Cardarine (GW-501516)? – Cycle, Dosage, And Side Effects!

GW-501516, better known as Cardarine, has become one of the most popular cutting agents used by bodybuilders and athletes to get lean as quickly as possible.
Cardarine (GW-501516)

GW-501516, better known as Cardarine, has become one of the most popular cutting agents used by bodybuilders, athletes, and people who want to get lean as quickly as possible. It has become one of the most sought-after SARMs on the market, even though it is not technically a SARM at all.

In this article, I’ll give you the straight truth on everything you need to know in order to make a decision about taking GW-501516.

Warning: The content on Muscleandbrawn.com and the information included in this article is intended for entertainment and informational purposes only. It is not intended nor implied to be a substitute for professional medical advice. Prior to buying anything, check that it is compliant where you live with your current government laws. We frequently mention research chemicals that are not made for human consumption. Therefore, before purchasing any product for personal use, consult with your doctor or healthcare provider first.

Key Takeaways on Cardarine

  • Cardarine is one of the most popular SARM-like substances for cutting.
  • It is a PPAR receptor agonist which stimulates the expression of genes involved in fat and glucose metabolism.
  • This allows it to effectively switch the body from a glucose-burning to a fat-burning state which promotes rapid fat loss.
Cardarine Summary

Cardarine (GW-501516)

Cardarine is also known to be a PPAR (Peroxisome proliferator-activated receptor) agonist. These receptors are located at various sites in the body, one of which is on muscles. Cardarine binds with PPAR and carries out multiple effects such as reduction in glucose metabolism, promoting fat loss, and enhancing endurance.

Cardarine enhances Lipid metabolization, meaning that it speeds up the rate at which your body takes stored body fat and converts it into energy. Bodybuilders often use this supplement when they are prepping for a contest, as it fits very well into a cutting stack.

Cardarine has been found to lower harmful LDL cholesterol and boost healthy HDL cholesterol.

That means that the drug can potentially help people to avoid suffering from heart attacks, cardiovascular disease, strokes, blocked arteries, and much more besides. It’s rare that performance-enhancing drugs actually promote cardiovascular health and well-being, but that is precisely what Cardarine appears to do, making it very popular.

Cardarine (GW-501516) Overview

⭐️ Top Benefits: Endurance and fat loss
🧪 Form: Liquid, Powder
⌛️ Cycle Length: 6 – 8 weeks
💰 Average Cost: $59.99
❤️‍🩹 Side Effects: Liver toxicity and stomach pain
☢️ Dangers: Hepatotoxicity
📚 Best Stack: MK-677 / Testolone / LGD 4033
PCT Required: No
🧍‍♂️🧍‍♀️Men/Women: Men and Women
🔄 See Results
➡️ Go to the Full review

  • Better recovery
  • Improved fat loss
  • Stomach cramps
  • Liver toxicity

SARMs for Fat Loss

The fat-loss supplement industry is booming, with many of the overhyped, overpriced products delivering zero or barely noticeable results. SARMs and SARM-like substances are different. These coupons really do work, with the caveat that you need to be training hard and dieting diligently alongside their use.

Of all the SARMs that are being sold right now, the three best SARMs for fat loss are Gw-501516 (Cardarine), SR9009 (Stenbolic), and S4 (Andarine). Of these three, Cardarine is the most popular.

Cardarine

Cardarine (GW-501516) is a relatively new drug compared with other steroids, as it was created back in the early 1990s, 1992 to be precise.

Like other types of steroids, the drug initially started out life in the medical industry, as it was created to help treat numerous cancers, and to help reduce dangerous LDL cholesterol in the body.

The drug was developed by Glaxo Smith Kline to prevent the growth and development of cancerous tumors in the body, with the added bonus of helping to regulate cholesterol.

It was soon seen that Cardarine sped up lipid metabolization, which in simple terms means that it speeds up the rate in which your body burns fat and converts it into energy.

As mentioned earlier, Cardarine (GW-501516) is NOT a SARM. SARMs are Selective Androgen Receptor Modulators, whereas Cardarine is actually a Peroxisome Proliferator-Activated Receptor or PPAR for short.

PPARs work in a very similar way to SARMs, with one important difference. They target androgen receptors which help to stimulate glucose metabolization in the muscle tissues. So, the glucose that the muscle cells receive, is instantly converted into energy, rather than being stored in the form of body fat for use at a later date. They also preferentially target fat mobilizing androgen receptors, allowing for expedited fat burning.

Cardarine Benefits

What Is Cardarine (GW-501516)

Fat Loss

Cardarine enhances Lipid metabolization, meaning that it speeds up the rate at which your body takes stored body fat and converts it into energy. Bodybuilders often use this supplement when they are prepping for a contest, as it fits very well into a cutting stack.

Lowers LDL Cholesterol

Cardarine has been found to lower harmful LDL cholesterol and boost healthy HDL cholesterol.

That means that the drug can potentially help people to avoid suffering from heart attacks, cardiovascular disease, strokes, blocked arteries, and much more besides.It’s rare that performance-enhancing drugs actually promote cardiovascular health and well-being, but that is precisely what Cardarine appears to do, making it very popular.

Increased Athletic Outputs

You need to reduce your caloric intake, while at the same increasing your cardio exercise while you are on a Caradine fat loss cycle. However, when people are dieting on fewer calories than their bodies are accustomed to, they can experience energy crashes.

As a result, they feel tired and lethargic, and their strength levels plummet.

Cardarine however, is a drug that not only promotes fat loss, but also helps to increase energy levels.

Athletes discovered that Cardarine worked better than any pre-workout formula currently available at the time as it gave them plenty of energy, which lasted for hours on end.

Cardarine Dosage

If you are a fist time user of Cardrine you should take 10 mg/ml per day over a 4-6 week cycle. From your second cycle onwards you can increase the dosage to 20 mg/ml per day over a 6-8 week cycle. Split this into a morning and evening dose of 10 mg/ml.

Because Cardarine in not a SARM and has no effect on testosterone levels, you do not need to follow a PCT cycle after your cycle.

Cardarine Cycle

Here is a sample Cardarine cycle for an experienced user …

Week One10mg/ml morning

10mg/ml evening

Week Two10mg/ml morning

10mg/ml evening

Week Three10mg/ml morning

10mg/ml evening

Week Four10mg/ml morning

10mg/ml evening

Week Five10mg/ml morning

10mg/ml evening

Week Six10mg/ml morning

10mg/ml evening

Ostarine and Cardarine stack

The most popular Cardarine stack is to combine it with another powerful fat loss agent, Ostarine. As well as speeding up the fat loss, Ostarine will also help to ensure that you don’t lose any muscle mass during your cut. This is a common problem on most cuts.

Here is the ideal dosage for a Cardarine and Ostarine stack:

  • Cardarine – 10 ml/mg per day
  • Ostarine – 15 ml/mg per day
  • Stack length = 8 weeks

So, what sort of results can you expect on this stack?

Results will vary from person to person and will depend on how hard you are training and what sort of caloric deficit you are able to achieve. However, some guys have been known to lose 10 percent of their body weight over an 8-week cycle, without losing any muscle mass.

You can buy a Cardarine and Ostarine stack from Chemyo and is offered in liquid form.

If you choose to purchase from either of these brands, make sure to use the following promo codes to save 10%:

Chemyo: muscleandbrawn10

Cardarine Side Effects

Potential Liver Damage

This is perhaps the most concerning potential side effect associated with this drug. Even though it is much safer than most anabolic steroids currently on the market, one primary concern is that it has been found to damage the liver in studies conducted on mice.

Studies are still ongoing as to whether or not it could possibly cause the same levels of damage to the human liver, but it is certainly worth considering.

Potential Digestive Issues

Another possible side effect of this drug is potential digestive issues.

Some users reported mild stomach aching and stomach cramps, whereas others have experienced bowel trouble, with constipation and/or diarrhea being the most common.

Cardarine Reddit

Reddit features a subreddit called SarmsSourceTalk. This is a great place to hang out in order to get real-time advice from fellow SARMs users. As well as seeing before and after pics, you will also be able to have your questions about compounds such as Cardarine answered.

Is Cardarine Legal?

As of this writing (August 2021), Cardarine is legal for sale in every country around the world except for Australia. You can only get it in Australia with the aid of a doctor’s prescription. In the United States, however, all SARMs, including Cardarine, must be labeled for research purposes only and not for human consumption. That is because they have not been approved for human consumption by the Food and Drug Administration (FDA).

Cardarine For Sale

Cardarine can only be purchased online. There are many websites that sell this compound, but you need to be very careful as to your source. This is totally unregulated industry with many scammers. Only deal with a company that displays certificates of authenticity for every product they sell on their website.

The most reputable companies in the SARMs landscape are:

Final Thoughts on Cardarine

Cardarine is the most potent SARMs-like compound for fat loss. It effectively turns your body into a fat-burning furnace by switching it from a glucose to a fat-burning machine. You should stack Cardarine with Ostarine to expedite your fat loss and prevent the loss of muscle mass.

Still Have Questions?

Drop us a comment down below and one of our expert coaches will respond to it. We’ll also be answering questions on our Instagram!

Contributors

Steve Theunissen

Steve Theunissen | Writer

Steve Theunissen is a seasoned fitness professional with 25+ years of experience. He has multiple certifications from the International Sports Sciences Association, including Certified Personal Trainer, Fitness Nutrition Certification, and Strength and Conditioning Certification. He's a knowledgeable and experienced bodybuilding coach, combining his passion for fitness with his writing skills to educate and inspire. Whether starting out or looking to take training to the next level, Steve Theunissen is the ideal coach to help reach fitness goals.

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John
11 months ago

Thank you for putting this info out there to learn how to get started with SARMs
If the recommend dose is 10 mg/ml per day and the bottle syas its 50ml, does this mean I will need a new bottle every 5 days? I just want to make sure I order enough.
Thanks

Daniel Louwrens BSc PT
10 months ago
Reply to  John

Hi John, that’s not quite correct. Let me help you quickly, if the dose of the bottle is 10mg per ml, and there is 50ml, that means there is (10 x 50 = 500) 500mg of the compound in total. Since your dose could be at 10mg per day, a bottle would theoretically last you (500/10 = 50) 50 days. Hope that helps

Bnsnjsdjj
6 months ago
Reply to  John

That means it’s a 50 ML bottle and 1 ML equals 10mg of Caradine. You have 50 10mg servings so it’s a little more than 6 weeks

J C
1 month ago

I love the info but curious as to if u can take the Cardarine and the ordarine with the mk 66. For some fat loss and muscle growth??

Chemical Structure

Mechanism of Action

Cardarine is also known to be a PPAR (Peroxisome proliferator-activated receptor) agonist. These receptors are located at various sites in the body, one of which is on muscles. Cardarine binds with PPAR and carries out multiple effects such as reduction in glucose metabolism, promoting fat loss, and enhancing endurance.

Class of Compound

PPAR Receptor Agonist

Street Names

Cardarine, GW-501516, Endurobol

Effects

  • Lowers the levels of LDL (bad) cholesterol
  • Improved athletic performance
  • Greater fat loss

Side Effects and Dangers

  • Liver toxicity and damage
  • Stomach pain
  • Not approved for human use

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