Best Peptides for Healing

Injuries are a part of life and a big part of sport. What if there was a way to speed up the healing? Well...
Medically reviewed by Dr. Mohammed Fouda
Dr. Fouda uses his extensive knowledge and expertise as an academic scholar to medically review articles for scientific accuracy and credibility, ensuring that the medical information presented is up-to-date and trustworthy. He is responsible for ensuring the quality of the medical information presented on our website.

Peptides have been all the rave the past few months, grabbing more attention than that one time when that weird lady popped champagne onto her butt. Peptides are without doubt predominantly used for muscle growth and fat loss, I mean that’s the namesake of Growth Hormone.

There are however a few peptides that can help in the healing of joints and injuries, but do they work? Let’s look at the science and find out.

FeaturesBPC-157TB-500CollagenEpithalonARA 290
🩸Best for injuries✅✅✅✅✅✅✅
🏃 Muscle Endurance✅✅✅✅✅
💪💪 Increased Muscle mass✅✅✅✅✅
⚠️ Side effectsDizziness and lightheadednessDizziness and lightheadednessblood clot, high BP, diarrhea🚫blod clot, high BP, diarrhea
💊 Dosage10mg/ml5-20mgFlexibleFlexibleFlexible
☮️ Healing✅✅✅✅✅✅✅✅✅✅✅
👱VendorPure rawzPure rawzBulk supplements.comPure rawzPure rawz
Fights inflammation✅✅✅✅✅✅✅✅
👍 Effects on skin and jointspossiblypossibly✅✅✅possiblypossibly
🤕Best for pain❌❌❌❌✅✅✅
🧠Best for the nervous system❌❌❌❌✅✅✅
Increased protein synthesis✅✅✅✅✅
🔴 angiogenesis✅✅✅❌❌❌❌

Warning: The content on Muscleandbrawn.com and the information included in this article is intended for entertainment and informational purposes only. It is not intended nor implied to be a substitute for professional medical advice. Prior to buying anything, check that it is compliant where you live with your current government laws. We frequently mention research chemicals that are not made for human consumption. Therefore, before purchasing any product for personal use, consult with your doctor or healthcare provider first.

1) BPC 157: Best for Injuries

BPC 157 is a favorite amongst thousands of athletes and bodybuilders because of its ability to trigger angiogenesis, which is the formation of new blood cells. This process can trigger faster healing and a faster generation of cells. Another nifty thing that BPC 157 accomplishes is that it can inhibit or block the effects of 4-hydroxynonenal. 4-hydroxynonenal is a growth-limiting compound, hence its limitation can further accelerate healing.

Studies have found that BPC can help in the healing of joints, ligaments, tendons, and muscles as well. Dosing of around 1-10 mcg per kilogram of body weight seems to be a good place to start, however best to try and find the perfect dose for you. Because of this potentially high dosing, you might want to buy a BPC 157 with a higher concentration.

BPC 157 Summary

BPC-157

BPC-157, or pentadecapeptide, is categorized as a body protection compound. It is composed of 15 amino acids in a very particular sequence that doesn’t exist naturally.

It is artificially synthesized in laboratories using the partial sequence of the body-protecting compounds isolated from gastric juices. Hence, it is one of the derivatives of the peptide found in human gastric juices.

The therapeutic effects of BPC-157 are exerted through multiple courses of action. One of the most common ways that BPC-157 acts as a therapeutic agent is by carrying out angiogenesis, which is the formation of new blood vessels. 

It does this by activating a protein called the “vascular endothelial growth factor” which initiates the formation of new blood vessels. This ensues in the organization of a healthy vascular network which gives BPC-157 its key regenerative and healing properties.

Another mechanism of action of BPC-157 is blocking the inhibitory growth factor called 4-hydroxynonenal, which is a negative modulator of growth. This allows the peptide to carry out effective healing of wounds, especially surrounding tendons.

BPC-157 Overview

⭐️ Top Benefits: Recovery from injury
🧪 Form: Injectable liquid, Nasal Spray
⌛️ Max Time Used: 14 weeks
💰 Average Cost: $51.99
❤️‍🩹 Side Effects: Abdominal pain
☢️ Dangers: Not really
📚 Best Peptide Stack: TB 500 / HGH / IGF-1
➡️ Go to the Full review

  • Improved recovery from injuries
  • Improved gastric function
  • Injection site pain
  • Abdominal pain

2) TB 500: Best Against Inflammation

TB 500 is another great peptide used for healing. TB 500 (or Thymosin Beta 4) is found naturally in humans and animals, and veterinarians initially found a use for it in horses before doctors applied it to humans. TB 500 increases actin, which can increase cell mobilization, and cell division, and even fight inflammation.

TB 500 can have quite a large dose, ranging from 5 – 20 mg per week, it might be better to buy a higher concentration vial like this one from Pure Rawz which will comfortably cover all your recovery needs.

TB500 Summary

TB-500

Thymosin beta-4 is a small peptide with G actin-sequestering action. It is associated with the induction of angiogenesis and accelerated wound healing (10).

TB-500 is a synthetic version of the naturally occurring peptide LKKTETQ. The peptide segment (17)LKKTETQ(23) is the active site within the protein thymosin β(4) responsible for actin binding, cell migration and wound healing

Muscle fibers are made up of actin and myosin, which are contractile filaments. These filaments allow our muscles to contract and relax for mobility and carry out efficient metabolism and cell signaling.

TB-500 increases our body’s response to actin by increased reception of the protein by the peptide segment (17)LKKTETQ(23). This upregulation promotes increased cell growth, healthy cell proliferation, healing effects, and cell migration, particularly keratinocytes and endothelial cells.

TB-500 promotes angiogenesis which is the formation of new blood vessels. It builds up new blood vessel pathways for efficient blood supply to the wounds for increased healing. It also augments beneficial inflammation at the site of injuries.

TB-500 Overview

⭐️ Top Benefit: Rapid recovery from injuries
🧪 Form: Injectable liquid, Capsules, Transdermal patches
💉 Typical Dosage: 7.66 mg/week
⌛️ Typical cycle duration: 14 weeks
💰 Average Cost: $69.99
✅ Availability: Easily available
❤️‍🩹 Side Effects and Dangers: Headaches and stomach discomfort
📚 Best Peptide Stack: BPC-157 / TB-500
➡️ Go to the Full review

  • Rapid wound healing
  • Heals ligament and joint injuries
  • Helps build endurance
  • Injection site pain
  • Abdominal pain
  • Headaches

3) Collagen: Best for Skin and Joints

Best Peptides for Healing

Collagen is one of the most popular peptides on the market for healing. Collagen is the most abundant protein in your body, thus supplementing with it has been shown to increase joint, skin, and tendon recovery and lowering pain in those areas as well.

Usually, Collagen is derived from mammalian sources which of course limits its use in people who do not include these animals in their diet, like pescatarians. Rest easy, the good people at Bulk Supplements not only stock this Bovine Collagen but others as well, like fish-derived Collagen. Hah! Pescatarians rejoice!

4) Epithalon: Best New Peptide

A relatively new peptide on the market, Epitalon has been found to activate the body’s regeneration properties, which can of course accelerate healing.

Furthermore, Epitalon induces the release of Telomerase. When Telomerase is activated within a cell, the cell will continue to grow and divide – greatly accelerating healing.

Epitalon Summary

Epitalon

Epitalon, also commonly known as Epithalon peptide or Epithalone is a synthetic tetrapeptide with four amino acids in its structure.

This synthetic peptide was originally discovered by Russian scientist Vladimir Khavinson. Since then most of the clinical studies centered around Epitalon were carried out at the St. Petersburg Institute of Bioregulation and Gerontology.

Epitalon is a synthetic telomerase activator enzyme that upregulates the synthesis of telomerase enzyme by the pineal gland. Thus, telomeres at the end of chromosomes are renewed and more telomeres are available at the tips of DNA strands even after a cell divides repeatedly.

Besides, Epitalon treatment also stimulates melatonin production as well as regulates its secretion. This helps restore normal circadian rhythm as melatonin secretion is a critical chemical that balances the sleep/wake cycle.

Some human clinical studies also suggest that this synthetic pineal peptide Epitalon also modulates the blood levels of gonadotropins.

Epithalon Overview

⭐️ Top Benefits: Anti-aging and better sleep
🧪 Form: Injectable liquid
⌛️ Max Time Used: 2 – 3 Weeks
💰 Average Cost: $86.99
❤️‍🩹 Side Effects: Nausea and stomach discomfort
☢️ Dangers: Not really
📚 Best Peptide Stack: HGH / IGF-1
⚤ Men/Women: Men and women
➡️ Go to the Full review

  • Anti-aging
  • Better sleep
  • Nausea
  • Stomach discomfort

5) ARA 290: Best for Pain and Nervous System

Best Peptides for Healing

A common injury we see often is those that are known as neuropathic, meaning an injury regarding your nervous system. Also a very new peptide amongst lifters, some studies suggest this product gets into the central nervous system extremely quickly, extremely fast, and lowers inflammation at the pain point (at a particular nerve) rapidly.

ARA counteracts tissue damage through its effect on inflammation and its actions on IRR (insulin receptor-related receptor) by mimicking the effect of erythropoietin (3). Pure Rawz stocks ARA 90, and as far as nerve injuries go this is one of the best products you can use for the job.

Side Effects

Collagen has very few side effects. Heartburn, maybe feeling very full after consuming it. So not too bad really. The others however can be a bit different. BPC 157 can cause dizziness and headaches. TB 500 causes similar effects, dizziness and lightheadedness.

Epitalon has no reported side effects, and ARA 90 has several bad sides like blood clots, high blood pressure, and diarrhea… Lovely.

What are Peptides?

Peptides are short chains of amino acids that are naturally present in foods, around 2 – 50 amino acids. Scientists have discovered that if we change the sequence of the amino acids they can have certain effects on the human body. The two most common ones are collagen and creatine, both peptides that can have significant effects when administered.

Best Peptides for Healing

It’s important to know that peptides differ from proteins, as peptides are a much shorter chain and some need to be taken subcutaneously. Fun fact, injecting your whey protein can have catastrophic side effects, so don’t do that, please. Jokes aside, peptide treatments have been used by doctors since the 1920s and are still used today, but more popular for their use in sports and recreational lifting.

How do Peptides work?

The first thing you need to know before we open this pickle jar is that there are hundreds of peptides. Some, like CJC 1295 can result in massive muscle gain, and something like Melanotan gives you a better tan. The most popular peptide type used is going to be those that result in muscle gain. Using a GHRH (growth hormone-releasing hormone) causes the release of growth hormone, which can cause muscle gain and fat loss. Combining a GHRH with a GHRP (growth hormone-releasing peptide) can amplify this and increase the secretion of growth hormone.

This article is going to be about healing, so let’s focus on how peptides can heal you. Healing peptides such as BPC 157 work by increasing the production of certain enzymes, proteins, or just new tissue to aid in recovery. Of course, a peptide like Melatonin will help because you’ll sleep more, however, the big boys will help you a whole lot more than just getting a few more Z’s.

Benefits of Healing Peptides

Individual peptides will have certain benefits, however, there are some correlations between them when looking from a generalized perspective:

  • Increased
    • muscular recovery
    • joint recovery
    • cellular regeneration
    • angiogenesis
    • skin quality
  • Decreased
    • inflammation
  • Improved sleep

Something like Collagen is 100% legal to buy over the counter or online. Stores like Bulk Supplements sell powdered Collagen that can be a great and legal addition to your supplement stack.

Other peptides, the injectable ones, are a bit trickier. While you may find them on online sites, they can only be sold as experimental products, and not for human use.

Who should use Healing Peptides?

Healing peptides can be administered by doctors for various injuries, ranging from ligament to muscular. Peptides are often used by bodybuilders, athletes, and recreational lifters to speed up the healing process of an injury. If a certain peptide has a certain side effect that can be very detrimental to your health, maybe not use that particular one.

Can BPC 157 heal old injuries?

Possibly. Injuries remain the same years down the line, just with less inflammation and you learn to cope with it. The danger of being injured again still looms. BPC 157 creates new blood vessels regardless of where they are, so yes BPC 157 could heal an old injury.

Are peptides good for ligament healing?

The ones mentioned in this article are yes.

Is Growth Hormone a good healing peptide?

Potentially, but at what cost? No really, real GH is super hard to find and even harder to afford. It can potentially help in healing, but there is a reason researchers invented and use other peptides for healing… Because they’re more suited for the job at hand.

Does IGF 1 heal ligaments?

Surprisingly, yeah. Just don’t get scared when you suddenly start looking like The Rock midway through your cycle. Baby oil is not included.

Conclusion

Healing peptides are one of the better-growing niches in the fitness world and can get you out of a pickle when needed. I would go for the injectables because I’ve used collagen myself, the effects were good but not magical. Make sure you do your rehab, take it slow, and you’ll be tearing it up in the gym in no time. You are badass.

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Drop us a comment down below and one of our expert coaches will respond to it. We’ll also be answering questions on our Instagram!

Contributors

Daniel Louwrens BSc PT

Daniel Louwrens BSc PT | Writer

Daniel Louwrens is a well-rounded fitness professional with over 10 years of experience in bodybuilding and fitness. He holds a BSc in Chemistry from the University of Western Cape and is a certified International Personal Trainer and Nutritionist. He is also a skilled bodybuilder and head coach for Muscle and Brawn. With his knowledge and expertise, he provides personalized training, nutrition, and recovery guidance to help clients reach their fitness goals.

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Dr. Mohammed Fouda

Dr. Mohammed Fouda | Reviewer

Dr. Fouda uses his extensive knowledge and expertise as an academic scholar to medically review articles for scientific accuracy and credibility, ensuring that the medical information presented is up-to-date and trustworthy. He is responsible for ensuring the quality of the medical information presented on our website.

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Cooper
1 year ago

Looking to heal a achilles tendonopthy injury ive had for 2 years with sarm or peptides along with PT. Any suggestions and sites to get it from

Bob
4 months ago

High
I was told that I need total shoulder replacement do too my arthritis and bad cartilage.
I work out four days a week ride a bike 10 to 15 a week when I can down here in South Carolina. Are there any peptides that heal my cartilage.

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