Does MK 677 cause Water Retention? How to Avoid & Resolve it

Water retention and an increase in blood pressure are both dangerous and sore on the eyes. How can we combat water retention from MK-677?

It has been shown that MK 677 can lead to water retention because it secretes Growth Hormone (GH). GH has been clinically proven to cause an increase in water retention, and therefore, MK 677 can also have this side effect. However, the degree of this effect may vary from person to person depending on factors such as lifestyle and genetics.

When it comes to bulking cycles, MK 677 is a popular choice. However, it’s important to consider the amount of water retention it may cause and how to manage it effectively. 

This article provides up-to-date academic data and thoroughly analyzes numerous anecdotal reports and experiences. By reading further, you’ll discover valuable insights on the topic of MK 677 water retention, and we’ll answer the question of how much water retention is Mk 677 responsible for.

Warning: The content on and the information included in this article is intended for entertainment and informational purposes only. It is not intended nor implied to be a substitute for professional medical advice. Prior to buying anything, check that it is compliant where you live with your current government laws. We frequently mention research chemicals that are not made for human consumption. Therefore, before purchasing any product for personal use, consult with your doctor or healthcare provider first.

Key Takeaways

  • Water retention is a common side-effect of ibutamoren
  • Lowering the amount of sodium you consume can be beneficial and help with water weight.
  • MK-677 is an effective supplement that offers numerous advantages. It’s a popular choice for those seeking to improve their bone density, experience better sleep, and prevent muscle loss.

What is MK 677?

If you’re into bodybuilding, you may have heard of Ibutamoren, also known as MK 677. This supplement is a Growth Hormone Secretagogue (GHS) that helps stimulate growth hormone (GH) and insulin production in the body.

After consumption, ibutamoren simulates the functions of ghrelin, a hormone generated in the stomach, to tell the brain that the body is hungry. This happens because the supplement interacts with a specific brain area called the ghrelin receptor (GHSR).

The hormone ghrelin is released to increase our appetite. However, the area of the brain where ghrelin receptors are located is not only responsible for hunger, but it also plays a role in regulating emotions such as temperament and joy.

Cortisol, a hormone in the human body, has the ability to affect the immune system response, slow down the digestive system, and impede healing. Additionally, it could have an impact on learning and memory. Hence, it is recommended to take MK 677, a substance that stimulates cortisol production, in appropriate doses to avoid any adverse effects. (1)

How does MK 677 cause Water Retention?

If you notice water retention while taking ibutamoren, don’t fret, as it’s a common side effect. However, not everyone experiences this. Mostly, it affects those who consume less water or have high sodium intake in their diet.

To reduce water retention, make sure you drink plenty of water and cut down on salt consumption. Additionally, focus on healthy foods during your cycle, and remember, as your body adapts to the supplement, this side effect will resolve on its own.

How to Avoid Water Retention from MK 677?

If you are experiencing excessive water retention and bloating during your bulking phase, there are specific steps you can take to reverse these effects. These steps include making changes to your diet and incorporating supplements. Doing so can improve your overall health and well-being while achieving your desired body composition.

  1. It’s important to increase your water intake. Try drinking more water than you currently do, and aim for at least eight glasses daily to stay hydrated and maintain good health.
  2. Reducing your sodium intake can have a positive impact.
  3. Reducing your carb and junk food intake (2)

If you want to reduce water retention and bloating, try natural diuretics like Dandelion Root or Hawthorn Berry. A daily intake of 500 mg of either supplement should do the trick. By following this protocol, you should see a significant improvement in your symptoms and even better sleep quality.

Other Benefits of MK 677

Ibutamoren MK 677 is a popular supplement that offers numerous benefits. Its users often take it to enhance their bone density, improve their sleep, reduce muscle wasting, and as an anti-aging product.

Increases Muscle Size

MK 677 stimulates the production of Growth Hormone and IGF-1, which work together to promote the growth of bones and tissues. Growth Hormone also aids in increasing muscle mass and strength, particularly in the thighs. However, it’s important to note that MK 677 is not a magic solution, and you must put in the effort by exercising regularly to see the best results. (3)

Strengthens Bones

MK 677 is a supplement that builds muscles and aids in increasing bone mineral density. This is advantageous for seniors, obese individuals, and women experiencing menopause. However, before using ibutamoren, it is essential to research the potential long-term side effects. It’s also worth noting that the supplement needs to be used for over a year for these effects to become apparent.

Anti-Aging Properties

As you get older, the production of the Growth Hormone in your body decreases, which can lead to a loss of muscle mass, one of the signs of aging. However, by taking MK 677, you can boost the production of the Growth Hormone and potentially reduce or eliminate these signs of aging. (4)

Shred Body Fat

It’s a known fact that ibutamoren can help with fat loss. This is because the Growth Hormone affects two enzymes that control the breakdown of triglycerides into fatty acids, ultimately reducing obesity. However, it is important to note that ibutamoren (MK 677) can yield mixed results for different individuals. (5)

Is MK 677 Legal?

It’s important to note that the FDA does not currently approve Ibutamoren. However, certain compounding pharmacies in the US and abroad do offer them by prescription. Some private entities market these drugs as supplements and can also be found on various internet sites specializing in supplementation.

MK 677 can increase the Human Growth Hormone (HGH) levels in the body. However, it is important to note that this substance is considered a poison, has dangerous side effects, and is banned in sports. (6)

Where Can I Buy MK 677?

MK 677 Summary

MK 677

MK 677 is commonly grouped with SARMs when in reality it is not a SARM at all. Regular SARMs will bind to the Androgen Receptors in the muscle tissue (and bone tissue as well) to cause an increase in muscle protein synthesis.

MK 677, however, is a Growth Hormone secretagogue, meaning it will not interact with the Androgen Receptors at all, but only cause an increased release of Human Growth Hormone (HGH) from your own Pituitary gland.

Increased HGH can lead to increased fat loss [2], and muscle gain, and even improve overall life quality.

Because MK 677 does not interact with the endocrine system, it is the “SARM” with the least side effects, making MK 677 a very safe SARM and great for beginners.

Read Our Review of MK677

  • Increased fat loss
  • Improves lean body mass
  • The increased insulin-like growth factor can lead to better hair and skin
  • Abusing the compound can lead to insulin resistance
  • Abusing the compound can lead to edema

MK 677 vs. Other Compounds

MK 677 vs. Human Growth Hormone

If you’re looking for a supplement that can offer anti-aging benefits, help with weight loss and muscle building, and promote overall health, MK 677 is a great option. It’s as effective as HGH supplements and can have similar negative effects. The good news is, though, that MK 677 is easily accessible and doesn’t require a prescription.

MK 677 vs. other SARMs

If you’re looking to build muscle during the bulking phase, there are some strong and effective SARMs you can use. These include Testolone, Ligandrol, Ibutamoren, and Ostarine. Many consider Testolone to be the most effective SARM for bulking out of the four options.

MK 677 vs. Steroids

Unlike other anabolic steroids that can cause severe skin issues like acne, SARM Ibutamoren MK 677 actually promotes healthier skin. One of the key advantages of using this SARM is its ability to enhance the healing process for various skin wounds making it easier and faster to recover.

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Conclusion: What causes Water Retention from MK 677?

Experiencing water retention while taking MK 677 is not a major concern. While it can happen, it’s unlikely if you drink at least 2.5 liters of water daily and maintain a relatively healthy diet. Even if it does occur, it is not a dangerous side effect and typically resolves within a few weeks after you finish your cycle.  

Frequently Asked Questions

How Long Can You Safely Take MK-677?

For optimal results, taking MK 677 in cycles of 16 to 20 weeks with a dosage of 25mg is recommended. Following this cycle, taking a 5-week break before continuing is also suggested. Many users have reported positive results with this cycle. If you are new to taking MK 677, starting with a lower dosage of 15mg per day is advised.

Can MK-677 Cause Bubble Gut?

MK-677 can stimulate appetite, which can lead to increased food intake. When combined with higher levels of IGF-1 and water retention, there is a risk of developing a condition commonly referred to as “bubble gut.” This condition is often seen in bodybuilders who take numerous PEDs.

What Steroid Makes You Retain Water?

Any Steroid that increases estrogen in the body can cause water retention.

Is Bubble Gut Permanent?

Bubble gut is not permanent and can be eliminated by reducing the amount of HGH and insulin in your body or stopping them altogether. It’s also recommended that you avoid artificial substances such as steroids, don’t over-exert yourself, and allow recovery time.

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1. Thau L, Gandhi J, Sharma S. Physiology, Cortisol. [Updated 2022 Aug 29]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from:


3. Svensson J, Ohlsson C, Jansson JO, Murphy G, Wyss D, Krupa D, Cerchio K, Polvino W, Gertz B, Baylink D, Mohan S, Bengtsson BA. Treatment with the oral growth hormone secretagogue MK-677 increases markers of bone formation and bone resorption in obese young males. J Bone Miner Res. 1998 Jul;13(7):1158-66. doi: 10.1359/jbmr.1998.13.7.1158. PMID: 9661080.

4. M. G. Murphy, L. M. Plunkett, B. J. Gertz, W. He, J. Wittreich, W. M. Polvino, D. R. Clemmons, MK-677, an Orally Active Growth Hormone Secretagogue, Reverses Diet-Induced Catabolism, The Journal of Clinical Endocrinology & Metabolism, Volume 83, Issue 2, 1 February 1998, Pages 320–325,

5. J. Svensson, L. Lönn, J.-O. Jansson, G. Murphy, D. Wyss, D. Krupa, K. Cerchio, W. Polvino, B. Gertz, I. Boseaus, L. Sjöström, B.-Å. Bengtsson, Two-Month Treatment of Obese Subjects with the Oral Growth Hormone (GH) Secretagogue MK-677 Increases GH Secretion, Fat-Free Mass, and Energy Expenditure, The Journal of Clinical Endocrinology & Metabolism, Volume 83, Issue 2, 1 February 1998, Pages 362–369,



Brenton Barker

Brenton Barker | Writer

Brenton is a highly qualified sports coach with over 20 years of experience working with professional athletes. With a degree in sports coaching and experience in prominent positions, including Head Advisor to the Japanese Government Sports Institute and Manager & Head Coach to Australia's Governing Sporting Body. Currently, he consults with several professional athletes and sporting organizations, sharing his expertise to help them reach their full potential.

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