5 Best Peptides for Women (Injectable Energy + Weight Loss Peptides)

Peptides can help you lose weight, build muscle, and even improve your skin and hair health. But which peptides would be best for females?

Ladies, we all know you’re superheroes in your own right, but what if we told you there was a way to take your superpowers to the next level? Enter: peptide therapy!

Peptides are small chains of amino acids that can have powerful effects on the body, including promoting healthy aging, improving skin health, boosting immune function, and even aiding in weight loss in women.

In this article, we’ll not just explore the best peptides for weight loss in women, but also all the other ways peptides can benefit your health.

So, get ready to peptide your way to the top of your game – because who needs superpowers when you have peptides?!

Key Takeaways

  • Peptide therapy can offer benefits for women’s sexual health, anti-aging, lean muscle mass, skin health, and weight loss.
  • PT-141 is a popular peptide for female sexual health, while Palmitoyl Pentapeptide-4 (Matrixyl) is commonly used for anti-aging and Copper Peptides for skin health.
  • For those aiming to increase lean muscle mass or promote fat loss, GHRP-6 and Ipamorelin are two peptides to consider. However, it’s important to consult a healthcare professional before starting any peptide therapy.
πŸ§ͺ Peptide🎯 Main BenefitπŸ§ͺ FormβŒ›οΈ Cycle DurationπŸ’Έ Costβ€οΈβ€πŸ©Ή Side EffectsπŸ“š Stacks With⭐️ Additional Benefits
IGF-1Improved Muscle MassInjectable liquid2 – 3 Weeks$88.99Hypoglycemia and stomach discomfortHGHAnti-aging, Female fat burning, Improved life quality, Better hair and skin
IpamorelinFemale Fat LossNot specifiedUp to 3 months$52.99Insulin resistanceHGH / IGF-1 / GHRP / CJC-1295Increased bone density, Fat Loss
PT-141 (Bremelanotide)Female Sexual HealthNot specified6 – 12 Weeks$37.99Pain at the injection site and nauseaHGH / IGF-1 / Kisspeptin-10Increases sexual function
CJC 1295 + Ipamorelin StackIncrease in Lean Muscle Mass, Enhanced EnduranceInjectable8 to 12 weeks (60 to 90 days)Approximately $49Vertigo, Increased Body Temperature, Water Retention, Headaches, Injection Site Reactions, Increased Hunger, Lowered Blood Sugar LevelsNot specifiedImproved Fat Loss, Better Sleep Quality, Enhanced Recovery, Strengthening of Joints and Connective Tissue
Matrixyl PeptideSkin HealthTopical (cream)No cycling needed$191.99None reportedIpamorelin, GHK Peptides, and GlutathioneImproved skin health, Reduction in wrinkles

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#1 Semaglutide/IGF-1 Peptide for Female Lean Muscle Mass

Insulin-like growth factor 1 (IGF-1), also known as somatomedin C constitutes 70 Amino acids in its structure. This polypeptide hormone is structurally homologous to proinsulin and another factor called IGF-2. The polypeptide chains of IGF-1 are held together by disulfide bonds.

Produced primarily in the liver, its synthesis is upregulated by the growth hormone (GH). It is important to note that it is also produced locally in body tissues.

Most of the IGF-1 binds to the Insulin growth factor binding protein (IGF-BP). The subsequent binding significantly increases the half-life of IGF-1 in blood circulation.

IGF-1

IGF 1 refers to Insulin-Like Growth Factor, a natural hormone found in the body working in close relation to natural Growth Hormone production.

IGF 1 will virtually act on all of the body’s cells, looking at what it can do in muscle cells, it will boost protein synthesis, it might act as a glucose uptake aid, and it will also lead to a positive Nitrogen balance.

All of these form part of the perfect muscle-building environment, and thus IGF 1 LR3 can help with this when combined with training, diet, and the correct polypharmacology.

Another thing to consider is the fact that it could play a role in the downregulation of Glucocorticoids. This will not only massively reduce inflammation but thereby also boost recovery tremendously.

IGF-1 Overview

⭐️ Top Benefits: Anti-aging, improved muscle mass, fat loss, and improved life quality
πŸ§ͺ Form: Injectable liquid
βŒ›οΈ Max Time Used: 2 – 3 Weeks
πŸ’° Average Cost: $88.99
β€οΈβ€πŸ©Ή Side Effects: Hypoglycemia and stomach discomfort
☒️ Dangers: Hypoglycemia can be dangerous if unexpected
πŸ“š Best Peptide Stack: HGH
⚀ Men/Women: Men and women
➑️ Go to the Full review

  • Anti-aging
  • Muscle gain
  • Fat loss
  • Improved life quality
  • Better hair and skin
  • Hypoglycemia
  • Stomach discomfort

Ipamorelin: One of the Best Peptides for Weight Loss in Women

Ipamorelin is a growth hormone secretagogue that stimulates the release of human growth hormone, making it one of the best peptides for weight loss in women and for female fat burning.

It works by specifically targeting the anterior pituitary gland to promote the natural release of growth hormone, which can lead to increased fat metabolism and fat breakdown.

Additionally, Ipamorelin has been shown to inhibit lipogenesis (the formation of new fat cells), improve energy metabolism and insulin resistance, contributing to better glycemic control [1].

Available in various doses and versions, Ipamorelin is generally considered a cost-effective option for those seeking peptide therapy for weight loss.

Ipamorelin Summary

Ipamorelin

Ipamorelin stands out as a potent pentapeptide (Aib-His-D-2-Nal-D-Phe-Lys-NH2) with remarkable growth hormone (GH)-releasing properties, both in vitro and in vivo. This selective growth hormone-releasing peptide has garnered attention as a promising solution for female fat loss.

Scientific investigations reveal that Ipamorelin has the potential to elevate the body’s natural growth hormone production by an impressive 30%. Given the pivotal role of growth hormone in fat metabolism, this elevation becomes crucial for achieving effective fat loss.

As women, especially those aged 40 and above, experience a decline in natural growth hormone levels, their metabolism tends to slow down, leading to increased fat storage. Ipamorelin’s capacity to boost these levels can counteract this decline, potentially accelerating fat loss by up to 20%.

What sets Ipamorelin apart is its unique characteristic of not stimulating appetite, distinguishing it from other growth hormone stimulants. This feature allows women to harness its fat-burning properties without the counterproductive urge to consume more calories.

Furthermore, a compelling study demonstrated that individuals incorporating Ipamorelin into their regimen experienced a notable 14% reduction in visceral fat over a 12-week period. Visceral fat, often deemed “dangerous fat,” is associated with various health risks, underscoring the importance of its reduction for overall well-being.

In summary, Ipamorelin presents a scientifically backed approach to female fat loss by elevating growth hormone levels, hastening metabolism, and reducing detrimental visceral fatβ€”all achieved without triggering an increased appetite. This makes Ipamorelin a promising avenue for those seeking an effective and well-rounded solution to enhance their overall body composition.

Ipamorelin Overview

⭐️ Top Benefits: Increases natural HGH production
πŸ§ͺ Form: Injectable liquid
βŒ›οΈ Max Time Used: Up to 3 months
πŸ’° Average Cost: $52.99
β€οΈβ€πŸ©Ή Side Effects: Insulin resistance
☒️ Dangers: Not really
πŸ“š Best Peptide Stack: HGH / IGF-1 / GHRP / CJC-1295
⚀ Men/Women: Men and women
➑️ Go to the Full review

  • Muscle gain
  • Fat Loss
  • Increased bone density
  • Injection site pain
  • Insulin resistance

PT-141 Peptide for Female Sexual Health

PT-141 is a peptide that can help to increase sexual desire and arousal in women by activating melanocortin receptors in the brain, leading to prolonged stimulation and improved overall health [2].

Additionally, PT-141 has been also shown to be effective in treating erectile dysfunction in men.

This peptide works by increasing energy production and blood flow to the genital area, resulting in improved sexual function.

While PT-141 can be expensive, many users report positive results, reportedly taking the medication at least 30 minutes prior to sexual activity.

PT-141 (Bremelanotide)

PT-141, also referred to as Bremelanotide, is a synthetic analog of the alpha-melanocyte stimulating hormone. Due to structural resemblance, it acts as a potent agonist of melanocortin receptors located in different areas of the central and peripheral nervous system. 

Being a synthetic derivative of Melanotan II, it was initially developed for skin pigmentation by stimulating melanocytes to induce melanogenesis. However, it soon gained enough traction as a potential therapeutic drug to treat ED in men and sexual hypoactivity in women by elevating pleasure levels. 

Since its development, a handful of clinical trials have been performed, and because of its effective results, it has also been called β€œfemale viagra.” 

The sex peptide help improve the sex drive and revive the old memories associated with it. 

PT-141 Overview

⭐️ Top Benefits: Increases sexual function and libido
πŸ§ͺ Form: Injectable liquid
βŒ›οΈ Max Time Used: 6 – 12 Weeks
πŸ’° Average Cost: $37.99
β€οΈβ€πŸ©Ή Side Effects: Pain at the injection site and nausea
☒️ Dangers: Not really
πŸ“š Best Peptide Stack: HGH / IGF-1 / Kisspeptin-10
⚀ Men/Women: Men
➑️ Go to the Full review

  • Increases sexual function
  • Fat loss
  • Pain at the injection site
  • Nausea

CJC 1295 for Female Anti Aging

Matrixyl, also known as Palmitoyl Pentapeptide-4, is a popular peptide used in peptide injections for its anti-aging benefits.

It works by stimulating the production of collagen in the skin, which can help to reduce the appearance of fine lines and wrinkles. Matrixyl is a receptor agonist, meaning it binds to specific receptors in the skin and triggers a response [3].

It is considered a cost-effective option compared to other anti-aging treatments and comes in different versions with varying concentrations.

Matrixyl has received positive reviews for its effectiveness in reducing the signs of aging skin.

As a drug affinity complex, it mimics the action of natural peptides in the body, making it a popular choice among those seeking a more natural approach to skincare.

CJC 1295 + Ipamorelin Stack

This is the quintessential combination for Growth Hormone secretion. CJC-1295 is a Growth Hormone Releasing Hormone while Ipamorelin is one of the Growth Hormone Releasing Peptides.

Some studies are showing that using a GHRH and GHRP together will yield better results [2].

As this will massively increase your endogenous Growth Hormone release, you can expect similar results to taking pure HGH. Benefits include weight loss, muscle growth, and better body composition, and various human studies found that people just feel better on HGH therapy.

This is a very common peptide stack and is going to result in a better life, and potentially, your desired physique.

Stack Overview

⭐️ Top Benefits: Increase in Lean Muscle Mass, Enhanced Endurance, Improved Fat Loss, Better Sleep Quality, Enhanced Recovery, Strengthening of Joints and Connective Tissue.
πŸ§ͺ Form: Injectable.
πŸ’‰ Typical Dosage: CJC-1295: 1000 mcg to 2000 mcg per week; Ipamorelin: 200 mcg to 300 mcg per day.
βŒ›οΈ Typical Cycle Duration: 8 to 12 weeks (60 to 90 days).
πŸ’° Average Cost: Approximately $49 (Prices may vary depending on the supplier and product concentration).
βœ… Availability: Easily available through various online peptide suppliers, but a prescription may be required in some regions.
β€οΈβ€πŸ©Ή Side Effects and Dangers: Vertigo, Increased Body Temperature, Water Retention, Headaches, Injection Site Reactions, Increased Hunger, Lowered Blood Sugar Levels.
πŸ”„ See before and after
➑️ Go to the Full review

Matrixyl Peptides for Female Skin Health

Matrixyl, also known as Palmitoyl Pentapeptide-4, is a popular peptide used in peptide injections for its anti-aging benefits.

It works by stimulating the production of collagen in the skin, which can help to reduce the appearance of fine lines and wrinkles. Matrixyl is a receptor agonist, meaning it binds to specific receptors in the skin and triggers a response [3].

It is considered a cost-effective option compared to other anti-aging treatments and comes in different versions with varying concentrations.

Matrixyl has received positive reviews for its effectiveness in reducing the signs of aging skin.

As a drug affinity complex, it mimics the action of natural peptides in the body, making it a popular choice among those seeking a more natural approach to skincare.

Matrixyl Peptide Summary

Matrixyl Peptide

Anti-aging is one of the hot topics in the world we live in today. This includes things like improving your hair health, skin quality, bone density, and muscle mass.

While some peptides are focused on helping you build mass, Matrixyl Peptide(s) are focused on solely improving your skin health and complex.

Matrixyl interacts with specific receptors which activate certain genes involved in the process of extracellular matrix renewal and cell proliferation. This whole process shows on the skin as a reduction in wrinkles and fine lines on the skin.

It is considered a cost-effective option compared to other anti-aging treatments and comes in different versions with varying concentrations. Matrixyl has received positive reviews for its effectiveness in reducing the signs of aging skin.

You’ll find Matrixyl in various OTC skin remedies since its introduction in 2000.

Features

πŸ’‰ Forms : Topical (cream)
πŸ•‘ Cycle Length:
No cycling needed
πŸ’Š Dosage: Used as a cream, no dosing specified
Benefits: Improved skin health and a reduction in wrinkles
πŸ’Έ Cost : $191.99
⚠️ Side Effects: None reported
Stacks: Ipamorelin, GHK Peptides, and Glutathione

  • Improved skin
  • Reduction in wrinkles
  • None

What Peptide makes you look younger? 

One of the other synthetic peptides that is known for its anti-aging effects on women’s skin is Acetyl Hexapeptide-8, also known as Argireline.

Argireline works by reducing the appearance of fine lines and wrinkles by inhibiting the movement of facial muscles, similar to how Botox works. It is often used as an alternative to Botox, as it is non-invasive and has fewer potential side effects [6].

In addition to its anti-aging properties, Argireline also has antioxidant properties, which can help to protect the skin from damage caused by free radicals [6].

Argireline can be found in various anti-aging skincare products and is generally considered safe for use. However, it’s important to note that results may vary depending on the individual and the product’s formulation.

What Peptide is best for tightening skin?

Argireline has also been found to have other therapeutic benefits for the skin, particularly in terms of tightening and firming.

As it works by relaxing facial muscles, it leads to a reduction in the appearance of wrinkles and fine lines. Additionally, Argireline has been shown to stimulate the production of collagen and elastin, two proteins that are essential for maintaining the elasticity and firmness of the skin [6].

With consistent use, Argireline can help to tighten and tone the skin, giving it a more youthful and vibrant appearance. Its effectiveness and safety have made it a popular ingredient in many skincare products designed to combat the signs of aging.

How Do Peptides Work?

Peptide therapy involves the use of peptides, which act as building blocks in the human body. Peptides work by binding to specific receptors in the body, triggering a wide range of biological responses.

There are many different types of peptides, each with its own unique properties and functions. Some peptides work by stimulating the production of other peptides or proteins, while others have anti-inflammatory or immune-boosting effects.

Argireline is a specific peptide that works by inhibiting muscle contractions in the face, which can reduce the appearance of fine lines and wrinkles. This is because repetitive facial movements can cause dynamic wrinkles over time, and Argireline helps to relax the muscles responsible for these movements.

In addition to its anti-aging effects, Argireline also has antioxidant properties that help to protect the skin from free radical damage. With consistent use, Argireline can help to improve the overall appearance and health of the skin, giving it a more youthful and radiant look.

Benefits of Argireline

Reduces the appearance of wrinkles

Argireline has been shown to be effective in reducing the appearance of wrinkles and fine lines, particularly those caused by repetitive facial movements.

Safe and non-invasive

Unlike invasive anti-aging treatments like Botox, argireline is a safe and non-invasive alternative that can be applied topically.

Antioxidant properties

Argireline has antioxidant properties that help to protect the skin from damage caused by free radicals, which can contribute to premature aging.

Stimulates collagen production

Argireline stimulates the production of collagen, a protein that is essential for maintaining the elasticity and firmness of the skin.

Improves overall skin health

With consistent use, argireline can help to improve the overall health and appearance of the skin, resulting in a more youthful and radiant complexion.

πŸ’‰Become a Peptide Expert (Protect your Health) πŸ’‰

Take our FREE 25-email course to learn everything you need to know about the scientific application of peptides. Discover how to protect your health, avoid sketchy peptide vendors, and stop wasting your hard-earned money. πŸ”₯ πŸ§ͺ πŸ’Š πŸ’ͺ πŸ’‰ 🩸πŸ₯ πŸ₯Ž

Side Effects of Argireline 

Dryness

Some people may experience dryness or flakiness of the skin with Argireline use. This is because the peptide can affect the moisture levels in the skin, leading to dehydration. It is important to use a moisturizer alongside Argireline-containing products to help counteract this effect.

Sensitivity

Argireline can cause skin sensitivity in some people, particularly those with sensitive skin. This can lead to redness, itching, or a burning sensation. It is important to patch test new skincare products containing Argireline before use to ensure that you are not allergic or sensitive to the ingredient.

Muscle weakness

Argireline works by inhibiting muscle contractions, which can lead to muscle weakness in the face with prolonged use. While this effect is temporary and typically resolves once use of the product is discontinued, it is important to use Argireline-containing products in moderation to avoid overuse and potential muscle weakness. 

Results of Argireline

“I have been using this for about a week now and I agree that it’s magic. I have very pronounced 11 lines, which I have had botoxed previously but I wasn’t motivated to continue doing that, so was happy to hear about Argireline. I noticed almost instant results, didn’t completely eliminate the 11’s but the much smaller lines and creases disappeared, which was nice. They do come back but perhaps with continued used they will disappear forever! As for the reason I bought it, my grand canyons, there’s been a noticeable improvement. Not huge, but certainly progress. Experience wise, the price is low (into my “sure why not” category). The watery consistency is fine, it doesn’t run all over your face. I did find it takes a little time to dry in. I have had no adverse reaction or breakout and I have been using it mostly twice a day. I have used it with niacinamide (Paula’s choice 10% booster at the moment, but will be going back to TO) and retinol (Medik8 6TR) and no issues with those.”

– Reddit User alkennedy1

Conclusion: Best Peptides For Female Fat Burning, Weight Loss, Anti-Aging, and more

In conclusion, the world of peptides offers many exciting possibilities for women looking to enhance their overall health and beauty. From anti-aging to sexual health, there’s a peptide for every need, and above we’ve listed some of the best peptides for weight loss in women as well as other health benefits.

So go ahead, give your body the TLC it deserves and unleash your inner Wonder Woman with the power of peptides!

People Also Ask

Should women take peptides?

While it is completely safe, whether or not women should take peptides depends on their individual health goals and needs. With proper guidance and monitoring, peptides can be a safe and effective addition to a woman’s health and beauty routine.

Do peptides burn belly fat?

Peptides may have the potential to help with burning belly fat, as some peptides have been shown to promote fat loss and improve metabolic function. While peptides are no magic potion, with balanced diet and regular exercise, you’re sure to see some astonishing results.

What are the side effects of peptides for women?

Peptide-containing topical creams and ointments have been associated with skin symptoms such as sensitivity, rash, and itching. Peptide injections may also cause swelling on site. It is highly recommended to discontinue use if any adverse reactions occur.

How fast do you see results from peptides?

The noticeable effects of peptide therapy may take up to 12 weeks, with another three months before improvements become apparent. However, some individuals report feeling increased energy, better sleep, and other subtle changes within just a few weeks of beginning peptide therapy.




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Gao Y, Yuan X, Zhu Z, Wang D, Liu Q, Gu W. Research and prospect of peptides for use in obesity treatment (Review). Exp Ther Med. 2020 Dec;20(6):234. doi: 10.3892/etm.2020.9364. Epub 2020 Oct 16. PMID: 33149788; PMCID: PMC7604735. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7604735/

Molinoff PB, Shadiack AM, Earle D, Diamond LE, Quon CY. PT-141: a melanocortin agonist for the treatment of sexual dysfunction. Ann N Y Acad Sci. 2003 Jun;994:96-102. doi: 10.1111/j.1749-6632.2003.tb03167.x. PMID: 12851303. https://pubmed.ncbi.nlm.nih.gov/12851303/

Aldag C, Nogueira Teixeira D, Leventhal PS. Skin rejuvenation using cosmetic products containing growth factors, cytokines, and matrikines: a review of the literature. Clin Cosmet Investig Dermatol. 2016 Nov 9;9:411-419. doi: 10.2147/CCID.S116158. PMID: 27877059; PMCID: PMC5108505. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5108505/

Bresciani E, Rizzi L, Coco S, Molteni L, Meanti R, Locatelli V, Torsello A. Growth Hormone Secretagogues and the Regulation of Calcium Signaling in Muscle. Int J Mol Sci. 2019 Sep 5;20(18):4361. doi: 10.3390/ijms20184361. PMID: 31491959; PMCID: PMC6769538. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769538/

Borkow G. Using Copper to Improve the Well-Being of the Skin. Curr Chem Biol. 2014 Aug;8(2):89-102. doi: 10.2174/2212796809666150227223857. PMID: 26361585; PMCID: PMC4556990. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4556990/

Lim SH, Sun Y, Thiruvallur Madanagopal T, Rosa V, Kang L. Enhanced Skin Permeation of Anti-wrinkle Peptides via Molecular Modification. Sci Rep. 2018 Jan 25;8(1):1596. doi: 10.1038/s41598-017-18454-z. Erratum in: Sci Rep. 2018 Apr 20;8(1):6500. PMID: 29371611; PMCID: PMC5785486. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5785486/

Contributors

Priyal Gandhi B.Sc

Priyal Gandhi B.Sc | Writer

Priyal is a seasoned Pharmaceutical Consultant and Technical Writer with a B.Sc degree and CAPM certification. With over 7 years of experience, Priyal has helped numerous clients with drug importation and launch of 15+ new drugs and nutraceuticals. She reviews scientific records including formulation, research and development, product testing, stability, and worldwide shipments to ensure regulatory compliance and successful market entry.

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Terressa Clark
Terressa Clark
9 months ago

I took Hcg and I loved it! is there anything like it? Semaglutide seems so confusing.

Daniel Louwrens BSc PT
Admin
7 months ago
Reply to  Terressa Clark

No, Semaglutide is WILDLY different, comparing apples to sausages

Haley C Hansen
Haley C Hansen
6 months ago

Ive been on AOD for about 3 months, little to no results. I eat so clean, 95% organic, in the gym 4-5 days a week, labs are great. Should I keep going? I’m just trying to lose some stubborn body fat. Is there a better peptide that helps shed body fat and gain muscle?

Daniel Louwrens BSc PT
Admin
4 months ago
Reply to  Haley C Hansen

AOD will not help with gaining muscle. Eating organic will not help you gain muscle or lose fat. Eating clean will not help you gain muscle or lose fat. Eating less than you need causes fat loss, eating more than you need (combined with resistance training) causes muscle gain.

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