SARMs – you’ve heard about ’em, you think you know how they work, and your professional medical advice to your bro at the gym is still limited to “Full send!”.

Sorry to disappoint you my friend, but there is a lot more to these unapproved drugs than meets the eye – or needle.

Using an injectable SARM is quite a risky thing, even if it is one of the existing oral SARMs. It is about as new as you can get, and with limited research, are you making the right decision?

Will you, much like the Ford Pinto, explode once you are rear-ended with a minor inconvenience/needle? (If you don’t get that joke, Pinto’s exploded when they got rear-ended)

Well let’s try to avoid that first-pass effect and you and I take a stroll down to the pharmacy for some rubbing alcohol – let’s discuss Injectable SARMs – Good or Bad?

What are SARMs (Selective Androgen Receptor Modulators)?

Before we can delve into the beautiful world of research chemicals and your extremely concerned mother(s), we need to identify what the hell SARMs are in the first place.

Take your mind back to the early 1900s and imagine you’re a doctor trying to help a patient gain some muscle. The problem is, this guy has fricken AIDS, and he is losing mass by the day.

Well, you did what old Ronnie did, and you get some “Test and Dbol” and boom, the guy’s gaining some weight. Sure, his cholesterol is wrecked, but it was (overall) not a bad idea.

Your next patient happens to be a lady. Shit, you can’t give her Test and Dianabol – so, what do you do? Well, doctors and medical engineers developed something called SARMs or Selective androgen receptor modulators.

These SARMs will not bind to all the Androgen receptors in the human body, meaning you can expect far fewer side effects. They are tissue selective and remove a lot of the safety concerns we have with Steroids [1].

That said, they aren’t as powerful. But, you can still see some good results. SARMs have then come down from their medical usage into the world of fitness where you and I can now do our research…

While clinical trials are still being done on SARMs, we know that at a higher dose, these compounds can help with fat loss, muscle growth, and even longevity.

So, in summary. They are not Steroids, they simply act upon the same area as Steroids and do some of the same stuff. Kinda how both trucks and cars fill at the same gas station, but still massively different vehicles.

What are Injectable SARMs?

Well, as the name suggests, these are SARMs that you do not take orally (or rectally – please for the love of CBum do not do that), but you inject them. This is an extremely new thing, and to be honest, you rarely hear about anyone doing it.

Now, injecting drugs or substances is nothing new. Subscription medication can be injected, and Steroids are mostly injected. So, the actual mechanism of injection isn’t bad, however, when you’re using a new compound like a SARM and a new means of administration, your risk of danger skyrockets.

Bold claim, so, let’s see if there’s any research on these bad boys – maybe there are potential benefits! (Google intensifies…)

Well, there’s not. Using SARMs via an intramuscular injection has not been tested, hell, SARMs have not even been tested that much. Injectable SARMs are modified SARMs to be able to work when injected, but they just haven’t been studied.

Are Injectable SARMs Bad?

Define “bad”. Bit hard ain’t it? Well, they certainly aren’t awful. While more research is needed, there is some folk who have used them in the past – like Derek from More Plates More Dates.

The only problem with these injectable SARMs is being potentially dangerous ingredients – seeing as the product needs to be suspended in something. Looking at some of the brands that list these types of SARMs, like Behemoth Labz, don’t list what the solvent or suspension liquid is.

This does raise some concerns. Certain solvents or carrier oils carry fewer side effects than others, so most guys want to know what the method of delivery is. Currently, there are no proven negative side effects, however, I’d stick to the oral SARMs.

Are Injectable SARMs Good?

As any gym bro would tell you, bioavailability does matter. By using an oral compound, it needs to survive the first pass effect first. This is the process in which the liver needs to digest the compound in question.

This is why oral SARMs and Steroids don’t have perfect bioavailability. That said, certain products have great bioavailability despite having to survive the first pass – S23 for instance. S23 has been studied and has a bioavailability of more than 90% in animals [2].

That said, an injectable SARM would have higher bioavailability – and as an even bigger benefit, it doesn’t pose liver toxicity! Because of the first pass, you’re more likely to cause damage to the liver with oral SARMs and Steroids.

So, the biggest benefits there are to injectable SARMs are higher bioavailability and less/no liver damage.

What are the Side Effects of Injectable SARMs?

• Any regular side effects associated with the drug in question
• Risk of infection at the injection site, especially if you do not use sterile needles
• Scarring the muscle you inject into, or even muscle tear(s) if you inject wrong and train the muscle immediately
• Could have other adverse effects on health that we do not know of yet

Do they differ from Injectable Anabolic Steroids?

Anabolic Steroids have been used to improve athletic performance for several years. Other body-building products have also been injected like L-Carnitine which is one of the best fat-loss supplements on the market.

Steroids will bind to every Androgen Receptor they can find and cause a biological change, thus, Steroids can lead to prostate cancer [3] since the prostate will also grow.

SARMs differ from Steroids because they are selective – hence the name. This takes out most of the serious safety concerns but still grants you some of the potential benefits that Steroids do.

So, no, they are not the same as injectable Steroids, but they do act upon the same receptors – still massively different drugs.

Are Oral SARMs Good?

Oral SARMs are the main form you find SARMs – whether it be tablets, powders, or liquids. These will all lead to some increase in lean muscle mass, and some will even help with fat loss as well.

SARMs are often misjudged as toxic products, but they simply aren’t. They do work, there is some research to show this. There is a ton of anecdotal evidence to show it does as well. That said, there is still research to be done since the androgenic activity of these compounds has not been fully established, nor have the other health adverse effects either.

Can you Inject Oral SARMs?

No. No, thousand times no. Injectable SARMs are highly specific drugs that have been designed to be the way they are. First off, the compounds differ from one another. Let’s look at two of the same compounds, except one is oral and one is injectable.

These are the same compounds but are different because of one simple methyl group that is added. Not a big difference hey? Well, this is Masteron vs Superdrol, two Steroids that differ massively from one another. Masteron is mild, Superdrol will cause liver damage within 5 weeks…

Further from this, injectable compounds need to be dissolved first. Then, they need to be suspended in something and then placed in a sterilized vial.

Do not inject oral SARMs.

What is Magnalone?

Because SARMs have such a short half-life, they have limited use. Once the active compound is no longer in your blood, it won’t work…

Magnalone is a version of LGD 4033 that was developed to have a longer half-life, and with the extension, you have more of the active compound to do its work.

It is an LGD 4033 that has an ester attached to it so you only need to inject it every 3 – 4 days to keep stable plasma levels. This is the most famous of the injectable SARMs but remains one of the unapproved drugs by the FDA.

Online forums have a bit of info on this compound, however, nothing credible or in line with “medical services”.

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Injectable SARMs vs Injectable Peptides

Injectable Peptides are not the same as SARMs – in fact, they are massively different. First, unlike SARMs, they do not pose any androgenic activity. They do not act on the same tissue in the body, and they are way more researched.

Peptides can be used to increase muscle growth, skin quality, weight loss, and even sexual function. Some have even been approved for medical treatment at HRT clinics such as Evolve Telemed.

SARMs would make it easier to build muscle, yes, but will also have a lot more side effects – and more severe.

Are Injectable SARMs Legal?

SARMs are legal to purchase under the nomenclature of “research chemicals” – and they cannot be sold “for human consumption”. This will remain this way until further research has been done to pinpoint the health effects these compounds have.

Conclusion: Are Injectable SARMs Good or Bad?

Overall, they probably aren’t “bad”, however, way more research is needed. Most vendors cannot even identify what they use as solvents or suspension liquids – and just so btw, some people are allergic to certain oils.

This poses a health and danger risk, and for those reasons, I won’t be taking an injectable SARM anytime soon – I’ll take some TUDCA to avoid liver toxicity… maybe some Glutathione too.