Testosterone Sustanon 250: Side Effects and Typical Gains

Class of Compound


Mechanism of Action

Sustanon 250 is a blend of four different testosterone esters, two are slow acting while two are fast acting. It exerts its anabolic effect by binding with Androgen Receptors (ARs) and stimulating protein synthesis in muscle cells.

Street Names

Sustanon 250, Omnadren 250


  • Increases protein synthesis in muscles
  • Stimulates muscle repair
  • Increases vascularity

Side Effects and Dangers

  • Low testosterone production
  • Water retention
  • Prostate enlargement

Chemical Structure

Testosterone (sustanon 250) is one of the most-used steroids among bodybuilders, mainly because it’s an exceptional compound for building muscle. However, there’s various other benefits to adding test to your cycle.

One reason why many gym rats use testosterone is because it doesn’t pose many health risks compared to other anabolics.

Also when it comes to transforming your body, sustanon 250 has anabolic AND fat-burning properties; making it perfect for bulking or cutting.

So, if you’re trying to pack on 20lbs of muscle or want to lose some puppy fat that you’ve gained over Christmas; sustanon 250 can help you.

Other benefits to Sustanon 250:

  • It’ll help you get jacked (when bulking)
  • Burns more fat when cutting
  • Builds/retains muscle when on low calories
  • Increases strength and endurance

You get the picture…

There’s not much sustanon 250 can’t do.

What is Testosterone Sustanon 250?

Testosterone sustanon is the most popular type of testosterone which is a blend of 4 different testosterone’s:

  • Propionate (30mg)
  • Phenylpropionate (60mg)
  • Isocaproate (60mg)
  • Decanoate (100mg).

Testosterone sustanon is fast-acting AND stays in the user’s system for long periods of time.

This is due to it containing both long and short esters – in a 60-40% ratio.

Isocaproate and Decanoate are long esters that are slow acting. And Propionate and phenylpropionate are the short esters (fast-acting).

Combining long and short esters in one compound means testosterone will remain in your blood stream for longer periods, without you needing to inject the steroid all the time (which is required with short ester steroids).

This magical combination of esters is why sustanon 250 is regarded the most powerful form of testosterone; giving users slightly superior muscle gains compared to other forms of test.

Side Effects

If a person is using sustanon 250, because they have low testosterone, known as TRT (testosterone replacement therapy); they aren’t likely to experience side effects because they’re only increasing their test to a normal range.

In this scenario they are using testosterone to improve their health.

Side effects start to occur when bodybuilders use sustanon 250 to sky rocket test levels so he/she can experience dramatic muscle growth.

The side effects of sustanon 250 are similar to dianabol, with them having a similar chemical structure. However, sustanon 250 will have more androgen-based side effects due to its higher androgenicity.

So, with test you’re more prone to: oily skin, acne, hair loss, gyno, water retention and prostate enlargement (due to higher levels of DHT).

A user will also experience some water retention and higher blood pressure as a result of cycling testosterone sustanon. This is due to harmful cholesterol levels going up (LDL), and good cholesterol levels (HDL) going down.

Note: CrazyBulk’s legal steroid Testo-Max does not come with these side effects. Testo-Max mimics the effects of Sustanon 250, without the harsh side effects.

Typical Gains

Sustanon 250 can be used during a bulk or a cut. It’s extremely anabolic, due to it dramatically increasing protein synthesis, nitrogen retention and IGF-1 (insulin-like growth factor) levels in the body. Thus you’ll see remarkable increases in strength and size.

For those that don’t know, IGF-1 is a hormone similar to GH (growth hormone). So, IGF-1 is anabolic, promoting new lean muscle tissue; but is less effective at burning fat than GH.

It’s normal to gain 15lbs of muscle in 4-5 weeks when on sustanon 250. This is applicable to newbies only, experienced steroid-users will gain less.

Whilst on testosterone, your muscles will look hard and full; without significant amounts of water retention.

If you combine sustanon 250 with other bulking compounds such as anadrol or dianabol, then muscle and strength gains will be enhanced even more. Such a stack could produce 30+ lbs of weight gain from a 4-6 week cycle.

Testosterone also has fat burning effects, making it an effective cutting steroid too.

For those who’re anxious about losing muscle/strength during a cut, testosterone will become your new best friend; as it suppresses glucocorticoid, reducing catabolic (muscle-wasting) hormones such as cortisol.

Sustanon 250 will preserve your hard-earned muscle tissue, and assuming your cut is slow and non-aggressive, you should also add some muscle whilst cutting.

Alternatively if you do decide to use testosterone during a bulk, you’ll accumulate less fat when eating in a calorie surplus due to its fat burning effects.

Sustanon 250 also increases your red blood cell count, increasing muscular endurance. This’ll especially help when regularly doing cardio or performing workouts on lower calories where your energy levels would usually be low.

Sustanon 250 is also considered as one of the best steroids for beginners, as it’s not an overly toxic compound.

Other testosterone esters, such as cypionate, enanthate and propionate will produce similar results to sustanon 250. However, each of these different testosterone esters will kick in at different times.

For example, testosterone propionate is a fast-acting steroid, thus results can come fast. However, testosterone cypionate is a slow acting compound, and thus takes longer to produce gains (with users often needing a longer cycle to feel the full effects).

Sustanon 250 has a mixture of short and fast esters, therefore it still kicks in relatively fast. 


Although Sustanon 250 isn’t an overly toxic steroid, it does require injections, therefore users need to be very careful. A misplaced injection could lead to someone being paralyzed or even worse (death).

Therefore, it’s important users are knowledgeable about how to administer this steroid.

Also sustanon 250 will shut down testosterone levels post-cycle, therefore a PCT is required to help recover natural testosterone production as fast as possible. Without a PCT, endogenous testosterone production may take up to 4 months to recover (in most cases).

If sustanon 250 or any other anabolic steroids become abused, testosterone levels can become impaired long-term.

Anyone with an existing heart condition, or high blood pressure is recommended to stay away from sustanon 250 and other steroids, as this compound will only deteriorate the heart further. 

Testo-Max from Crazy Bulk is a much safer alternative, with it being 100% legal to buy, and approved by the FDA. Therefore, you won’t run the risk of getting caught doing illegal activities via the black market, and you won’t need to worry about your health rapidly declining on-cycle.

Testo-max also comes in pill form, thus there’s no need for injections (which can be painful). Despite Testo-Max being an oral, it is not hepatotoxic, therefore it will not strain your liver. Thus, liver support such as milk thistle or TUDCA are unnecessary to take during your Testo-Max cycle.

Ernst Peibst

Ernst Peibst has spent over 3,000 hours researching anabolic steroids and PED's. He's also dedicated the last 7 years educating people about their effects, with hundreds of thousands of people reading his articles. He's studied countless science papers, read several expert books and has consulted some of the finest doctors in the world - on the topic of steroids.

2 Responses

  1. Yeah I’m taking sustanon 250. I was wondering if there’s anything you can do for the oily skin and the swelling in the feet and ankles its not harmful is it

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