review

  • Muscle gain
  • Fat Loss
  • Increased bone density
  • Injection site pain
  • Insulin resistance
  • Higher cortisol levels
  • Increased prolactin levels
  • Insulin desensitization
  • Low libido
  • Fatigue and lethargy
#4 Best Fat Loss HGH Peptides

HGH-Fragment or AOD 9604

Both of these are Peptides that are “related” to Growth Hormone but can still cause a significant reduction in fat mass. They will not be doing much for muscle growth, however.

These can both be used to improve your body composition. Fragment or Frag is a part of the Growth Hormone Amino Acid chain, particularly the last 15 amino acids (176-191).

AOD 9604 on the other hand is a modified version of those same amino acids (176-191), granting AOD the ability to manage injuries by increasing red blood cells and decreasing inflammation.

Neither Frag nor AOD will increase insulin resistance.

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Read Full Biotech Peptides Review

  • Fat loss from HGH without the insulin resistance
  • Less chance of bloating
  • While there are studies on it, more are needed
#5 Non Peptide HGH Booster


MK 677 is commonly grouped with SARMs when in reality it is not a SARM at all. It is also not a Peptide. Regular SARMs will bind to the Androgen Receptors in the muscle tissue (and bone tissue as well) to cause an increase in muscle protein synthesis.

MK 677, however, is a Growth Hormone secretagogue, meaning it will not interact with the Androgen Receptors at all, but only cause an increased release of Human Growth Hormone (HGH) from your own Pituitary gland.

Increased HGH can lead to increased fat loss, and muscle gain, and even improve overall life quality.

MK 677 Overview

⭐️ Top Benefits: Muscle growth, strength gain, fat loss
🧪 Form: Liquid, Powder
⌛️ Cycle Length: 8 – 12 weeks
💰 Average Cost: $64.99
❤️‍🩹 Side Effects: Water retention and gyno
☢️ Dangers: Hypertension
📚 Best Stack: Cardarine / LGD 4033 / RAD 140
PCT Required: No
🧍‍♂️🧍‍♀️Men/Women: Men and Women
➡️ Go to the Full review

  • Better recovery
  • Improved fat loss
  • Massive muscle gains
  • Water retention
  • Gyno

What are HGH Peptides?

The human body has something called the Somatropic Axis, which is the system in which the body will produce Human Growth Hormone. This is regulated by GHRH and somatostatin (SRIF).

The HGH that is produced from this Axis is vital for human health, and a Growth Hormone deficiency can lead to a poor immune system, depression, awful muscle recovery, low bone density, and various other ailments [3].

Best HGH Peptides for Muscle Growth
Figure 1: HGH has effects on the entire body due to its ability to increase IGF-1 levels

HGH peptides are Amino Acids that are bound to one another with Peptide bonds – hence the name. Growth Hormones can be administered to help individuals stimulate GH release from the Anterior Pituitary Gland, often called Peptide Therapy.

Peptide therapy is known for causing weight loss (fat), increase in muscle cells, bone density, life quality, and resulting in overall healthy adults.

How Do HGH Peptides Work?

Because of the massvie range of different Peptides, we will be focusing on GH secretion. These Peptides include CJC, Ipamorelin, etc.

In their injectable form, these Peptides will stimulate the release of your Endogenous Growth Hormone. This will in turn cause the following:

  • Increased release of Lipase which will lead to weight loss from Adipocites (fat cells)
  • Increased release of Glucagon which will lead to distribution of Glycogen into muscle cells
  • Increased release of insulin like growth factor 1, which has been known to be great for skeletal muscle, skin and hair health, and various other parts of the body as well
Best HGH Peptides for Muscle Growth
Figure 2: While HGH peptides can increase muscle mass, it is vasstly better at reducing fat mass

While HGH Peptides can increase muscle mass, there are other methods (hormones) that are better for this.

Benefits of HGH Peptides

The application of the Peptides yo would choose depends on what your needs are. This is why it is best to either work with a performance coach or a Peptide Clinic. Overall, HGH Peptides can have the following benefits:

  • Muscle Growth via the IGF-1 action
  • Better distrubution of endogenous Amino Acids
  • Improved body composition resulting in better overall health
  • Tissue repair
  • Clinical trials have also shown that HGH Peptides are amazingly good at helping people lose body fat
  • Decrease in oxidative stress

Again, the benefits you personally gain from these Peptides depend on the pharmacokinetics.

Both yes and no. Buying pure Human Growth Hormone is illegal – unless you have a prescription. In order to get one, you would need to work with a doctor at a HRT Clinic – which is rather easy if you do it online.

Buying other Peptides such as Growth Hormone Releasing Hormone and other synthetic Peptides is legal under the term “research chemicals” and “not for human use. This is why retailers online need to adhere to this nomenclature.

Best HGH Peptides for Muscle Growth
Figure 3: Online Telemed services like that suplied by Evolve Telemed are the best, safest, and legal way to get Peptide Therapy

If you are looking for the safest (and easiest) way to get the best result from any synthetic peptide – use an HRT Clinic.

Conclusion: Should I take HGH Peptides?

Do you feel you need it? You need to look at the symptoms you are experiencing in your life and make an adult decision regarding whether or not you would need them.

To reiterate, these can accelerate muscle growth, but not to such a large extent. They can be used in conjunction with diet and training for weight gain, however, clinical trials show that other methods are better.

If you are an older individual, they can be used quite effectively for lean muscle mass. Lean body mass is the single most important factor when thinking about aging, and as an anti-aging Peptide, it would help build muscle mass (in elders).

For everyone else, the benefits would be the loss of body fat, improved life quality, and better health. These subcutaneous injections are really effective at improving almost everything in your life.

Improved recovery time, better body composition, lower body fat, better hair, basically everything gets better – just watch your glucometer…

Best Peptides for Muscle Growth

The best would still be pure HGH, due to its strong effects on nutritional distrobution and IGF-1. It would also allow you to recover faster, allowing you more muscle building oppertunities in the gym.

How good is Growth Hormone for muscle?

Maybe a 5/10? There are better performance enhancing drugs for this such as Testosterone and SARMs. That said, those have far more side effects. Lean muscle growth will occur from HGH, but only slightly. The older you are, however, the more pronounced it would be.

How good is Growth Hormone for fat loss?

10/10. It is probably one of the best fat burners on the market with the least amount of side effects. You can use it at low doses and almost have zero sides.

What are Growth Hormone Secretagogues?

These are compounds that will simply convince your own body to produce more natural HGH. Instead of replacing your HGH with exogenous HGH, you simply have more of your own. Less effective than exogenous HGH, but doesn’t cause the negative feedback loop.

Is Human Growth Hormone legal?

No, HGH is not legal unless you have a medical prescription and treatment advice. You can get these (if needed) from a GP or from an online HRT clinic – the latter being far easier and usually a lot cheaper as well.

Still Have Questions?

Drop us a comment down below and one of our expert coaches will respond to it. We’ll also be answering questions on our Instagram!

1) The Growth Hormone and Insulin-Like Growth Factor Axis: Its Manipulation for the Benefit of Growth Disorders in Renal Failure VINCENT ROELFSEMA, ROSS G. CLARK JASN Jun 2001, 12 (6) 1297-1306; DOI: 10.1681/ASN.V1261297

2) Veldhuis JD, Keenan DM, Bailey JN, Miles JM, Bowers CY. Preservation of GHRH and GH-releasing peptide-2 efficacy in young men with experimentally induced hypogonadism. Eur J Endocrinol. 2009 Aug;161(2):293-300. doi: 10.1530/EJE-09-0270. Epub 2009 May 20. PMID: 19458139; PMCID: PMC2772823.

3) 60 YEARS OF NEUROENDOCRINOLOGY: The hypothalamo-GH axis: the past 60 years in Journal of Endocrinology

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Daniel Louwrens BSc PT

Daniel Louwrens BSc PT | Writer

Daniel Louwrens is a well-rounded fitness professional with over 10 years of experience in bodybuilding and fitness. He holds a BSc in Chemistry from the University of Western Cape and is a certified International Personal Trainer and Nutritionist. He is also a skilled bodybuilder and head coach for Muscle and Brawn. With his knowledge and expertise, he provides personalized training, nutrition, and recovery guidance to help clients reach their fitness goals.

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Rhonda Behunin
11 months ago

I want to try Sermorelin, but I can’t find the correct dosage. I would like to try a stack and use Peptidesciences, but they do not give dosage information. I am a female 128 lbs. thank you

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