LGD 3033 Review

In contrast to the more popular LGD 4033, LGD 3033 does appear to be better for fat loss - could this be the new cornerstone of your summer cut stack?

“You can’t gain and shred at the same time bro!” – something we know to be 100% true thermodynamically; unless you’re someone like Phil Heath or perhaps, if you make use of this wee little SARM called LGD 3033. With promises of increasing lipolysis and muscle gain at the same time, it has big shoes to fill…

Like all SARMs (Selective Androgen Receptor Modulators) LGD 3033 is selective in its nature, no surprise there. Thus, it’ll have less side effects than a typical steroid such as Trenbolone – but is that really true? Can SARMs really be that great with such little drawbacks?

Because SARMs occupy such a grey area in science currently, we really need to take a good look at how LGD 3033 works, and how you can use it to get the best results.

What is LGD 3033?

LGD 3033 is what’s known as a SARM, or a Selective Androgen Receptor Modulator. SARMs are mostly experimental compounds designed to work in a manner comparable to steroids, but without the common androgenic side effects associated with steroids.

LGD 3033 Review

As the name suggests, SARMs like LGD 3033 are selective in their nature. This trait means they are much more specific in their actions on the human body compared to steroids which kind of have a kitchen sink approach, the latter just blasting all receptors in sight.

LGD 3033 is the newer version of LGD 4033 from Ligand Pharmaceuticals. Being a different version, there are of course difference amongst the two. Originally, both were designed as a treatment for osteoporosis (1).

Disclaimer: The information included in this article is intended for entertainment and informational purposes only. It is not intended nor implied to be a substitute for professional medical advice. Prior to buying anything, check that it is compliant where you live with your current government laws.

How does LGD 3033 work?

Like all SARMs, LGD 3033 bind to certain receptors to act upon them. SARMs bind to androgen receptors to stimulate change in your DNA resulting in muscle growth, fat loss, and more. This is very similar to the way that Testosterone work, however using exogenous testosterone has (dose dependant) larger side effects.

SARM Mechanism

In stark contrast to using exogenous testosterone, using SARMs doesn’t have these stereotypical side effects. Side effects associated with testosterone include testicular shutdown, prostate growth, hair loss, and if not managed even estrogenic sides (2).

While LGD 3033 is a SARM and shouldn’t have suppressive effects on natural testosterone, it is actually very common knowledge that making use of a PCT or at least a PCT Supplement to help combat the suppressive effects that LGD 3033 has.

Benefits of LGD 3033

When compared to LGD 4033, LGD seems to have more fat burning effects. However, don’t limit LGD 3033 to only being a better fat burner…

1) Muscular Hypertrophy

Due to the nature in which LGD 3033 works upon the androgen receptors, it will result in enhanced nitrogen retention. This will cause increased muscle protein synthesis, which is just fancy for “You gonna gain bruh!”. You’ll also look a tad fuller, which is great if you’re using LGD 3033 for its aesthetics properties.

2) Fat Loss

As mentioned before, you will see accelerated fat loss. LGD 3033 increases the metabolic activity of the body, therefore you’ll just burn more energy just going about your day. Bonus, the increase in muscle mass will lead to further fat loss (not massive but every bit counts) due to the “bro science” that bigger dudes just burn more calories – this isn’t actually bro science it’s just a fact.

3) Increased Bone Density

This is for the strong boys & gals. LGD 3033 has been shown to in a recent study (3) to increase bone density in rats. Increased bone density will allow you (or your bones at least) to handle heavier loads whilst competing in strength sports.

4) Enhanced Recovery

With all androgenic compounds you will see an increase in recovery, as more blood flow can force more nutrients towards the muscles resulting in more recovery.

Side Effects of LGD 3033

Most SARMs have minimal side effects, however LGD does have a few side effects that are worth mentioning.

1) Possible Testosterone Suppression

SARMs don’t usually suppress testosterone or LH (Luteinizing hormone) in the male body, however some SARMs like YK-11, S23 and possibly LGD 3033 tend to do this. Due to their suppressive nature, you will have to make use of a SERM to stimulate the LH in your body – Enclomiphene, Nolvadex or Clomid will do.

2) Increased Libido and Aggression

Due to the androgenic nature of the compound, an increase in sex drive and aggression are going to be noticed. Not necessarily bad effects, but the aggression is something that needs to be managed if you are very prone to be aggressive anyways.

3) Cholesterol

Again, due to the nature in which LGD 3033 works, the androgenic effects it has on the body can result in an increase in bad cholesterol (LDL) and decrease in the good cholesterol (HDL). This might be something that you don’t want to pay attention to, but beware. Blood Lipids are nothing to play with,

Who should use LGD 3033?

Anyone looking to have a good boost in training, in regards to fat loss and muscle gain will definitely benefit from LGD 3033. Do keep in mind that this is no miracle pill, that you’ll still have to put in the work, diet, and train. Imagine this SARM (and every SARM in general) to be the icing on the cake.

I would not recommend this for anyone suffering from high blood pressure or high cholesterol. Also, I cannot imagine that this will be great for your cardiovascular system. Lastly, if you’re uncomfortable running the risk of having endogenous testosterone suppressed, then maybe look for a milder SARM for fat loss.

How to use LGD 3033

Hopefully, the first step you take is to make sure you’re healthy and if you’re even capable of using LGD 3033. After you’ve made that decision that you are indeed in good enough health to use it, there are a few things to keep in mind. The half life of this oral compound is about 6 hours, thus it is best taken multiple times a day – splitting the dose up equally (Usually three times).

1) Beginner Cycles

Purpose of Usage πŸ“ŒDosage βš–Length of Time ⌚
Cutting10mg per day, divided into three doses6 – 8 Weeks
Bulking10mg – 20mg per day, divided into three doses6 – 8 Weeks

Keep in mind a higher dose will result in more side effects.

2) More Experienced Cycles

Purpose of Usage πŸ“ŒDosage βš–Length of Time ⌚
Cutting20mg per day, divided into three doses6 – 8 Weeks
Bulking20mg per day, divided into three doses6 – 8 Weeks

This does not include the PCT part which I highly recommend since LGD 3033 is suppressive.

LGD 3033 PCT

Due to the suppressive nature of LGD 3033, a PCT is highly advisable. Going even further, managing estrogenic side effects whilst on your cycle might be a good idea, but obviously person dependent. Personally, I don’t think there is need for Aromasin or another AI (Aromatase Inhibitor) – however an over the counter AI supplement like Estrogenix from Hi Tech Pharmaceuticals might be a good idea.

AI Supplement

Regarding PCT, the type and intensity of product you use will be determined by how aggressive your LGD 3033 cycle was. For very mild cycles, you could get away with just using an over the counter PCT supplement like ArimiPlex from Hi Tech Pharmaceuticals which will do you just fine.

PCT Supplement
Best PCT
LGD 3033 Review

Tamoxifen by Swiss Chems

For much more intense cycles, you’ll do better off with Nolvadex or Clomid. Personally, I prefer Nolvadex purely because Clomid makes you feel like absolute sh*t. Swiss Chems can hook you up with some Nolvadex (Tamoxifen).

Is LGD 3033 legal?

SARMs can currently be sold as “Research Products only. Thus, it needs to be sold as “experimental”, as it hasn’t been approved by the FDA. SARMs are also on the WADA (World Anti-Doping Agency) banned list.

Where can I buy LGD 3033?

Finding LGD 3033 retailers online is actually quite hard at the moment, but there are some alternatives you can look too to get similar results.

1) Andarine S4

S4

Andarine S4 from can yield similar fat loss results, while also giving you that dry look that is associated with LGD 3033. Swiss Chems does stock oral S4.

2) Ostarine MK 2866

Ostarine Liquid

Ostarine MK 2866 is widely known as the beginner SARM due to the fact that it is much milder in its execution. Regardless, Ostarine will still be great for a fat loss phase whilst retaining a significant amount of muscle. Behemoth Labz stock both tablets and liquid Ostarine.

LGD 3033 vs Other SARMs

1) LGD 3033 vs LGD 4033

The first one that springs to mind obviously. Despite the fact that they were developed by the same company, they have slightly different applications. LGD 3033 is going to have a greater effect on fat loss compared to LGD 4033. Also, it’s a whole lot easier getting your hands on the latter.

2) LGD 3033 vs Cardarine

Cardarine  is one of the most popular SARMs for fat loss. Compared to LGD 3033, fat loss results can be similar (although I personally think you’ll get more from LGD 3033). LGD 3033 does has the added effect of being better for muscle retention, however Cardarine might be better for cholesterol levels…

FAQ’s about LGD 3033

1) Does LGD 3033 mess with Testosterone

Yes. LGD 3033 can be very suppressive in its nature, thus a PCT is highly recommended. Even managing estrogen whilst on cycle is also something to consider, as messing with testosterone results in alterations in estrogen levels as well.

2) Is LGD 3033 good for bulking?

Good? Yes. The best? No. You use the best tools for the job at hand, and LGD 3033 is definitely more of a fat burning compound. Muscle building, SARMs include things like YK-11, and LGD 4033 are going to be a better tools for bulking.

3) How safe is Ligandrol?

This one is actually really hard to answer. Medically, no they aren’t because otherwise the FDA would approve them. Anecdotally, they appear to be – with various of users having positive results when using conservative doses with a good PCT in place as well.

4) Which SARM is the Strongest?

The strongest SARM is a toss up between RAD 140 and S23.

Conclusion

LGD 3033 is a great little compound, although it is extremely hard to find at the moment, for the purpose of cutting weight it can do you wonders – granted you pay the compound the respect it deserves and use it wisely.

Best Steroid Stacks for Sale

We've scoured the web for our favorite steroid stack alternatives and came up with this.

Crazy Bulk has the bulking stack with alternatives to Dianabol, Trenbolone, Deca Durabolin and Testosterone.

They also have the cutting stack with alternatives to Anavar, Winstrol, Clenbuterol and Testosterone.

If you're interested in more potent compounds you can always check out the latest research on SARMs.

1) Vajda EG, LΓ³pez FJ, Rix P, Hill R, Chen Y, Lee KJ, O'Brien Z, Chang WY, Meglasson MD, Lee YH. Pharmacokinetics and pharmacodynamics of LGD-3303 [9-chloro-2-ethyl-1-methyl-3-(2,2,2-trifluoroethyl)-3H-pyrrolo-[3,2-f]quinolin-7(6H)-one], an orally available nonsteroidal-selective androgen receptor modulator. J Pharmacol Exp Ther. 2009 Feb;328(2):663-70. doi: 10.1124/jpet.108.146811. Epub 2008 Nov 18. PMID: 19017848.

2) Solomon ZJ, Mirabal JR, Mazur DJ, Kohn TP, Lipshultz LI, Pastuszak AW. Selective Androgen Receptor Modulators: Current Knowledge and Clinical Applications. Sex Med Rev. 2019;7(1):84-94. doi:10.1016/j.sxmr.2018.09.006

3) https://investor.ligand.com/press-releases/detail/81/ligand-announces-positive-preclinical-data-on-selective

Daniel Louwrens

Hi there! My name is Daniel Louwrens, and I have more than 10 years of experience in the bodybuilding & fitness world. I have graduated with a degree in Chemistry, and my aim with helping people is to educate people who have questions about anything and everything fitness: Training, Nutrition, Recovery, and PED's.

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