Safest Steroids and Cycles

safest steroids

Steroids. They’ve been around for a very, very long time, and they’ll probably remain for very long still. The truth is Steroids were never invented to be used by athletes or those looking to make some extra gains. No, Steroids were invented to be used in the medical world to help patients gain muscle [1]. One issue with Steroids is that they are not particularly healthy, in fact, that’s why Steroids are being replaced by SARMs. Anyways, let’s look at the Safest Steroids and Cycles for you to use.

Warning: The content on and the information included in this article is intended for entertainment and informational purposes only. It is not intended nor implied to be a substitute for professional medical advice. Prior to buying anything, check that it is compliant where you live with your current government laws. We frequently mention research chemicals that are not made for human consumption. Therefore, before purchasing any product for personal use, consult with your doctor or healthcare provider first.

Key Takeaways

  • All Steroids will have side effects such as raising cholesterol and shutting down Test production
  • You can minimize the risk by using a lower dose and doing shorter cycles
  • There are plenty of products you can use to also reduce the negative impact

What makes Steroids Unsafe?

We all know that Steroid abuse has a bunch of side effects, and while it is certainly possible to lower your risk of injury or illness, caution is advised. The main reason why Steroids are unsafe is because of their very nature.

  • Anabolic Steroids will dramatically increase LDL and Total Cholesterol levels, which over time can lead to cardiovascular disease and heart failure [2]
  • Most Steroids will increase red blood cell production that can, along with increased body weight, massive impact your blood pressure levels [3]
  • Kidney function will be impaired significantly due to Anabolic Steroid use [4]
  • Lastly, athletes use dosages that were never tested by medical professionals. Not only would they experience these side effects, but sometimes in far higher concentration

Can Steroids be Safe?

Completely safe? No. You could make arguments that a lower dose would be safer, and if you make sure you keep an eye on your bloodwork and overall health the risks are fat less sure, however, there will always be a risk.

What are the Safest Steroids?

Firstly, Steroids are inherently not safe. They pose a great deal of health risks and a few other nasty side effects as well. That said, there are a few ‘safer’ Steroids that have specific characteristics that allow them to have fewer or weaker side effects.


Safest Steroids and Cycles
Figure 1: Primobolan Depot (Methenolone) used to be produced for medical use, but is no longer

Primobolan (Primo, Methenolone) is an Anabolic Steroid that has been used extensively in history for medical and sports use. Methenolone enanthate was introduced for medical use in 1962. Since then it has been taken off the market, and so any Primo you find is definitely Underground produced.

Primo is known as one of the least impactful Steroids known to man, and has often been compared to Anavar (Oxandrolone) in terms of side effects. Sure, Primo does have side effects like hair loss, testosterone shutdown, etc, but it’s far less bad than other injectable Steroids.

Many British bodybuilders (and older bodybuilders) will use Primobolan stacked alongside Testosterone to construct a mean cycle. Primo is not really known to cause severe side effects and this is why it is used in higher amounts by bodybuilders and even women.

Steroid FamilyDihydrogentestosterone
Can it Aromatise?No
Worst side effect?Increase in cholesterol
Stacked with?Testosterone, Masteron, Trenbolone, any oral
Safety Rating8/10


Safest Steroids and Cycles
Figure 2: Masteron (Drostanolone Enanthate) is no longer being used in medical environments, even though its characteristics make it a great drug

Masteron (Drostanolone Propionate, Drostanolone Enanthate) is commonly known as the poor man’s Primobolan. Primo is quite hard to synthesize and therefor costs quite a lot. Masteron will give you 80% of the results that Primo would at a far lower price.

Masteron is commonly used in cutting cycles, but can be used in bulking cycles as well. The reality is any Steroid can be used at any time, but certain attributes make it better or worse for some applications. Due to the fact that Masteron can lower estrogen, it is definitely a favorite whilst cutting.

Masteron won’t have a tremendous amount of side effects, but some people have reported hair loss to be prominent whilst on Masteron. That said, you can use Minoxidill to combat this.

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Steroid FamilyDihydrogentestosterone
Can it Aromatise?No (it decreases E2)
Worst side effect?Increase in cholesterol, hair loss
Stacked with?Testosterone, Primobolan, Trenbolone, any oral
Safety Rating7/10


Safest Steroids and Cycles
Figure 3: Anavar (Oxandrolone) is one of the only Steroids still being used in the medical world. Particularly for bone pain associated with osteoporosis, aiding weight gain following surgery or physical trauma, during chronic infection, or in the context of unexplained weight loss, and counteracting the catabolic effect of long-term corticosteroid therapy

Anavar (Oxandrolone, Var) is the first oral-only Steroid on the list. Being an oral, it brings the unique characteristic of being 17-Alpha Alkylated, meaning it is bioactive when taken orally. Unlike other oral Steroids, it shows almost zero hepatotoxicity (liver damage). It does, however, show nephrotoxicity.

This means the biggest side effect of Anavar is kidney damage. Kidneys are incredibly sensitive and unlike the liver, they cannot recover after injury.

Anavar is also a DHT like the other two on this list, and will not convert into Estrogen either. Anavar is typically used alongside other Steroids due to the mild nature of Anavar.

Steroid FamilyDihydrogentestosterone
Can it Aromatise?No
Worst side effect?Nephrotoxicity
Stacked with?Testosterone, Primobolan, Trenbolone
Safety Rating7/10


Safest Steroids and Cycles
Figure 4: Turinabol (Chlorodehydromethyltestosterone) was used in the medical field from 1965 – 1994

Turinabol (Chlorodehydromethyltestosterone, TBol) is one of the mildest Steroids on the market. In fact, it is so mild most people don’t even bother using it at all! That said, it still has the ability to increase muscle size, muscle strength, and aid in recovery.

Gains are lean due to its DHT nature, and the worst side effects are going to be hepatotoxicity and cholesterol issues. Turinabol is another 17-Alpha Alkylated Steroid, thus, it causes harm to the liver.

Turinabol is commonly used by professional athletes who compete in tested federations. Probably due to the short half-life and the fact that it’s easy to hide.

Steroid FamilyDihydrogentestosterone
Can it Aromatise?No
Worst side effect?Hepatotoxicity, cholesterol
Stacked with?Testosterone, Primobolan, Trenbolone
Safety Rating7/10

Honorable Mention: Growth Hormone and Growth Hormone Peptides

Safest Steroids and Cycles
Figure 5: While not a Steroid, Growth Hormone can give users a “similar” result with far fewer side effects

Human Growth Hormone (HGH) is a product that is so common it’s not even used exclusively by athletes and bodybuilders. It is a prescribed medication for those suffering from low levels of Insulin-like Growth Factor 1 or IGF-1.

IGF-1 has been linked to more muscle gain, more fat loss, better hair, better skin, better quality of life, better sleep, and even a better sexual life.

HGH does have side effects, such as decreased insulin sensitivity, water retention, and perhaps carpal tunnel syndrome. That said, compared to the side effects we know of from Steroids this is really nothing.

FactorHuman Growth Hormone
Steroid FamilyIt’s a Peptide
Can it Aromatise?No
Worst side effect?Insulin resistance
Stacked with?Any Steroid, any Peptide, Any SARM
Safety Rating10/10

What are the Most Dangerous Steroids?

“Dangerous” is a relative term, and is used loosely in this application. Each Steroid will have specific sides that will be specifically dangerous to specific people, however, we can create a list that will look at all the Steroids and highlight some of the more shitty ones:

  • Trenbolone is known as one of the most harmful Steroids. It can cause cardiovascular, kidney, brain, and joint damage. Trenbolone was never even meant for human use and was only tested in cattle
  • Deca Durabolin is not terribly dangerous right off the bat, however, it is often used whilst bulking when food and salt is plenty. This can cause blood pressure to spike which can have negative health impacts
  • Equipoise or Boldenone is known as the ‘horse Steroid’ for its ability to dramatically increase hematocrit levels. This will also increase blood pressure, which we know can cause quite a lot of damage
  • Halotestin is not that much more dangerous for the user compared to other Steroids, however, it makes the user quite aggressive – this is Roid Rage in a bottle. It would then make the environment around the user dangerous to others
  • DNP or 2,4-Dinitrophenol is not a Steroid but a fat burner that can literally cause death if used incorrectly

How to make Steroids Safer?

Using Steroids is never 100% safe, and it’s the job of the user to make sure they take all the necessary precautions to reduce the risk. Here are some things you can do to reduce the risk:

Use Less

One phrase that rings true more than ever here is the phrase ‘The poison is in the does”. No one is going to run into cholesterol issues using a wee 150mg of Testosterone per week, but bump that up ten fold and you’re definitely in for a rough time.

Safest Steroids and Cycles
Figure 6: Perhaps as a joke, someone came forth with this ‘death cycle’ and claimed certain bodybuilders actually follow this. If they did, they would die rather quickly – hence the name

If you’re new to using Steroids, it might be a great idea to start with dosages far lower than that of what you would like to use. I’ve had clients come to me running almost a gram and they could barely press 315 on bench…

Use a Coach

There are several coaches online who have had years of experience in the field and they’ve made mistakes you don’t have to! This means a far lower risk of you injuring yourself or wasting your money.

Not too toot my own horn, but I am a coach. I’ve coached more than 300 people (not all bodybuilders), I have a Chemistry degree, and I do bodybuilding myself as well. You can schedule a call with me here.

Do your Bloodwork

It is commonplace to actually do blood tests and see where your blood markers are. Blood cholesterol, pressure, inflammation, blood sugar, estrogen, thyroid function, etc.

This is essential and you should ideally do it 4 times a year, perhaps even more! This is not even a suggestion, but more so a instruction.

Lifestyle Changes

These are some of the more tedious things you need to do but they back ten fold. Things like regular cardio, staying hydrated, eating plenty of fiber, getting in a lot of Omega 3s, etc.


Safest Steroids and Cycles
Figure 7: Certain supplements will be sold as ‘cycle support’

Certain supplements were designed with Anabolic users in mind. Look out for products with, Citrus Bergamot, Kaneka® Ubiquinol, Grape Seed Extract, Celery Seed Extract, Astragalus, N Acetyl Cysteine, IP6, Tudca, and Pine Bark Extract.

Safest Steroids and Cycles

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$35 Lab work 200
For a limited time, you can get a complete hormone panel, along with a consultation with a physician for only $35, thanks to the fine folks at FountainTRT.

FountainTRT can prescribe you the perfect dose of pharmaceutical injectable or topical Testosterone, and their affordable blood work will keep you dialed in the long term for NO extra cost.


Steroids do carry a risk with them which you, as an adult, have to make your peace with. No matter how hard you try you will not be able to get around that.

You can, however, use certain Steroids and Peptides that carry less risk than others to ensure you have a lower risk of running into issues down the road. You can also follow the other tips to ensure you are in the best position while on Cycle.


Safest Steroids for heart

The safest for the heart would have to be Primobolan, Masteron, and (not a Steroid) but the one I would use is Growth Hormone. You can still see tonnes of benefits from Growth.

How many Cycles of Steroids is safe?

They all carry risk.

Is Primobolan the safest Steroid?

Compared to all the other Steroids available, yes.

Still Have Questions?

Drop us a comment down below and one of our expert coaches will respond to it. We’ll also be answering questions on our Instagram!

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Steve Theunissen

Steve Theunissen | Writer

Steve Theunissen is a seasoned fitness professional with 25+ years of experience. He has multiple certifications from the International Sports Sciences Association, including Certified Personal Trainer, Fitness Nutrition Certification, and Strength and Conditioning Certification. He's a knowledgeable and experienced bodybuilding coach, combining his passion for fitness with his writing skills to educate and inspire. Whether starting out or looking to take training to the next level, Steve Theunissen is the ideal coach to help reach fitness goals.

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2 years ago

I’m interested in doing it first time cycle what would be the safest and the length of the cycle with Test. Anavar. Deca and. Dianabol. The amount on the injectables and how much on the Oral. Find about to take a week where is the best website to go bye a full week or six week trial

1 year ago

Nice article even though the main purpose of it is to try to sell some bull shit “legal steroid alternatives” which are 100% a waste of money and will not work. If you want real results, do real gear. All these “steroid alternatives” are s complete waste ⅘

1 year ago

I am a 70year old bodybuilder taking TRT ( Test E ) 150 per week
Could I add anything to this Regards

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