Excessive hair loss can be devastating to many. Waking up with a handful of hair scattered onto your pillow possibly feels like a nightmare.
Experiencing hair fall while combing your hair would equally make you anxious and give chills at that moment.
Head brimmed with dense hair plays an integral role in modern-day aesthetics.
To cope with medical conditions, such as Androgenic Alopecia characterized by hair loss in both men and women and which is also equivalent to Male pattern baldness in men, some drugs for topical treatment like RU 58841 have been developed.
This article is a RU58841 review, and I will make sure to include everything you need to know, such as all the benefits, the scientific evidence behind RU58841 for hair loss treatment, dosage, and cycling guidelines, as well as any adverse effects that it may trigger.
- Excessive hair loss can be distressing, and the article discusses RU 58841 as a potential treatment for hair loss.
- RU 58841 is a non-steroidal anti-androgen (NSAA) topical solution originally developed for hair loss treatment.
- It works by competing with Dihydrotestosterone (DHT) to bind to androgen receptors in hair follicles, maintaining DHT levels within normal limits and promoting hair growth.
- RU 58841 is not FDA-approved and is only allowed for research and scientific studies, not for human consumption.
- Users have reported positive results with RU 58841, such as improved hair growth and the potential reduction of androgenetic alopecia (male pattern baldness), but its long-term safety is still a subject of concern.
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What is RU 58841?
RU 58841, a topical solution for hair loss, belongs to the class of drugs, called non-steroidal anti-androgen (NSAA) (1).
It was first invented and put into research trials by a French company, called Roussel Uclaf.
Originally, it was thought that RU58841 could potentially cure prostate cancer, but as more research evidence piled up, it was evident that RU58841 could prove a “magical pill” for hair loss treatment.
Due to some financial constraints, French scientists were unable to use RU 58841 for any more research. However, it was soon purchased by a company called Prostrakan who renamed the drug to PSK-3841.
While the new owners did put RU 58841 into clinical trials, the drug never reached phase 3 of the study possibly either due to financial reasons or regulatory restrictions.
How Does RU58841 Work?
Before really digging into how RU58841 would work in the body, it is important to understand what possibly triggers hair loss, particularly in male pattern baldness (MPB) (2).
Dihydrotestosterone (DHT), a by-product of testosterone metabolism, is known to act as a potent agonist of Androgen Receptors located in hair follicles.
This results in the weakening and shortening of hair follicles, eventually leading to excessive hair fall (3).
This is where RU 58841 acts magically!
Unlike other non-steroidal anti-androgen (NSAA), such as the oral finasteride group, which downregulates the production and release of Dihydrotestosterone (DHT) and testosterone levels, RU 58841 rather acts as a strong potent agonist of Androgen receptors located in hair follicles (4).
Now you might be thinking why was there a need for RU 58841 to be developed if another topical treatment, such as the finasteride group was working well as a hair loss treatment?
The answer to this question is simple. We talked about how these other treatments were lowering the DHT levels, and DHT and testosterone levels need to be kept optimal, mainly in males to ensure lean muscle mass and improve libido.
For that reason, alternatively, RU58841 competes with Dihydrotestosterone (DHT) as the former binds more strongly with the specific Androgen receptors (AR) located surrounding the scalp hair receptors.
This ensures that DHT levels are kept within normal limits, and at the same time, the hair growth cycle is not inhibited.
Besides, some research studies also suggest that RU58841 stimulates new hair follicles to convert to anagen follicles by entering the anagen phase.
Besides, RU58841 for hair loss also gives sufficient time for damaged hair follicles to regrow rather strongly.
Where to Buy RU 58841?
Before we can talk about the trusted and authentic places to buy RU58841, you need to know that there are currently 2 forms of this drug available.
Either you can buy the prepared solution which you will just have to apply directly using the dropper or you can buy the raw powder form of RU58841.
In the latter, you will have to prepare the solution yourself by closely following the instructions listed on the bottle.
Because this hair loss treatment is strictly regulated and not FDA-approved, you will not find many trusted vendors or sellers selling RU58841.
If you already know any trusted local vendor, make your purchase straight away.
Perhaps you may also search Amazon products and based on reviews and effectiveness, make your decision. We highly recommend, Pure Rawz.
Important to mention, Pure Rawz is a well-renowned RU58841 supplier and has been in the game for a long now.
Benefits of RU58841?
After reading how RU 58841 works, I am sure you must have an idea about how the compound is going to help you immensely if you are a part of the hair loss community!
Firstly, what’s amazing about RU58841 is how quickly and swiftly it acts. Perhaps this is because it is applied topically and takes no time to reach scalp hair receptors.
Because RU 58841 initiates human hair production, most users of the compound suggest that within a few weeks, they were able to combat hair loss as their hair growth just continued well enough.
A controlled study also suggested that RU 58841 allowed the blood flow to damaged hair follicles so that they could enter the hair regrowth stage.
Not only this, some before and after results of users suggest that RU 58841 helps you give a straighter hairline and minimize your un-hairy patches as much as possible.
Due to the immensely positive results of this non-steroidal anti-androgen (NSAA) drug in aiding hair loss prevention, some users have reported getting rid of androgenetic alopecia completely, in particular, male pattern baldness (MPD) (5).
Although unclear, there is some evidence that suggests RU 58841 manages skin irritation and acne-related problems.
However, more research is required in this area before this hypothesis can be confirmed.
Before we go any further, you should note that if you are already planning to use the drug to prevent hair loss, you should know that you might experience significant hair loss at the start before your hair follicles can enter the second growth cycle and make you look younger and smarter than ever!
Is RU 58841 Legal?
RU 58841 is not declared legal and is not approved by the FDA, unlike other hair loss treatments.
Therefore, it is not allowed for human consumption at all, as it is strongly regulated, and your healthcare provider may not be able to prescribe it for personal use.
It is only allowed to buy RU 58841 if your purpose is for research and scientific studies.
Due to its regulatory status, the purchase of RU 58841 is limited to research and experimental purposes, and it should not be used without careful consideration and adherence to legal restrictions.
It’s important to consult with a medical professional before considering its use, and individuals should be aware of the legal and ethical implications surrounding its acquisition and application.
Who Should Use RU 58841?
Anyone wanting to cure themselves of Androgenic alopecia once and for all should use RU 58841.
If you are suffering from male pattern baldness (MPB), RU 58841 is still your best shot available in the market.
This drug can come in handy as well if you have any skin-related problems, but I wouldn’t recommend using it for that specific purpose.
How to Use RU 58841?
This is a very important question and needs to be answered in a detailed way because, unlike other medications, it needs to be applied topically.
First of all, you have to strictly use it either after showering or washing your head and then drying it. This is because there is less sebum accumulation at that time.
Once you have the bottle of RU 58841 in your hand, closely read the instructions before applying it anyway.
As per your dosage requirements, fill the dropper up to the optimal limit. Then, try to apply the RU 58841 directly to your scalp, particularly the areas that are devoid of hair.
Spread it around the patchy areas firmly so that your balding scalp grafts absorb the solution well. You may use your fingers as well for maximal spread.
Ru58841 Side effects
The good thing is that RU 58841 doesn’t downregulate the DHT levels, therefore typically it is not known to cause any adverse effects.
Besides, not many human clinical trials have been performed so it is difficult to predict the exact nature of side effects.
But because RU 58841 is a strong agonist of androgen receptors, it may block the other androgen receptors as well besides DHT.
So, if we consider pharmacodynamics, you may experience decreased libido and erectile dysfunction. But clinical trials so far suggest otherwise.
Other mild side effects include fatigue, headache, dizziness, mood disorders, and blurred vision.
The typical initial dosage requirement of RU 58841 for hair loss treatment is 50mg per day applied topically.
Considering the experiences of people, most users witnessed significant changes with this dose, and their hair loss was gone!
If you don’t see the results with this minimal yet optimal dose, you may try out either 75mg or 100mg per day but this is only in extreme cases.
Perhaps to see better and swift results, you need to keep applying the RU 58841 solution for a longer duration.
Make it one of your daily habits, and be persistent at it! As long as you keep applying, you will see the outcome of no hair loss sooner or later.
I am sure that there is one question that you might have at this point, which is:
How do you know whether RU 58841 for hair loss treatment is working?
The answer to this will be based on your judgment initially. Try counting how many hairs you approximately lose each day while combing.
This might give you a rough estimate measure over time.
RU 58841 Stack
The only potential stack of RU 58841 is with Minoxidil.
While we know how RU 58841 works by blocking DHT from binding to the androgen receptors located in hair follicles, Minidoxil works by ensuring optimal nutrients and blood flow to the scalp (6).
Thus, hair regrowth is strong and hair loss is limited to a significant extent.
Together both hair loss treatments can operate synergistically in your head to help you tackle male pattern baldness (MPD).
Not only this, but you will also end up having thick, dense, and raven hair after using the RU 58841 and Minoxidil stack.
RU 58841 Experiences
Time to read some personal experiences of people before you can decide on this NSAA.
“This is crazy but it’s only been about 1.5 weeks since I started, kinda just stopped paying attention to the process, then just recently, noticed that my head feels more bristly.
It seems there are some little clear hairs showing up that can’t yet be seen with the naked eye but can be felt. I’m excited to see what happens by the end of this bottle!”Mike F says,
“Great product, it actually works. The only thing that worries me is long term safety issues. Other than that, it is really miraculous that it works after having failed with dutasteride.”Carlos says,
“I’m using RU58841 about 2 months and I have very good results now! I have 2 more bottles and we will see next results.”Toni Radic left a 5.0-star review and said,
Best Time to Take RU 58841
As I stated earlier, the ideal time for applying the RU 58841 solution is strictly after showering or washing your head and then drying out well.
This, in turn, will improve the efficiency of the RU 58841, and you will see desirable results within no time!
RU 58841 Pricing
While the pricing may vary depending on the brand, the competitive price range is somewhere between $40 to $60.
Depending upon the volume you buy, you may be billed higher than this.
RU 58841 vs Minoxidil
|Mechanism of Action||Androgen Receptor Blocker||Stimulates blood flow to the scalp||Androgen Receptor Blocker||5-alpha-reductase Inhibitor|
|Brand Name||RU 58841||Rogaine||CB-03-01||Propecia|
|Side Effects||Limited data on side effects||May cause skin irritation; otherwise, generally well-tolerated||Expensive; mild action||Sexual problems, weakness, sluggishness|
|FDA Approval||Not FDA approved||FDA approved||Not specified||FDA approved|
|Common Use||Hair loss treatment||Hair loss treatment||Hair loss treatment||Hair loss treatment|
Minoxidil, which is more popularly sold by its brand name Rogaine, is a potential antihypertensive vasodilator.
It stimulates the blood flow to the scalp, thus ensuring a proper nutrient and oxygen supply.
This allows the proper growth cycle of the hair follicles and keeps them in the anagen phase for longer.
While Minoxidil helps you manage androgenic alopecia, it also makes sure that your hair is thicker, denser, and smoother.
RU 58841 vs CB-03-01
CB-03-01 is also an NSAA just like RU 58841, and works in quite a similar way to the latter by blocking the androgen receptors.
It also doesn’t cause any major side effects and acts very mildly. Perhaps it is quite expensive amongst the hair loss treatments, and possibly least used as well.
RU 58841 vs Finasteride
While the Finasteride group also belongs to the category of NSAA, it is an approved drug by the FDA and is sold under the brand name Propecia.
Finasteride works by inhibiting the enzyme called 5-alpha-reductase, which prevents the formation of DHT from testosterone (7).
This results in lower DHT levels while higher testosterone levels, and thus it doesn’t bind with the androgen receptors located in the hair follicles.
While Finasteride may seem ideal to you as a hair loss treatment, it comes with a whole set of adverse effects. Sexual problems top the list accompanied by weakness and sluggishness.
Does RU 58841 regrow hair?
Yes, it does!
RU 58841 aids in cellular recovery and reverts the damaged hair follicles into the anagen follicles.
Does RU 58841 work?
RU 58841 works by blocking the androgen receptors so that DHT can not bind to them. This potentially cures medical conditions like Androgenic alopecia and Male pattern baldness (MPD).
Is RU 58841 a pill?
No! RU 58841 is not available in pill form. You will only find the drug in either the solution form or raw powder form.
Is RU 58841 a DHT blocker?
In simple terms, RU 58841 blocks the DHT from binding to the androgen receptors located in the hair follicles.
Why is RU 58841 not FDA-approved?
RU 58841 couldn’t complete the phase 3 clinical trials, mainly because of less budget. Thus, the FDA hasn’t approved it yet.
What is the half-life of RU58841?
The pharmacokinetics suggest that RU 58841 has an extremely shorter half-life of less than 1 hour.