ACP-105 SARM: Benefits, Uses, Dosage

ACP-105, one of the potent SARMs is a partial agonist and offers a lot in terms of increasing lean muscle mass, cutting down body fat, enhancing cognition by altering the hippocampal regions, and whatnot! Read more to find out whether you should start using this SARM or not
Medically reviewed by Dr. Mohammed Fouda
Dr. Fouda uses his extensive knowledge and expertise as an academic scholar to medically review articles for scientific accuracy and credibility, ensuring that the medical information presented is up-to-date and trustworthy. He is responsible for ensuring the quality of the medical information presented on our website.

With the idea of big and bulky muscles making noise nowadays, everyone particularly the upcoming generation is more inclined toward gaining muscle mass. 

While gym membership is one of the first steps, augmenting their gym hustle with peptides and SARMs can make them achieve results quicker. 

But it is not always easy to find out the right peptide and SARMs which can make your journey haphazard rather than fruitful. 

Of course, every compound you plan to use has a fair share of side effects to offer, thus it is important to make the right choice. 

To make your picks easier, we are talking today about one of the potent SARMs ACP-105.

The latter is gaining popularity as each day passes and seems to be a pretty decent option for bodybuilding aspirants. 

Warning: The content on and the information included in this article is intended for entertainment and informational purposes only. It is not intended nor implied to be a substitute for professional medical advice. Prior to buying anything, check that it is compliant where you live with your current government laws. We frequently mention research chemicals that are not made for human consumption. Therefore, before purchasing any product for personal use, consult with your doctor or healthcare provider first.

What is ACP-105?

ACP-105, biochemically known as 2-Chloro-4-[(1R,5R)-3-hydroxy-3-methyl-8-azabicyclo[3.2.1]octan-8-yl]-3-methyl benzonitrile, is a potent Selective Androgen Receptor Modulators, commonly known as SARMs (1). 

SARMs are compounds with anabolic properties similar to those of androgenic steroids, however, with much less detrimental effects. One such SARM product that created waves was ACP-105. 

ACP-105, through clinical trials, proved to have an enhanced affinity for skeletal muscles. Acadia Pharmaceuticals initially manufactured ACP-105 to assist patients with certain degenerative disorders. 

However, with increasing research and development, owing to its potential role in muscle building, it has increasingly been used in sports and fitness. 

How Does ACP-105 Work?

ACP-105, like many other SARMs, works by selectively binding to androgen receptors. With this preferable binding, ACP-105 doesn’t cause unnecessary effects on other vital organs of our body (2). 

Besides this, ACP-105 helps reduce the levels of high-density lipoproteins alongside increasing lean muscle mass. Additionally, due to a lack of aromaticity, the compound does not induce an increase in estrogen levels, thereby decreasing water retention.  

ACP-105 indeed has increased potency and stronger anabolic effects; however, it still does not surpass the potential benefits of testosterone. Nonetheless, this makes ACP-105 much safer to use. 

ACP-105 is a partial agonist and does not cause much of a suppression one would expect with other SARMs. 

However, that doesn’t mean you wouldn’t need Post Cycle Therapy (PCT). One needs to have PCT with them at all times since testosterone suppression by ACP-105 can result in fatigue and exhaustion.  

Due to a lack of further research and scientific knowledge, the working mechanism of ACP-105 is still unclear and is a point of objection.  

Benefits of ACP-105

Even though it might be a topic of concern for some since ACP-105 is a partial agonist, unlike other SARMs, it might not be as potent as it sounds. However, let me burst your bubble. 

Despite being a partial agonist, ACP-105 undoubtedly results in various benefits, all directed towards making our body stronger with negligible side effects. 

It works to decrease high-density lipoprotein found inside the body, thus ACP-105 helps increase non-fat mass in your body and helps you get rid of abnormal fat. 

Research suggests that ACP-105 helps enhance cognitive function by increasing androgen receptors in the hippocampal region (3). 

ACP-105 also aids in the growth of muscle mass without causing any muscle wasting. This feature of ACP-105 is useful in treating degenerative bone disorders such as osteoporosis.

With ACP-105 supplementation, you can stay energetic and active for longer periods without experiencing fatigue or tiredness (4). 

More importantly, ACP-105 is a much safer option when SARMs are concerned as compared to other androgenic anabolic steroids. 

During injury, ACP-105 can provide quicker recovery by decreasing the healing time. 

Lastly, non-aromatization helps reduce water retention and possible bloating. 

With the abovementioned enlisted benefits, one can infer that ACP-105 indeed provides a greater range of pros to its supplementation despite having limited research and knowledge. 

ACP-105 Usage in Bodybuilding

ACP-105 works similarly to most SARMs. The compound binds to the androgen receptors present on the skeletal muscles and increases both muscle mass and endurance, aiding you in the bodybuilding process. As far as the studied dose is concerned, it is advised to use 1 mg/kg per day for 8 to 13 weeks. 

Unlike other supplements, SARMs or ACP-105 have not yet been approved by the Food and Drugs Administration (FDA). Since we are still not completely near to finding out the exact mechanism of action and how it might affect our body without creating any obvious symptoms, these products are highly criticized. 

Nevertheless, the user reviews haven’t reported any severe side effects yet. Thus, it would be best to find the right vendor for your SARMs


The recommended dosage of ACP-105, as suggested by clinical trials that were predominantly tested on rats, suggests 1mg/kg per day. That being said, an average man weighing approximately 79 kg will require 11 mg daily. 

It is important to supplement with ACP-105 approximately half an hour before a workout in the morning and after a meal. 


A Cycle of 8-13 weeks with ACP-105 is normally advised. 

For women, however, the dosage is reduced to 5mg daily, with a 6-8 weeks cycle duration. 

Side Effects of ACP-105

The saying, no gain without pain surprisingly holds in the case of ACP-106 supplementation as well. Despite being very potent, the partial agonist can still expose you to certain unpleasant side effects. 

Initial supplementation with ACP-105 could be accompanied by mild headaches that usually resolve quickly if the recommended ACP-105 dosage is considered. With increasing doses, headaches can get more serious and require medical attention. 

Besides that, after seven to eight weeks of starting ACP-106, your body may start to experience fatigue and exhaustion. This is a sign of testosterone suppression with prolonged use of ACP-105. To remedy the situation, one is directed to use PCT to aid your body in refreshing. 

User Experiences 

One of the best ways to figure out whether the product you’re planning to use is authentic or carries any potential side effects that could prove adverse to your health is to look for the user experience. 

Likewise, for ACP-105, we extracted some of the legit customer experiences that could assist you in making a better decision. 

One of the users mentions that, 

“Zero sides, strength gains were better than I expected considering I was in a significant caloric deficit. No water retention at all. It’s probably the best Cutter I’ve used if side effects are your main concern.”

Another one writes a comparison between ACP-105 and Ostarine, 

“In my experience, ACP was more suppressive than Osta, but on the other hand, ACP had little impact on lipids and liver enzymes. Osta was much harsher on lipids and liver for me, go figure.”

Another one mentions that 

“ACP105 over Ost all day. The only negative is it is more suppressive.” 

With these reviews, one can figure out that ACP-105 is indeed one of the most effective SARMs however it can get a bit more suppressive compared to others. 

ACP-105 Stacks 

Even though ACP-105 alone can do wonders for our bodies, stacking it up with other SARMs can undoubtedly prove to be a cherry on top. 

For Cutting stacks, the following are recommended: 

ACP-105 (10mg/day) + Ostarine (25mg/day) + Cardarine (10mg/day)

If you are looking for the best cutting stack, go nowhere else! 

Because all these SARMs can plausibly follow a quite similar mechanism of action, using this stack means one can reduce all the unnecessary fat in their body, alongside increasing lean muscle mass, making you look smarter physically. 

For Bulking stacks, the following are recommended: 

ACP-105 (10mg/day) + Ligandrol (20mg/day) + YK-11 (10 mg/day): 

If you want quick results with increasing muscle mass and bulking it, using this stack will help you. 

With this stack, one can increase a considerable muscle mass alongside adjusting it to a high-caloric diet.  

Where to Buy ACP-105?

This can be a hassle for you because not many online vendors sell ACP-105 because of multiple reasons. One of which is legality issues and the other is the fact that ACP-105 is not well-researched at the moment. 

Nonetheless, I tried finding the best vendors selling the SARM and Pure Rawz is again on top!  


Pure Rawz is one of the best vendors to look for when buying peptides or SARMs. ACP-105 is one of the popular sarm to be sold out by the brand. 

It comes with 33mg per ml for 30ml, totaling 1000mg.

Although the price of $139.98 might sound a bit expensive to some, the product is true of the highest quality, as proven by its customer review. With its secure checkout, third-party testing, and free delivery of over $100, pure rawz indeed knows how to gain user trust.

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ACP-105 vs Other Compounds

ACP-105 vs. Ostarine

Ostarine, like ACP-105, is a SARM initially introduced in the market to prevent muscle wasting and treat degenerative bone disorders such as osteoporosis. 

However, ostarine is better compared to ACP-105 in multiple ways, such as: 

  • It is cheaper and more affordable 
  • Has a longer shelf-life 
  • Enhanced availability 
  • Has more clinical studies and research on it 

ACP-105 vs RAD140

RAD-140, like ACP-105, is probably the most potent anabolic compound available in the market that boosts our muscle mass to the standard. It helps increase muscle mass gain, strength, and losing unwanted fat, all in 6 to 8 weeks of supplementation. 

RAD-140 also has minimal side effects when compared with anabolic steroids. 

Interestingly, RAD-140 acts as a pump by making muscles retain more water, making the muscles look bulkier and healthier. 

ACP-105 vs. S4

S4, commonly known as Andarine, is one of the most potent SARMs used by bodybuilders during the cutting phase. The SARM helps reduce fat loss more efficiently, thus letting your body get rid of additional fat. 

However, the side effects of S4 supplementation are quite a lot, according to certain resources; thus, it is contraindicated in sports. 

Is ACP-105 Legit? 

With everything discussed related to ACP-105, one can infer the relative benefits that come with the supplementation of ACP-105. It is indeed one of the most potent and legitimate SARMs accompanied by the least possible side effects.

While I agree that not much research and clinical trials have been performed involving the ACP-105, I would still maybe recommend trying out ACP-105 if you’re looking to lose unhealthy, abnormal fat alongside increasing muscle mass. 

Is ACP 105 a SARM?

Yes, ACP-105 is a Selective Androgen Receptor Modulator (SARM). However, unlike other SARMs, ACP-105 is a partial agonist rather than a complete one. 

Can ACP 105 be used in diabetic patients? 

Some users have stated that supplementing with ACP-105 has improved their sugar levels. However, there isn’t much scientific evidence suggesting that. Therefore, getting in touch with your physician before making any choice is important. 

Which SARM is the best for muscle growth? 

We wish we had a clear-cut answer to this question. However, thorough evidence has narrowed the results to fewer products, including RAD-140, ACP-105, and MK2866. Some even state that ACP-105 is indeed the best and unbeatable SARM. 

Can I stack ACP-105 with Ostarine? 

Yes! You can indeed stack up ACP-105 with Ostarine. ACP-105 can be stacked up with any other SARM with minimum side effects. 

Do I need a PCT with ACP-105? 

Yes! You will need Post Cycle Therapy (PCT) while supplementing with ACP-105. ACP-105 can suppress testosterone levels after 6 to 8 weeks of the cycle leading to fatigue and nausea. To combat this, your body will need PCT to refresh

Still Have Questions?

Drop us a comment down below and one of our expert coaches will respond to it. We’ll also be answering questions on our Instagram!


Kumar Rathi

Kumar Rathi | Writer

Kartik is a medical student with a passion for anatomy and physiology. He writes research papers, articles and blogs to raise awareness and also has a strong interest in teaching and public speaking. Aspiring to be a successful cardiologist, Kartik believes in connecting with people on a personal level and is an expert in peptides.

Read all articles
Dr. Mohammed Fouda

Dr. Mohammed Fouda | Reviewer

Dr. Fouda uses his extensive knowledge and expertise as an academic scholar to medically review articles for scientific accuracy and credibility, ensuring that the medical information presented is up-to-date and trustworthy. He is responsible for ensuring the quality of the medical information presented on our website.

Read all articles
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Chemical Structure

Mechanism of Action

Acp-105 selectively binds to androgen receptors, thereby increasing lean muscle mass and reducing high-density lipoproteins. It is a partial agonist, and therefore, its suppression is minimal, unlike other SARMs. Acp-105 also increases estrogen levels which decreases water retention.

Class of Compound


Street Names

Benzonitrile, Acp-105


Builds muscle, enhances fat loss, improves your cognitive function, increases strength, treats degenerative bone disorders

Side Effects and Dangers

Headache, Fatigue, exhaustion, Not FDA approved

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