Best SARMs for Weight Loss and Cutting

Feeling like you could get more Tinder matches if you occupied less real estate? Yeah. SARMs have been shown to aid in muscle gain and fat loss - but which are best?
Medically reviewed by Dr. Mohammed Fouda
Dr. Fouda uses his extensive knowledge and expertise as an academic scholar to medically review articles for scientific accuracy and credibility, ensuring that the medical information presented is up-to-date and trustworthy. He is responsible for ensuring the quality of the medical information presented on our website.

Let’s face it. You’re overworked. You’re stressed. Your pants don’t fit so great and you feel the need to switch off the lights before having sex.

I’ve been there. But fear not, there may be a solution. Not for the depression, just the fat though.

SARMs (Selective Androgen Receptor Modulators) have been all the rave these days, with people proclaiming that they could change your life, make you ripped, and so much more.

Is this just some weird scam like that lady with the deep voice and the blood pills, or are these SARMs legit? Let’s discuss the best SARMS for weight loss and find out.

Key Takeaways

  • SARMs (Selective Androgen Receptor Modulators) can be effective for weight loss by binding to specific receptors and causing changes in the body, but not all SARMs are the same.
  • Some SARMs are better at burning fat, while others focus on muscle gain and fat loss. Weight loss is primarily achieved through a caloric deficit and exercise.
  • Cardarine (GW501516) is a popular SARM for weight loss, as it accelerates weight loss and preserves muscle during a diet. It is known to increase vascularity and improve cardiovascular capabilities.
  • Andarine S4 is another effective SARM for weight loss, as it lowers lipoprotein lipase, accelerates fat loss, and promotes muscle retention and recovery.
  • MK-677, while not a SARM, can help with weight loss by increasing human growth hormone (HGH) release, which leads to fat loss and muscle gain.

Warning: The content on and the information included in this article is intended for entertainment and informational purposes only. It is not intended nor implied to be a substitute for professional medical advice. Prior to buying anything, check that it is compliant where you live with your current government laws. We frequently mention research chemicals that are not made for human consumption. Therefore, before purchasing any product for personal use, consult with your doctor or healthcare provider first.

So which are the Best SARMS for Weight Loss?

Weight loss will be predominantly determined by a caloric deficit, and hopefully, you’re doing some training as well. If not, go do some weights.

Regardless, if you’re looking for that fat-burning supercharger in the shape of the best SARMS for weight loss, here are the best options:

SARM NameCardarine GW501516Andarine S4MK-677
Top Benefits 🌟Endurance and fat lossMuscle growth, strength gain, fat lossMuscle growth, strength gain, fat loss
Form πŸ₯ƒLiquid, PowderLiquid, PowderLiquid, Powder
Cycle Length ⏱6 – 8 weeks6 – 8 weeks8 – 12 weeks
Average Cost πŸ’²$59.99$59.99$64.99
Side Effects ❎Liver toxicity and stomach painVision issues, headaches, liver toxicityWater retention, gyno
Dangers ☠HepatotoxicityHepatotoxicityHypertension
Best Stack πŸ₯‡MK-677 / Testolone / LGD 4033MK-677 / Cardarine / RAD 140Cardarine / LGD 4033 / RAD 140
PCT Required πŸ™…β€β™‚οΈNoYesNo
Men/Women πŸ€΅πŸ‘©Men and WomenMenMen and Women

#1 Best SARM for Weight Loss: Cardarine GW501516

One hell of a name, and one hell of a tool! Cardarine is an exceptional tool and one of the best SARMS for weight loss. It’ll preserve muscle loss while you’re on your diet, but also massively accelerate weight loss.

As mentioned earlier, Cardarine is technically not a SARM but a PPAR Delta Agonist. It’ll bind to PPAR Delta receptors, and cause the body to just burn more energy.

Usually dosed as a liquid shown here by Sports Technology Labs, you do sometimes find pills or capsules.

Cardarine is also known to increase vascularity – combined with weight loss this could also massively help with cardiovascular capabilities

#1) Best SARMs for Weight Loss: Cardarine

1) Best SARMs for Weight Loss: Cardarine (GW-501516)

Cardarine, recognized as a Peroxisome proliferator-activated receptor (PPAR) agonist, exerts its influence on receptors distributed throughout the body, including those on muscles. Through its binding with PPAR, Cardarine initiates various effects, such as enhanced endurance, a reduction in glucose metabolism, and the promotion of fat loss.

One notable benefit of Cardarine is its ability to accelerate lipid metabolization, facilitating the conversion of stored body fat into energy. This makes it a favored supplement among bodybuilders during contest preparation, seamlessly integrating into cutting stacks to optimize results.

Beyond its performance-enhancing aspects, Cardarine has demonstrated a positive impact on lipid profiles. It effectively lowers harmful LDL cholesterol levels while simultaneously boosting healthy HDL cholesterol. This dual action positions Cardarine as a potential safeguard against heart attacks, cardiovascular diseases, strokes, and blocked arteries. 

Remarkably, this compound stands out for not only enhancing physical performance but also contributing to cardiovascular healthβ€”a rare combination in the realm of performance-enhancing drugs. Cardarine’s unique attributes make it a popular choice, offering a multifaceted approach to both fitness enthusiasts and those seeking cardiovascular well-being.

Cardarine (GW-501516) Overview

⭐️ Top Benefits: Endurance and fat loss
πŸ§ͺ Form: Liquid, Powder
βŒ›οΈ Cycle Length: 6 – 8 weeks
πŸ’° Average Cost: $59.99
β€οΈβ€πŸ©Ή Side Effects: Liver toxicity and stomach pain
☒️ Dangers: Hepatotoxicity
πŸ“š Best Stack: MK-677 / Testolone / LGD 4033
PCT Required: No
πŸ§β€β™‚οΈπŸ§β€β™€οΈMen/Women: Men and Women
πŸ”„ See Results
➑️ Go to the Full review

  • Better recovery
  • Improved fat loss
  • Stomach cramps
  • Liver toxicity

#2 Best SARM for Weight Loss: Andarine S4

Next on our list for the best SARM for weight loss is Andarine S4. No, I’m not referring to the souped-up Audi, I’m talking about how souped-up you’re gonna be after taking S4!

Fun fact, souped-up comes from old horse racing when horses used to be fed the special sauce in their soup.

Anyways, S4 is quite a strong SARM. In fact, it’s widely advised not to be the first SARM you sign the dotted line with.

S4 will amplify your weight loss endeavors by lowering lipoprotein lipase, which will accelerate fat loss. It will also make you more anabolic, and the chances of you losing muscle will be very slim.

Bonus, it massively accelerates recovery periods as well! Hop on over to Sports Technology Labs to get yourself a flavored Andarine S4 – something you don’t find every day.

#2) Best SARMS for Weight Loss: S4 Andarine

#2) Best SARMS for Weight Loss: S4 Andarine

S4 Andarine, also known by its developmental code names GTx-007 and S-4, stands out as an investigational selective androgen receptor modulator (SARM) developed by GTX, Inc.

Initially intended for addressing conditions like muscle wasting, osteoporosis, and benign prostatic hypertrophy (BPH), S4 Andarine offers a unique approach to anabolic activity without the drawbacks associated with traditional anabolic steroids.

Notably, S4 Andarine showcases an anabolic potency comparable to testosterone, yet distinguishes itself by not suppressing luteinizing hormone (LH) or follicle-stimulating hormone (FSH). This unique feature allows it to enhance muscle and bone mass without impacting the prostate, minimizing the negative side effects commonly associated with anabolic steroid use.

Primarily recognized for its effectiveness as a cutting agent, S4 Andarine facilitates fat loss by reducing lipoprotein lipase (LPL) levels and mitigating water retention. Importantly, it safeguards hard-earned muscle mass during cutting phases and may even contribute to the development of lean muscle mass. 

With its potential to deliver anabolic benefits while minimizing unwanted side effects, S4 Andarine has garnered popularity among fitness enthusiasts seeking a safer and more targeted approach to achieving their physique goals.

S4 Andarine Overview

⭐️ Top Benefits: Muscle growth, strength gain, fat loss
πŸ§ͺ Form: Liquid, Powder
βŒ›οΈ Cycle Length: 6 – 8 weeks
πŸ’° Average Cost: $59.99
β€οΈβ€πŸ©Ή Side Effects: Vision issues, headaches, and liver toxicity
☒️ Dangers: Hepatotoxicity
πŸ“š Best Stack: MK-677 / Cardarine / RAD 140
PCT Required: Yes
πŸ§β€β™‚οΈπŸ§β€β™€οΈMen/Women: Men
πŸ”„ See Results
➑️ Go to the Full review

  • Better recovery
  • Improved fat loss
  • Massive muscle gains
  • Headaches
  • Liver toxicity
  • Vision issues

#3 Best SARM for Weight Loss + Increased Growth Hormone: MK677

No, I’m not talking about secret experiments or futuristic tech – I’m here to introduce you to the potential growth hormone powerhouse that is MK-677!

MK-677, also known as Ibutamoren, is not your typical SARM. It’s technically a growth hormone secretagogue that can significantly boost your body’s production of growth hormone. 

And why is that so appealing? Well, growth hormone plays a crucial role in various physiological processes, including muscle growth, fat loss, and overall well-being.

One of the most remarkable benefits of MK-677 is its ability to increase your growth hormone levels without the need for injections or synthetic hormones. 

Instead, it stimulates your body to release more growth hormone naturally. This can lead to improved muscle mass, fat metabolism, and even better sleep quality.

So, if you’re looking for a way to enhance your body’s anabolic state and potentially improve your body composition, MK-677 might be the way to go. 

It’s an option worth considering, especially if you’re already familiar with SARMs and want to explore a different avenue to achieve your fitness goals.

#3) Best SARMS for Weight Loss: MK-677

#3) Best SARMS for Weight Loss: MK-677

MK-677, often mistakenly grouped with SARMs, defies categorization as it is neither a SARM nor a peptide. While traditional SARMs exert their effects by binding to Androgen Receptors in muscle and bone tissue to stimulate muscle protein synthesis, MK-677 takes a distinct approach.

Functioning as a Growth Hormone secretagogue, MK-677 doesn’t interact with Androgen Receptors but triggers an augmented release of Human Growth Hormone (HGH) directly from the Pituitary gland. This unique mechanism sets MK-677 apart from traditional SARMs.

The increased secretion of HGH induced by MK-677 brings about several benefits. Elevated HGH levels have been linked to enhanced fat loss, muscle gain, and an improvement in overall life quality. It’s essential to recognize MK-677 as a Growth Hormone secretagogue rather than a SARM, as this distinction is crucial in understanding its mode of action and the varied outcomes it can offer. 

As a compound with the potential to influence growth hormone levels, MK-677 is carving its niche in the realm of performance enhancement and overall well-being, providing a unique avenue for those seeking diverse physiological benefits without directly engaging Androgen Receptors.

MK 677 Overview

⭐️ Top Benefits: Muscle growth, strength gain, fat loss
πŸ§ͺ Form: Liquid, Powder
βŒ›οΈ Cycle Length: 8 – 12 weeks
πŸ’° Average Cost: $64.99
β€οΈβ€πŸ©Ή Side Effects: Water retention and gyno
☒️ Dangers: Hypertension
πŸ“š Best Stack: Cardarine / LGD 4033 / RAD 140
PCT Required: No
πŸ§β€β™‚οΈπŸ§β€β™€οΈMen/Women: Men and Women
➑️ Go to the Full review

  • Better recovery
  • Improved fat loss
  • Massive muscle gains
  • Water retention
  • Gyno

What are SARMs?

The human body has Androgen receptors throughout, spread from muscles, and bones, to even the prostate.

They play a crucial role, as the natural Androgenic hormones humans produce need to bind at specific places for our bodies to function normally.

Thus, a good and safe amount of Androgenic hormones is all fine and good.

Steroids are exogenous Androgenic hormones. These bind to all of the androgenic receptors in the human body and cause a biological change in them.

This is great for muscle hypertrophy, but not so great for other parts – such as your prostate or your liver.

See, those will also undergo the change due to the exogenous hormones, and that’s how you end up with prostate cancer.

Best SARMs for Weight Loss

Steroids are often prescribed to individuals suffering from certain muscular atrophy illnesses, such as AIDS patients. In fact, AIDS patients are often prescribed Anadrol.

Anadrol is an extremely powerful oral steroid, and incredibly liver toxic. SARMs, like the RAD140 shown above, were designed to perform similarly to steroids in muscular hypertrophy but to not have the adverse effects associated with steroids.

SARMs, as the name suggests, are selective in nature, and will only (mostly) bind to the Androgen receptors within the muscles and bones, therefore having fewer side effects than steroids.

How do SARMs for Weight Loss Work?

Let’s uncover how SARMs help with weight lossβ€”it’s like they’re conductors guiding the body’s musical receptors.

SARMs, or Selective Androgen Receptor Modulators, are like instructors that latch onto specific receptors, giving clear directions for changes in certain areas of the body.

In the weight loss orchestra, some SARMs play the lead, not mimicking Testosterone at the receptor. 

Take Cardarine, for instanceβ€”it’s a standout player, acting as a PPAR Delta Agonist. This unique compound leads a harmonious dance of metabolic changes, creating an ideal setting for effective weight loss.

But the SARMs story unfolds with different characters. Each SARM adds its own flavor to the weight loss mix. 

Going beyond simple mimicry, these compounds make varied moves, boosting fat-burning with a special touch

In this biochemical dance, there’s a common tune – the promotion of muscle growth. Most SARMs join in this dance, creating a balanced blend of shedding fat while building lean muscle mass.

In the grand performance of biochemical ballet, SARMs redefine weight loss as a captivating composition. Each compound plays a unique role, creating a masterpiece of transformation. 

So, exploring how SARMs work unveils a symphonic elegance, making the journey of weight loss more than just a processβ€”it becomes a beautifully orchestrated performance.

Other Benefits of SARMs

Other BenefitsDescription
1) Lean Muscle Mass πŸ’ͺSARMs cause a significant increase in lean muscle mass, originally designed to aid hospital patients with muscle wastage.
2) Endurance πŸ‹οΈβ€β™‚οΈSARMs, such as Ligandrol, can enhance cardiovascular capabilities, benefiting athletes like Crossfitters.
3) Increased Bone Density 🦴SARMs bind to androgenic receptors in bones, promoting increased bone density, crucial for strength training.

SARMs are so much more than just a fat-burning booster, there’s a reason plenty of athletes started using these things.

1) Increase in Lean Muscle Mass

SARMs are very well known for causing an increase in lean muscle mass. They were originally designed for that purpose, to help hospital patients who are suffering from muscle wastage.

Plenty of bodybuilders, cross-fitters, and other athletes use SARMs like S23 for their potent muscle-building qualities.

2) Endurance

It won’t come as a surprise that some Crossfit athletes have been found to use SARMs, as they could really help their performance.

One of those benefits is the fact that SARMs can boost your endurance. Yup, SARMs like Ligandrol have been shown to significantly improve cardiovascular capabilities.

3) Increased Bone Density

Ever looked at your local powerlifter and thought “Wow 5 minutes rest between squats, jeez”. Me too. But have you also thought as to how their bones can cope with those massive squats??

Well, it won’t come as a surprise that weight training has been shown to increase bone density. Thus, having strong bones is certainly going to help you.

Guess what? SARMs bind to the androgenic receptors in your bones and increase their density.

So, are SARMs legal? It’s a bit of a gray area. The key is in the labeling – they must be marketed as “Research Chemicals” for legal purchase. Stray away from this designation, and you’re venturing into illegal territory.

For athletes in sports regulated by the World Anti-Doping Agency (WADA), the use of SARMs poses a challenge. Unfortunately, luck isn’t on their side, as these compounds are firmly banned in such competitive arenas.

Now, let’s delve a bit deeper into the legal nuances. The legality of SARMs lies in their classification as “Research Chemicals,” a label that grants them a legal status, at least in the context of purchase and possession.

However, the intricacies don’t end there. Athletes, in particular, need to tread carefully. WADA, the authoritative body overseeing anti-doping measures, has cast a wide net, capturing not just performance-enhancing substances but also caffeine. 

Yes, that’s right – even something as innocent as consuming too much coffee before a test can lead to a ban.

This legal puzzle surrounding SARMs reflects the broader landscape of substances straddling the line between research and illicit use. 

It emphasizes the need for users to be well-versed in the regulatory intricacies surrounding these compounds. 

The blurred boundaries of legality underscore the importance of responsible and informed decision-making, especially for those engaged in competitive sports where adherence to anti-doping regulations is paramount.

The legality of SARMs hinges on careful adherence to their designated status as “Research Chemicals.” 

Straying beyond this label not only poses legal risks but also highlights the evolving challenges in navigating the complex terrain of substances that blur the line between research and potential misuse.


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Side Effects of SARMs

Regrettably, every rose has its thorn. Indulging in chips may bring guilt, exploring online dating may bring unexpected outcomes, and cruising in a Tesla may evoke a sense of smugness.

Similarly, the use of SARMs is not without its consequences, and these effects tend to be intricately tied to the dosage. In simple terms, the more you use, the more pronounced the side effects become.

The manifestation of side effects can vary widely, influenced by individual factors and the specific type of SARM in play.

Let’s take a closer look at some of the most prevalent and noteworthy side effects associated with these compounds.

1) Testosterone Suppression

Yup, even SARMs can do this. See, normally exogenous Testosterone will suppress your endogenous production of Testosterone.

SARMs, most of them at least, do not cause this at all. Some SARMs such as the aforementioned S4 can do this.

In this scenario, it might be best to make use of a PCT (post-cycle treatment) to keep your testes functioning.

2) Organ Damage

While SARMs were designed to not be as toxic as steroids, they unfortunately are still toxic, just like your ex. Specifically the liver and kidneys.

See, all oral steroids and SARMs need to be broken down by the liver, and that process does put a fair bit of strain on the liver. Solution? Lower doses, or just use the correct supplements.

3) Cholesterol

Another common side effect we hear steroid users complain about is, “Oh, my lipids are out of range.”. Basically, they have cholesterol issues.

This is something that SARMs definitely do cause, as quite a few studies (and anecdotal evidence) do show that SARMs lower HDL (the good cholesterol).

Who should use SARMs for Weight Loss?

Adults. If you haven’t completed puberty or you’re not fully developed, walk away. If you are an adult, and you are looking to get a slight edge in your weight loss journey, it could very well be for you.

Just make sure you study the specific side effects associated with the SARM you intend on using – for instance, don’t use SARMs unless your lipids are in range.

Best SARMS for Weight Loss

That being said, you’re still gonna have to work. SARMs won’t magically you look like Chris Hemsworth.

Dieting, training, rest, and supplementation, all still play the biggest roles when it comes to weight loss.

Common Questions on SARMs

How much weight can I lose on SARMs?

It depends. Someone with 30% body fat is going to lose a lot faster than someone at 3%. Optimally, you’d aim to lose between 0.5 – 1.0 % of body weight per week.

Do you lose your gains after SARMs?

If you fail to train and diet correctly, yes. Keep on training and dieting, you could end up keeping 80% of your gains.

Do I gain the fat back after SARMs?

Again, if you keep eating correctly and training, you’ll gain minimal fat.

Do SARMs increase Aggression?

Some do yes. The stronger SARMs like S23 could potentially increase aggression whilst on the cycle.

What is the safest SARM for cutting?

RAD 140, MK 677 and LGD 4033 are considered 3 of the safest SARMs for cutting.

Conclusion: The Best SARM for Weight Loss

In the realm of weight loss, exploring the landscape of Selective Androgen Receptor Modulators (SARMs) has uncovered a multitude of options, each with its unique profile and potential. 

From the potent fat-burning qualities of Cardarine to the muscle-building prowess of Ligandrol, the journey through the best SARMs for weight loss has been a nuanced exploration.

As we conclude this journey, it’s essential to recognize that while SARMs offer promising avenues for achieving fitness goals, responsible and informed use is paramount. 

Navigating the legal considerations, understanding potential side effects, and tailoring usage to individual needs are crucial aspects.

Remember, the pursuit of weight loss isn’t just a destination; it’s a holistic journey encompassing physical well-being and health. 

With the right knowledge and approach, incorporating the best SARM for weight loss into a comprehensive fitness strategy can unlock transformative possibilities

As the SARMs symphony continues to play, may your fitness endeavors be harmonious, balanced, and ultimately, rewarding.

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Daniel Louwrens BSc PT

Daniel Louwrens BSc PT | Writer

Daniel Louwrens is a well-rounded fitness professional with over 10 years of experience in bodybuilding and fitness. He holds a BSc in Chemistry from the University of Western Cape and is a certified International Personal Trainer and Nutritionist. He is also a skilled bodybuilder and head coach for Muscle and Brawn. With his knowledge and expertise, he provides personalized training, nutrition, and recovery guidance to help clients reach their fitness goals.

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Dr. Mohammed Fouda

Dr. Mohammed Fouda | Reviewer

Dr. Fouda uses his extensive knowledge and expertise as an academic scholar to medically review articles for scientific accuracy and credibility, ensuring that the medical information presented is up-to-date and trustworthy. He is responsible for ensuring the quality of the medical information presented on our website.

Read all articles
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