PT-141: Best Peptide for Erectile Dysfunction

Erectile dysfunction is one of the most common sexual disorders experienced by men. With many treatments, is PT-141 the Best Peptide For Erectile Dysfunction?

Class of Compound


Mechanism of Action

PT-141 is an analog of the alpha-melanocyte stimulating hormone. It binds to melanocortin receptors, especially MC3R and MC4R, which stimulate the hypothalamus sending action Potentials to the anterior pituitary, thereby increasing libido.

Street Names



Increases sexual arousal, helps improve sexual performance, fat burn

Side Effects and Dangers

nausea, slight headaches, injection site rashes

Chemical Structure

Getting diagnosed with any sexual disorder can be equally disturbing for both men and women. The repercussions of being diagnosed with the latter expand beyond the medical horizon because it also puts a heavy toll on your mental well-being, emotional state, and personal life. 

Perhaps sexual disorders such as erectile dysfunction and premature ejaculation in men, while sexual hypoactivity in women is one of the major contributors to divorce in marriages. 

Although the risk of experiencing sexual disorders such as erectile dysfunction increases with age, young people are also susceptible to getting diagnosed with sexual disorders in this era due to many lifestyle changes in the recent past. 

While many medications have been developed in the market targetting both male and female sexual problems, such as Viagra and Cialis, there is always a scope for more research and development in this field. 

Today we are talking about PT-141, a synthetic peptide that has been introduced into the market to potentially treat erectile dysfunction and improve the sexual life of both men and women. 

Let’s review PT-141 and everything related to it and if it is really the Best Peptide for Erectile Dysfunction.

What is PT-141? 

Best Peptide for Erectile Dysfunction

PT-141, also referred to as Bremelanotide, is a synthetic analog of the alpha-melanocyte stimulating hormone (1). Due to structural resemblance, it acts as a potent agonist of melanocortin receptors located in different areas of the central and peripheral nervous system. 

Being a synthetic derivative of Melanotan II, it was initially developed for skin pigmentation by stimulating melanocytes to induce melanogenesis. However, it soon gained enough traction as a potential therapeutic drug to treat ED in men and sexual hypoactivity in women by elevating pleasure levels. 

Since its development, a handful of clinical trials have been performed, and because of its effective results, it has also been called “female viagra.” 

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How Does PT-141 Work?

As an analog of the alpha-melanocyte stimulating hormone, it binds to Melanocortin receptors, especially MC3R and MC4R, which are expressed primarily in the central nervous system (2). 

The subsequent binding of PT-141 with melanocortin receptors stimulates the hypothalamus, sending action potentials to the anterior pituitary gland (3). As a result, one experiences enhanced sexual desires by having better erections and increasing sex drive (libido). 

One of the major reasons why PT-141 can be considered as an alternative to existing medications such as Viagra and Cialis is because PT-141 works via stimulating the central nervous system, unlike the latter, which works by inhibiting PDE-5, which increases the blood flow to the penis and triggers erection in men (4). 

Benefits of PT-141

Bremelanotide, commonly known as PT-141, is renowned for its tremendous benefits in the sexual life of both women. The sex peptide is all you need if you have erectile dysfunction and hypoactive sexual life. 

It is reported that PT-141 aids in enhancing libido in men while ensuring that the affection for your partner is never lost in the dust by increasing sexual arousal (5). 

The sex peptide help improve the sex drive and revive the old memories associated with it. 

Besides, young couples are often subjected to depression and anxiety due to various factors. Previous trauma and medical conditions are some of them. However, with PT-141, you get the chance to improve your sexual performance (6). 

Additionally, people often experience a boost in their confidence and self-esteem after PT-141 supplementation. 

Medically, PT-141 aids in reinforcing pelvic muscles and bladder control and might aid in mitigating the risk of developing cardiovascular disorders. 

The sex peptide is also seen to increase calorie and fat burn. Thus PT-141 can help you in bodybuilding and reducing excess subcutaneous fat. 

With numerous such benefits, it makes sense why more and more people are opting for PT-141. 

Best Peptide for ED + PT-141 Review

Is PT-141 Legal? 

Luckily, the answer to this question is yes!  

PT-141 is indeed approved by the FDA for treating low sexual desire in women. With all the phases of clinical trials completed, PT-141 seems to have a good long-term safety profile (7). 

However, please note that the drug can’t be used as a potent initiator of erection in terms of legal standards. Note that this doesn’t mean the drug is incapable of doing so. 

The drug can be easily purchased online for research and scientific investigation without repercussions. 

Who should use PT-141?

PT-141 isn’t just for anyone looking for a way to improve their sexual life. Although the drug may sound phenomenal to many, it has some serious side effects. 

Therefore, the FDA approved PT-141 as a potential treatment for premenopausal women suffering from Hypoactive Sexual Desire Disorder (HSDD) (8). However, the drug also favors normal erectile functioning in men with a favorable safety profile. 

Couples undergoing low libido and decreased sexual intimacy can also use PT-141 for improvement. 

How to Use PT-141

It is convenient to use PT-141 as it is available in various forms. PT-141 can be administered via subcutaneous injections, nasal sprays, pills/oral medication, or even creams. 

After 30 minutes of administration, PT-141 usually starts to kick in. 

PT-141 Dosage & Cycle

Many often misinterpret the dosage of drugs and end up experiencing nasty side effects associated with the specific drug. Therefore, you must know the right dose and cycle before starting the supplementation. 

The most common dosage of PT-141 is 1.75 mg taken before sexual activity. For women suffering from HSDD, it is highly advised to limit the administration of PT-141 to no more than once a day, with a maximum of 8 times per month. 

Generally, 1 to 2 mg of PT-141 is primarily recommended. You can also reduce the dose and experience its similar effects. 

PT-141 User Reviews and Experiences  

Customers who have already been through the supplementation of the drug give you an insight regarding the drug and whether it’s worth the money you’re spending on. 

For PT-141, one of the users said,  

“I have used a combination of PT-141 and 50mg Cialis and had an on/off erection for 3 days.

Had the most amazing sex session that lasted a few hours.

I also suffer from ED due to secondary hypogonadism. I think it depends on where you get the PT-141 from and also the dosage – I used 2mg.

PT-141 was first discovered when scientist Mac Hadley’s generous volunteered of himself to inject a double dosage of MT2 and ended up with an 8hr erection.”

Another user said,  

“I’ve tried it and heard other people swear by it. Personally, I get a bit hot and flushed but don’t have a huge effect. That said, I’m definitely not hypoactive, and I’ve had no negative side effects, so I’d say definitely try it.”

One of the users was disappointed as he left a comment, 

“I’ve tried PT-141 3 times but not the dosing your stating here. Ive gone up to 1mg but the nausea was extreme. Has anyone else experienced that? If so, is there away around that?”

Best time to take PT-141 

It is recommended to take PT-141 if you anticipate any sexual activity. It is advised to administer PT-141 approximately 45 minutes to an hour before the sexual intercourse. The sex peptide takes 30 minutes for the effects to kick in. 

Side effects of PT-141

It is not uncommon to suffer from mild side effects with PT-141 administration; at a 1.75 mg dose, you can experience nausea, slight headaches, injection site rashes, and skin flushing. These are fairly common and can be treated with well-deserved rest. 

Nonetheless, PT-141 can also lead to some adverse effects requiring medical emergencies. This includes raised blood pressure, extreme nausea, arthralgia, or local hyperpigmentation. It would help if you got in touch with your doctor. 

Where can I buy PT-141? 


Pure Rawz is one of the best vendors to look for when buying peptides or SARMs. PT-141 is one of the popular sex peptides to be sold out by the brand. 

Currently, the drug is only available in 10 mg dosage.

Although the price of $72.98 to $94.48 might sound a bit expensive to some and not worth the money, the product is of the highest quality, as proven by its customer review. With its secure checkout, third-party testing, and free delivery of over $100, pure rawz indeed knows how to gain user trust.

Buy Now

Is PT-141 Legit? 

PT-141 has been gaining popularity like no other sex peptide. The drug definitely works. Many couples have reported having improved sexual life after PT-141 administration. 

Clinically, PT-141 can treat serious disorders such as HSDD in premenopausal women. These disorders are often one of the biggest causes of depression and low confidence. With PT-141, you have got the chance to beat it. 

However, make sure you strictly abide by the right doses. A high dosage of PT-141 can lead to adverse effects you wouldn’t want to wish upon. 

With the PT-141 review right here, you’ve got the choice to make! 

Is PT-141 FDA approved?

Yes, the FDA has approved the use of PT-141 in women to treat HSDD. Besides that, you can easily purchase the drug for scientific or clinical purposes. 

How to Reconstitute PT-141?

PT-141 injection should be reconstituted with bacteriostatic or sterile water. To do so, drip the water down the side of the vial. Let the solution dissolve. 

Is PT-141 dangerous?

PT-141 has been extensively studied to ensure it doesn’t curtail any life-threatening effects. Thus, it got approved by the FDA. However, that doesn’t make us turn a blind eye to the side effects one might experience with dose accession. 

Is PT-141 a steroid?

No! PT-141 is an anabolic/androgenic steroid. Specifically, it is an analog of alpha-MSH. 

Can PT-141 increase Testosterone levels?

No, PT-141 hasn’t been reported to increase or decrease testosterone levels. 


Kartik Kumar Rathi

Kartik is a Doctor in training currently in his second year of medical school with the ultimate goal of becoming a successful cardiologist, he currently contributes to health blogs, research papers and also founded a social health startup to help educate others.

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