15 TRT Stats and Facts (Testosterone Replacement)

TRT or Testosterone Replacement Therapy is a new medical therapy that can save lives. With so many gurus online let's discuss the medical facts about TRT.

Key Statistics about Testosterone Replacement Therapy

  1. In 2017, 4.7 active male military members out of every 1000 filled a prescription for testosterone replacement therapy.
  2. In 2017, only 44.5% of active male service members who received testosterone replacement therapy met the AUA clinical guidelines.
  3. Between 2022 and 2027, the testosterone replacement therapy market is expected to grow at a compound annual growth rate (CAGR) of 3.38%.
  4. Experts predict that the testosterone replacement therapy market to grow by a whopping USD 439 million.
  5. In the US hospital segment, testosterone replacement therapy was valued at USD 1, 148.09 million in 2017 and is expected to grow through 2023.
  6. The North American market is expected to contribute 57% of the total testosterone replacement therapy growth market.
  7. In The US alone, more than 43% of women and 31% of men suffer from some form of sexual dysfunction or erectile dysfunction.
  8. Testosterone replacement therapy saw a 500% increase in sales growth between 1991, and 2001.
  9. The levels of testosterone in adult makes declines between 1% and 2% yearly.
  10. By the age of 80 years old, the testosterone levels of 50% of males or more, sits within the hypogonadal range.
  11. 50% of postmenopausal women experience sexual dysfunction.
  12. According to the website of government statistics, at the end of March 2023, there were 69 studies currently in progress looking specifically at testosterone replacement therapy.
  13. Asian-Pacific is the fastest-growing region for testosterone replacement therapy, growing at the fastest CAGR between 2018-2028.
  14. The biggest multinationals in the testosterone replacement therapy industry are Endo Pharmaceuticals, AbbVie Inc, Pfizer, Eli Lilly, and Company, and Bayer AG.
  15. Depending on several factors, including the type of medication, insurance, and dosage, testosterone replacement therapy costs between $1,650 to $3, 200 annually. (1) (2) (3)

1. Testosterone Replacement Therapy and the Military

The testosterone replacement therapy studies conducted by the military to date have been limited to “active service members” hence the comparison to the general adult male population should be regarded with caution. Additionally, the military itself also expressed and concluded that the medical history of many of the men who participated may be inaccurate or, at the very least, incomplete.

1. In 2017, 4.7 active male military members out of every 1000 filled a prescription for testosterone replacement therapy.

44.5% of military men receive testosterone treatment which the military found to be significantly less than what one would expect to see among the general population. Researchers suggested, however, this could be due to the age discrepancies of the study participants.

2. In 2017, only 44.5% of active male service members who received testosterone replacement therapy met the AUA clinical guidelines.

According to military statistics, 3 out of every 1000 active service members are being or have been inappropriately treated with testosterone therapy. As such, they are experiencing higher rates of adverse side effects, including sleep disorders like sleep apnea, reduced quality of life, and even urinary tract symptoms. (4)

The testosterone replacement therapy market is competitive, and with the continued rise in awareness of health conditions like sexual dysfunction, the market is expected to continue to grow. Emerging regions like Asia-pacific are pouring in millions to research and development and are helping to drive the testosterone replacement therapy global market growth.

1. Between 2022 and 2027, the testosterone replacement therapy market is expected to grow at a compound annual growth rate (CAGR) of 3.38%.

Due to the boom in testosterone replacement therapy, market growth is expected to continue to rise partly due to the benefits testosterone therapy has on sexual function, quality of life, and lean muscle mass.

2. Experts predict that the testosterone replacement therapy market to grow by a whopping USD 439 million.

Additionally, the testosterone replacement therapy market in ther US alone is estimated to climb to USD 439 million. With low testosterone levels, bone density, and erectile function issues, it’s no wonder the industry is investing heavily in these areas.

3. In the US hospital segment, testosterone replacement therapy was valued at USD 1, 148.09 million in 2017 and is expected to grow through 2023.

Hospital market growth will continue to rise, primarily based on the distribution channels within the broader medical field. In 2022, the hospital segment had its largest market growth. A significant factor in this increase is that outpatient and inpatient treatments now comprise part of the hospital segment.

4. The North American market is expected to contribute 57% of the total testosterone replacement therapy growth market.

It’s no surprise that North American market growth will contribute nearly 60% of the total testosterone replacement therapy market. With many of the biggest companies, like Pfizer and AG Bayer, based in the US, the future looks bright when it comes to treatments for various conditions like cardiovascular disease, prostate cancer, and low testosterone levels.

5. Asian-Pacific is the fastest-growing region for testosterone replacement therapy, growing at the fastest CAGR between 2018-2028.

Similar to North America, the presence of major players within the industry continues to drive market growth and share in the Asia-Pacific region. Japan, China, and Taiwan are all home to some of the leaders in testosterone replacement therapy and testosterone treatments. (5)

In terms of global geography, the testosterone replacement therapy market has been split into four distinct segments.

  • North America
  • Europe
  • Asia-Pacific, and
  • The rest of the world or (ROW)

58% of the market has been cornered by North America, with the US and Canada leading the way when it comes to testosterone therapy. This is primarily due to both governments raising awareness about health conditions such as prostate cancer, bone density, heart disease, erectile function, and low testosterone.

1. The biggest multinationals in the testosterone replacement therapy industry are Endo Pharmaceuticals, AbbVie Inc, Pfizer, Eli Lilly and Company, and Bayer AG.

These are the major players helping to drive the market growth in the testosterone replacement therapy industry. Big names like Pfizer and AbbVie Inc are investing millions in research and development on products like testosterone gel, hormone replacement therapy, and a variety of other testosterone products.

2. Testosterone replacement therapy saw a 500% increase in sales growth between 1991, and 2001.

The Food and Drug Administration (FDA) had little oversight during the early to late 90s, and as such, sales grew by a whopping 500% between 1991 and 2001.

3. According to the website of government statistics, at the end of March 2023, there were 69 studies currently in progress looking specifically at testosterone replacement therapy.

In recent years testosterone replacement therapy has boomed, which is confirmed by the fact there are currently 69 ongoing studies looking at conditions like testosterone deficiency, low testosterone, secondary hypogonadism, androgen deficiency, and other androgen deficiency syndromes.

4. Depending on several factors, including the type of medication, insurance, and dosage, testosterone replacement therapy costs between $1650 to $3200 annually.

It’s difficult to provide exact numbers for how much testosterone replacement therapy and testosterone treatment actually costs due to varying factors. Types of medication and insurance coverage are just two of the many factors that contribute to the overall affordability and feasibility of testosterone replacement therapy use. (6) (7)

4. Testosterone Replacement Therapy and Sexual Function

For both men and women, low testosterone levels can have serious impacts on your sex life and mental health. Testosterone replacement therapy is a way to help renew the body balance helping you to feel fresh, vibrant, and reinvigorated. Testosterone replacement therapy is not safe and effective but can also help to boost quality of life, improve sexual function, and overall health and well-being.

1. In The US alone, more than 43% of women and 31% of men suffer from some form of sexual dysfunction or erectile dysfunction.

Staggering numbers show that 43% of women and 31% of adult men experience sexual function issues along with decreases in sexual desire far outside the normal range. Prescribing testosterone with mild adverse events is proving to be a big hit for women and middle-aged men.

2. 50% of postmenopausal women experience sexual dysfunction.

Postmenopausal women were shown to be amongst the highest groups experiencing sexual dysfunction, with 50% of them experiencing reduced sexual desire.

3. The levels of testosterone in adult makes declines between 1% and 2% yearly.

Lower levels of bioavailable testosterone decline between 1 and 2% annually on overage, showing that testosterone deficiency is a genuine concern among adult men. Testosterone therapy prescription is high in males, especially as the total testosterone levels continue to fall as we age.

4. By the age of 80 years old, the testosterone levels of 50% of males or more, sits within the hypogonadal range.

Male hypogonadism, testicular dysfunction, and primary hypogonadism are major concerns for nearly 50% of all male patients. Testosterone-boosting medications that meet clinical practice guidelines are being developed to help mitigate symptoms associated with these conditions. (8) (9) (10) (11)

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https://www.technavio.com/report/testosterone-replacement-therapy-market-industry-analysis?nowebp

https://www.aafp.org/pubs/afp/issues/2006/0501/p1591.html

https://www.mordorintelligence.com/industry-reports/testosterone-replacement-therapy-market

https://www.health.mil/News/Articles/2019/03/01/Testosterone-Replacement-Therapy?type=Fact+Sheets

https://www.technavio.com/report/testosterone-replacement-therapy-market-industry-analysis?nowebp

https://www.technavio.com/report/testosterone-replacement-therapy-market-industry-analysis?nowebp

https://www.aafp.org/pubs/afp/issues/2006/0501/p1591.html

Metzger, S., & Burnett, A. (2016). Impact of recent FDA ruling on testosterone replacement therapy (TRT). Translational Andrology And Urology, 5(6), 921-926. doi:10.21037/tau.2016.09.08 https://tau.amegroups.com/article/view/12198/html

Elliott J, Kelly SE, Millar AC, et al. Testosterone therapy in hypogonadal men: a systematic review and network meta-analysis BMJ Open 2017;7:e015284. doi: 10.1136/bmjopen-2016-015284 https://bmjopen.bmj.com/content/7/11/e015284

Margo K, Winn R. Testosterone treatments: why, when, and how? Am Fam Physician. 2006 May 1;73(9):1591-8. PMID: 16719252. https://pubmed.ncbi.nlm.nih.gov/16719252/

Elenkov, A., Al-Jebari, Y., Giwercman, Y. L., & Giwercman, A. (2020). Testosterone replacement therapy in men who conceived with intracytoplasmic sperm injection: nationwide register study, European Journal of Endocrinology, 182(4), 423-428. Retrieved Apr 16, 2023, from https://doi.org/10.1530/EJE-19-0734

Contributors

Brenton Barker

Brenton Barker | Writer

Brenton is a highly qualified sports coach with over 20 years of experience working with professional athletes. With a degree in sports coaching and experience in prominent positions, including Head Advisor to the Japanese Government Sports Institute and Manager & Head Coach to Australia's Governing Sporting Body. Currently, he consults with several professional athletes and sporting organizations, sharing his expertise to help them reach their full potential.

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