ACP-105 Review: Benefits, Uses, Dosage

ACP-105, one of the potent SARMs is a partial agonist and offers a lot in terms of increasing lean muscle mass, cutting down body fat, enhancing cognition by altering the hippocampal regions, and whatnot! Read more to find out whether you should start using this SARM or not
Medically reviewed by Dr. Mohammed Fouda
Dr. Fouda uses his extensive knowledge and expertise as an academic scholar to medically review articles for scientific accuracy and credibility, ensuring that the medical information presented is up-to-date and trustworthy. He is responsible for ensuring the quality of the medical information presented on our website.
ACP-105_review-01

With the idea of big and bulky muscles making noise nowadays, everyone particularly the upcoming generation is more inclined towards gaining muscle mass

While gym membership is one of the first steps, augmenting their gym hustle with peptides and SARMs can make them achieve results quickly

But it is not always easy to find out the right peptide and SARMs which can make your journey haphazard rather than fruitful. 

Of course, every compound you plan to use has a fair share of side effects to offer, thus it is important to make the right choice. 

To make your picks easier, we’re going to discuss one of the most potent SARMS (ACP-105) and today, we’re going to do a detailed ACP-105 Review!

The latter is gaining popularity as each day passes and seems to be a pretty decent option for bodybuilding aspirants. 

Key Takeaways

  • ACP-105 is a potent Selective Androgen Receptor Modulator (SARM) with enhanced affinity for skeletal muscles, initially developed for degenerative disorders but increasingly used in sports and fitness.
  • ACP-105 selectively binds to androgen receptors, reducing high-density lipoproteins, increasing lean muscle mass, and avoiding estrogen level spikes.
  • ACP-105 provides various benefits, including enhanced cognitive function, muscle growth without wasting, quicker recovery from injuries, sustained energy, and reduced water retention.
  • ACP-105 aids in muscle building by binding to skeletal muscle and increasing both mass and endurance. The recommended dosage is 1 mg/kg per day for 8-13 weeks.
  • User reviews indicate positive outcomes with minimal side effects. Stacking ACP-105 with other SARMs is suggested for cutting and bulking, but caution is advised due to potential side effects.

Warning: The content on Muscleandbrawn.com and the information included in this article is intended for entertainment and informational purposes only. It is not intended nor implied to be a substitute for professional medical advice. Prior to buying anything, check that it is compliant where you live with your current government laws. We frequently mention research chemicals that are not made for human consumption. Therefore, before purchasing any product for personal use, consult with your doctor or healthcare provider first.

ACP-105 Review: What is ACP-105?

ACP-105, biochemically known as 2-Chloro-4-[(1R,5R)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octan-8-yl]-3-methyl benzonitrile, is a potent Selective Androgen Receptor Modulators, commonly known as SARMs (1). 

SARMs are compounds with anabolic properties similar to those of androgenic steroids, however, with much less detrimental effects. One such SARM product that created waves was ACP-105

ACP-105, through clinical trials, proved to have an enhanced affinity for skeletal muscles. Acadia Pharmaceuticals initially manufactured ACP-105 to assist patients with certain degenerative disorders

However, with increasing research and development, owing to its potential role in muscle building, it has increasingly been used in sports and fitness

How Does ACP-105 Work?

ACP-105, like many other SARMs, works by selectively binding to androgen receptors. With this preferable binding, ACP-105 doesn’t cause unnecessary effects on other vital organs of our body (2). 

Besides this, ACP-105 helps reduce the levels of high-density lipoproteins alongside increasing lean muscle mass.

Additionally, due to a lack of aromaticity, the compound does not induce an increase in estrogen levels, thereby decreasing water retention.  

ACP-105 indeed has increased potency and stronger anabolic effects; however, it still does not surpass the potential benefits of testosterone. Nonetheless, this makes ACP-105 much safer to use. 

ACP-105 is a partial agonist and does not cause much of a suppression one would expect with other SARMs. 

However, that doesn’t mean you wouldn’t need Post Cycle Therapy (PCT). One needs to have PCT with them at all times since testosterone suppression by ACP-105 can result in fatigue and exhaustion.  

Due to a lack of further research and scientific knowledge, the working mechanism of ACP-105 is still unclear and is a point of objection.  

ACP-105 Review: Benefits of ACP-105

Benefits of ACP-105 🌟
Increases Non-Fat Mass πŸ‹οΈβ€β™‚οΈ
Reduces Abnormal Fat πŸš«πŸ”
Enhances Cognitive Function 🧠
Promotes Muscle Mass Growth πŸ’ͺ
Treats Degenerative Bone Disorders 🦴
Boosts Energy and Stamina ⚑
Accelerates Injury Recovery 🩹
Minimizes Water Retention πŸ’¦

Even though it might be a topic of concern for some since ACP-105 is a partial agonist, unlike other SARMs, it might not be as potent as it sounds. However, let me burst your bubble. 

Despite being a partial agonist, ACP-105 undoubtedly results in various benefits, all directed towards making our body stronger with negligible side effects

It works to decrease high-density lipoprotein found inside the body, thus ACP-105 helps increase non-fat mass in your body and helps you get rid of abnormal fat. 

Research suggests that ACP-105 helps enhance cognitive function by increasing androgen receptors in the hippocampal region (3). 

ACP-105 also aids in the growth of muscle mass without causing any muscle wasting. This feature of ACP-105 is useful in treating degenerative bone disorders such as osteoporosis.

With ACP-105 supplementation, you can stay energetic and active for longer periods without experiencing fatigue or tiredness (4). 

More importantly, ACP-105 is a much safer option when SARMs are concerned as compared to other androgenic anabolic steroids. 

During injury, ACP-105 can provide quicker recovery by decreasing the healing time. 

Lastly, non-aromatization helps reduce water retention and possible bloating

With the abovementioned enlisted benefits, one can infer that ACP-105 indeed provides a greater range of pros to its supplementation despite having limited research and knowledge. 

ACP-105 Review: Usage in Bodybuilding

ACP-105, when employed in bodybuilding, operates akin to other Selective Androgen Receptor Modulators (SARMs). 

It functions by selectively attaching to androgen receptors found in skeletal muscles, fostering the augmentation of both muscle mass and endurance

This characteristic proves advantageous in facilitating the bodybuilding journey. Recommended dosages, based on studied protocols, suggest a daily intake of 1 mg/kg for a duration spanning 8 to 13 weeks

The compound’s mechanism involves a targeted interaction with androgen receptors, avoiding unnecessary effects on vital organs. 

This specificity not only enhances muscle development but also contributes to the overall efficiency and safety of the bodybuilding process.

In adherence to the prescribed dosage and recommended cycle duration, individuals can anticipate the positive impact of ACP-105 on muscle growth and stamina. 

It is noteworthy that, despite its similarities with other SARMs, ACP-105’s distinctive features and favorable anabolic effects position it as a noteworthy supplement in the realm of bodybuilding

As with any performance-enhancing substance, prudent use, adherence to recommended guidelines, and awareness of potential side effects remain crucial for individuals incorporating ACP-105 into their fitness regimen.

ACP-105 Dosage

For optimal use of ACP-105, adhering to the recommended dosage is essential. Clinical trials, primarily conducted on rats, propose a suggested daily intake of 1mg/kg

To provide a practical perspective, an average man weighing around 79 kg would necessitate a daily dose of 79 mg.

Timing plays a crucial role in maximizing the benefits of ACP-105 supplementation. It is advised to administer the supplement approximately thirty minutes before embarking on a morning workout session. 

This strategic timing aligns with the compound’s mechanism, enhancing its potential impact on skeletal muscles during the exercise routine. 

Additionally, coupling the ACP-105 intake with a post-meal administration further optimizes its absorption and utilization within the body.

By meticulously following these dosage recommendations and incorporating strategic timing into the regimen, individuals can potentially harness the desired effects of ACP-105, promoting its efficacy in supporting muscle development and endurance. 

As with any supplementation routine, understanding and adhering to the specified dosage guidelines contribute significantly to the safe and effective integration of ACP-105 into one’s fitness routine.

Cycling – ACP-105 Review

In the context of ACP-105 usage, adhering to a recommended cycling duration is pivotal for optimal results. 

Typically, a cycle spanning 8 to 13 weeks is advised for individuals incorporating ACP-105 into their fitness regimen. 

This timeframe is strategically determined to balance the potential benefits of the compound with the need for periodic breaks to mitigate any potential side effects or tolerance buildup.

It’s noteworthy that women, in particular, are advised to follow a modified dosage and cycle duration. For females, the recommended daily dose is reduced to 5mg, and the cycle duration is shortened to 6 to 8 weeks. 

This tailored approach takes into account the physiological differences between genders and aims to optimize the positive effects of ACP-105 while minimizing any associated risks.

Side Effects of ACP-105

The saying, no gain without pain surprisingly holds in the case of ACP-106 supplementation as well. Despite being very potent, the partial agonist can still expose you to certain unpleasant side effects

Initial supplementation with ACP-105 could be accompanied by mild headaches that usually resolve quickly if the recommended ACP-105 dosage is considered.

With increasing doses, headaches can get more serious and require medical attention. 

Besides that, after seven to eight weeks of starting ACP-106, your body may start to experience fatigue and exhaustion.

This is a sign of testosterone suppression with prolonged use of ACP-105. To remedy the situation, one is directed to use PCT to aid your body in refreshing. 

User Reviews of ACP-105

One of the best ways to figure out whether the product you’re planning to use is authentic or carries any potential side effects that could prove adverse to your health is to look for the user experience

Likewise, for ACP-105, we extracted some of the legit customer experiences that could assist you in making a better decision. 

One of the users mentions that, 

β€œZero sides, strength gains were better than I expected considering I was in a significant caloric deficit. No water retention at all. It’s probably the best Cutter I’ve used if side effects are your main concern.”

Another one writes a comparison between ACP-105 and Ostarine, 

β€œIn my experience, ACP was more suppressive than Osta, but on the other hand, ACP had little impact on lipids and liver enzymes. Osta was much harsher on lipids and liver for me, go figure.”

Another one mentions that 

β€œACP105 over Ost all day. The only negative is it is more suppressive.” 

With these reviews, one can figure out that ACP-105 is indeed one of the most effective SARMs however it can get a bit more suppressive compared to others. 

ACP-105 Stacks 

Even though ACP-105 alone can do wonders for our bodies, stacking it up with other SARMs can undoubtedly prove to be a cherry on top. 

For Cutting stacks, the following are recommended: 

ACP-105 (10mg/day) + Ostarine (25mg/day) + Cardarine (10mg/day)

If you are looking for the best cutting stack, go nowhere else! 

Because all these SARMs can plausibly follow a quite similar mechanism of action, using this stack means one can reduce all the unnecessary fat in their body, alongside increasing lean muscle mass, making you look smarter physically. 

For Bulking stacks, the following are recommended: 

ACP-105 (10mg/day) + Ligandrol (20mg/day) + YK-11 (10 mg/day): 

If you want quick results with increasing muscle mass and bulking it, using this stack will help you. 

With this stack, one can increase a considerable muscle mass alongside adjusting it to a high-caloric diet.  

The legal status of ACP-105 and other Selective Androgen Receptor Modulators (SARMs) remains uncertain as they have not received approval from the Food and Drug Administration (FDA)

This lack of official endorsement is primarily attributed to an ongoing quest for a comprehensive understanding of their precise mechanisms of action and potential implications on the body, precluding a definitive confirmation of safety. 

The absence of FDA approval has led to heightened scrutiny and criticism surrounding the use of these substances as supplements.

While the regulatory status is in limbo, user reviews, at present, have not highlighted any severe adverse effects linked directly to ACP-105

Despite this, exercising caution is paramount, and the selection of a reputable vendor for SARMs becomes imperative. 

The absence of official validation necessitates a discerning approach in sourcing these supplements, emphasizing the importance of thorough research and due diligence when considering their incorporation into fitness or wellness routines. 

As the regulatory landscape evolves, individuals must stay informed and prioritize safety when navigating the legal and ethical dimensions of SARM usage.

Insider Secrets: How to Use SARMs and Peptides to Uncover Ripped Muscles

Unlock your potential with our SARMs and Peptides Secrets Ebooks πŸ”₯ πŸ§ͺ πŸ’Š πŸ’ͺ πŸ’‰ 🩸πŸ₯ πŸ₯Ž πŸ€

Where to Buy ACP-105?

This can be a hassle for you because not many online vendors sell ACP-105 because of multiple reasons. One of which is legality issues and the other is the fact that ACP-105 is not well-researched at the moment. 

Nonetheless, I tried finding the best vendors selling the SARM and Pure Rawz is again on top!  

Best Place To Buy ACP-105

Best Place To Buy ACP-105: Pure Rawz

Elevate your peptide experience with Pure Rawz, an industry leader that stands out as the ultimate destination for acquiring ACP-105 and more. Renowned as the Best Place to Buy ACP-105, Pure Rawz distinguishes itself with a steadfast commitment to unparalleled quality and innovation within the peptide realm.

Similar to the dedication seen in Biotech Peptides, Pure Rawz places a premium on rigorous testing and exceptional product standards. A beacon of excellence, the brand seamlessly combines quality with affordability, ensuring customers have access to top-tier peptides without compromise.

Pure Rawz’s extensive inventory boasts a variety of injectable peptides and topical variants, tailored to meet diverse needs and preferences.

Noteworthy are their unique blends, designed for cutting-edge combinations that align with various health and fitness goals, showcasing Pure Rawz’s commitment to continuous innovation.

As a trailblazer in the industry, Pure Rawz doesn’t rest on its laurels. The company consistently introduces new peptides, ensuring customers stay at the forefront of advancements in the field.

With a meticulous testing process anchoring their operations, Pure Rawz guarantees the delivery of premium and reliable products, solidifying its position as the go-to choice for individuals seeking quality-tested peptides that push the boundaries of excellence.

Brand Overview

πŸ’Š πŸ§ͺ Forms: Liquid and Powder SARMs, Peptides, and Nootropics
πŸ“„ Lab Verified (COA): Yes, ensuring the highest quality and purity standards.
πŸ“¬ Shipping Policy: 5 days a week, if order above $94, no shipping charges.
πŸ’΅ Payment Methods: Cryptocurrency/Google Pay
βœ… Guarantees: Hassle-free exchange policy for damaged products.
πŸ“¦ Other Products: Powder SARMs, Peptides, and Nootropics.
🏷 Price (MK-677 35ml equivalent): $65.48
🏷 Price (RAD-140 35ml equivalent): $64.98
⭐️ Rating: Impressive 4.75-star rating
➑️ Go to the Full review

  • Extensive range of peptides and almost everything else
  • Worldwide shipping
  • Regular sales and discount codes
  • Certificates of authenticity not available
  • Does not accept credit cards

ACP-105 Review vs Other Compounds

ACP-105 vs. OstarineACP-105 vs. RAD140ACP-105 vs. S4 (Andarine)
Cheaper and Affordable πŸ’°Rapid Muscle Gain πŸ’ͺEfficient Fat Loss πŸš΄β€β™‚οΈπŸ”₯
Longer Shelf-life πŸ“…Minimal Side Effects 🚫😷Considerable Side Effects ⚠️❌
Enhanced Availability 🌐Muscle Pump Effect πŸ’¦πŸ”₯Contraindicated in Sports πŸš«πŸ†

ACP-105 vs. Ostarine

Ostarine, like ACP-105, is a SARM initially introduced in the market to prevent muscle wasting and treat degenerative bone disorders such as osteoporosis. 

However, ostarine is better compared to ACP-105 in multiple ways, such as: 

  • It is cheaper and more affordable 
  • Has a longer shelf-life 
  • Enhanced availability 
  • Has more clinical studies and research on it 

ACP-105 vs RAD140

RAD-140, like ACP-105, is probably the most potent anabolic compound available in the market that boosts our muscle mass to the standard.

It helps increase muscle mass gain, strength, and losing unwanted fat, all in 6 to 8 weeks of supplementation. 

RAD-140 also has minimal side effects when compared with anabolic steroids. 

Interestingly, RAD-140 acts as a pump by making muscles retain more water, making the muscles look bulkier and healthier. 

ACP-105 vs. S4

S4, commonly known as Andarine, is one of the most potent SARMs used by bodybuilders during the cutting phase.

The SARM helps reduce fat loss more efficiently, thus letting your body get rid of additional fat. 

However, the side effects of S4 supplementation are quite a lot, according to certain resources; thus, it is contraindicated in sports. 

Is ACP-105 Legit? 

In conclusion, the discourse surrounding ACP-105 underscores its potential as a potent and legitimate Selective Androgen Receptor Modulator (SARM), despite the limited scope of research and clinical trials. 

The relative benefits attributed to ACP-105 supplementation, coupled with its purported minimal side effects, position it as an appealing option for individuals seeking enhanced muscle development and fat loss.

Acknowledging the scarcity of comprehensive research on ACP-105, there is an element of caution in recommending its use. 

However, the positive user experiences and reported benefits suggest that, for those aiming to shed unhealthy fat and concurrently bolster muscle mass, ACP-105 could be a viable consideration.

Is ACP 105 a SARM?

Yes, ACP-105 is a Selective Androgen Receptor Modulator (SARM). However, unlike other SARMs, ACP-105 is a partial agonist rather than a complete one. 

Can ACP 105 be used in diabetic patients? 

Some users have stated that supplementing with ACP-105 has improved their sugar levels. However, there isn’t much scientific evidence suggesting that. Therefore, getting in touch with your physician before making any choice is important. 

Which SARM is the best for muscle growth? 

We wish we had a clear-cut answer to this question. However, thorough evidence has narrowed the results to fewer products, including RAD-140, ACP-105, and MK2866. Some even state that ACP-105 is indeed the best and unbeatable SARM. 

Can I stack ACP-105 with Ostarine? 

Yes! You can indeed stack up ACP-105 with Ostarine. ACP-105 can be stacked up with any other SARM with minimum side effects. 

Do I need a PCT with ACP-105? 

Yes! You will need Post Cycle Therapy (PCT) while supplementing with ACP-105. ACP-105 can suppress testosterone levels after 6 to 8 weeks of the cycle leading to fatigue and nausea. To combat this, your body will need PCT to refresh

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1) https://pubchem.ncbi.nlm.nih.gov/compound/11638442
2) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867967/
3) https://pubmed.ncbi.nlm.nih.gov/24020966/
4) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3867967/

Contributors

Kumar Rathi

Kumar Rathi | Writer

Kartik is a medical student with a passion for anatomy and physiology. He writes research papers, articles and blogs to raise awareness and also has a strong interest in teaching and public speaking. Aspiring to be a successful cardiologist, Kartik believes in connecting with people on a personal level and is an expert in peptides.

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Dr. Mohammed Fouda

Dr. Mohammed Fouda | Reviewer

Dr. Fouda uses his extensive knowledge and expertise as an academic scholar to medically review articles for scientific accuracy and credibility, ensuring that the medical information presented is up-to-date and trustworthy. He is responsible for ensuring the quality of the medical information presented on our website.

Read all articles
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Doug Lockwood
Doug Lockwood
11 months ago

You said the dosage should be 1mg/kg of bodyweight per day. So, how does that equate to 11mg for a 79kg man?? A 79kg man would require 79mg per day. Please explain the contradiction.

Daniel Louwrens BSc PT
Admin
11 months ago
Reply to  Doug Lockwood

Simple grammatical error, thank you for pointing it out

Chemical Structure

Mechanism of Action

Acp-105 selectively binds to androgen receptors, thereby increasing lean muscle mass and reducing high-density lipoproteins. It is a partial agonist, and therefore, its suppression is minimal, unlike other SARMs. Acp-105 also increases estrogen levels which decreases water retention.

Class of Compound

SARMs

Street Names

Benzonitrile, Acp-105

Effects

Builds muscle, enhances fat loss, improves your cognitive function, increases strength, treats degenerative bone disorders

Side Effects and Dangers

Headache, Fatigue, exhaustion, Not FDA approved

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