Noopept Review and Stacks (Updated 2022)

When you’re a child, learning comes easily. Your brain is still developing, and it’s easier to rewire it based on behavior and cognitive patterns. As you grow out of early childhood, it can feel as though it’s harder to learn new things. You may have trouble concentrating, you might feel sluggish toward the end of the day and perhaps you’re not as productive as you wish you could be.

Wouldn’t it be nice if there were a pill that could instantly boost your brainpower? You’re in luck.

Warning: The content on and the information included in this article is intended for entertainment and informational purposes only. It is not intended nor implied to be a substitute for professional medical advice. Prior to buying anything, check that it is compliant where you live with your current government laws.

What is Noopept?

Noopept is a cognitive enhancer that improves your brain function. Noopept is made of N-phenylacetyl-L-prolylglycine ethyl ester, a synthetic dipeptide that produces nootropic effects. Nootropic comes from the Greek words that mean “affecting the mind.” Nootropics are a class of medications and supplements that help boost mental functions, including memory. They are considered to be safe, nontoxic and not habit-forming.

Although everybody is different, in most people, the brain continues to develop throughout the mid-20s. As your brain develops, the synapses are continually “pruned” to create the most efficient pathways for operation.

The more a particular pathway is used, the more myelin is created to surround the nerve fibers along that pathway, making communication via that pathway faster. That’s why certain actions and mental patterns seem easier the more you do them. Connections within the brain are strengthened during the process of brain development too.

If you’re at an age during which your brain is still developing, you can optimize the growth by putting yourself in an environment that provides plenty of enrichment and challenges, getting enough exercise and sleep, managing stress and eating a healthy diet. Supplementation with certain substances can help strengthen brain development.

Does that mean that your brain can’t change after you turn 30? No. Your brain is constantly changing and adapting. This is called neuroplasticity. Neuroplasticity is thought to create the physical foundation of brain functions like learning and memory.

Noopept has been found to accelerate the release of brain-derived neurotrophic factor (BDNF). This protein is the most dominant growth factor in the central nervous system. It is vital for encouraging the flexibility of the neurons. If you can encourage your synapses to continue creating and selectively cropping connections as you age, you can enhance your brainpower throughout your life.

Is Noopept Legal?

Noopept is 100% legal in the U.S. You can lawfully purchase, possess and use it. That means that you won’t get in trouble for buying it, even if you purchase it over the internet or from another country.

Noopept is not regulated by the Food and Drug Administration (FDA). That means that it hasn’t been explicitly approved for treating specific ailments or conditions. That doesn’t mean that it is any less effective than drugs that have been approved by the FDA, however.

In fact, makers of dietary supplements don’t have to seek FDA approval. For example, herbal supplements can be just as potent as synthetic medications, but the manufacturers just don’t have to undergo the same approval process as manufacturers of some other drugs.

Because Noopept isn’t subject to FDA approval, it may be difficult to locate in your local health food store. However, you can buy Noopept online.

If you live outside of the U.S., verify whether Noopept is legal in your country. It is also currently legal to buy it for personal use without a prescription in the UK, Canada and Australia.

Noopept Benefits & Side Effects

Noopept has been studied for its effects on memory, cognition and neuroplasticity. Many users say that the compound helps them excel at what they’re already doing. Think about it: if you can focus on exactly what you’re doing and improve your memory and learning capacity while you’re doing it, you’ll improve your performance.

Spacial Memory

Noopept has been found to improve special memory in rats. Spacial memory involves the ability to record information about yourself in relation to your environment. This can help you navigate your way through your town or remember where you put your keys when you’re trying to leave the house.

Brain Protection

Noopept is a neuroprotective dipeptide. Its neuroprotective effects can help prevent or treat damage to brain cells. Oxidative stress can damage the central nervous system, including the brain. It can lead to anxiety, depression and emotional stress. Oxidative stress caused by other factors, such as alcohol abuse, can worsen neuroinflammatory disorders.

Noopept has anti-inflammatory properties that may be able to reverse some of this damage to the brain. The drug’s antioxidant properties also aid in the removal of toxins from neurons, helping to protect them and maximize their health.

Short-Term Cognitive Function

Noopept can improve learning and memory. It can help you to pick up and remember new information, which is especially advantageous for students. It can also improve concentration. If you are required to focus for long periods of time during your daily life, Noopept can help improve your attention span.

Long-Term Cognitive Function

Although not enough studies have been conducted to determine exactly what Noopept’s effects are in the long-term, most research points to its benefits for protecting cognitive function as you age.

Some neurological disorders, such as Alzheimer’s and Parkinson’s, are associated with aging. There is evidence that shows that certain sticky proteins in the brain can get in the way of neuronal function. Research shows that Noopept can prevent the cognitive decline caused by these sticky proteins. It can even restore memory that has been lost due to these plaques in the brain. It also has benefits for people suffering from Parkinson’s disease.

Brain Growth and Development

Every time you go through a particular experience, neurons fire and synapses are connected in the brain. These pathways make the experience more familiar next time you go through it. Every time you have a new experience, your brain has to figure out how to adapt by creating new pathways. If you limit your experiences, the synapses that were required to process them are eventually disconnected.

As you grow out of the brain development stage, it takes more stimulation to wire and re-wire your brain than it did when you were a child. Because Noopept can enhance the creation o
f nerve growth factor (NGF) and BDNF, it can help new neurons and synapses develop throughout your life. This will improve your long-term memory, skills development and learning. In short, it helps make your brain more adaptive and versatile.

Increase Alpha Brain Waves

As the neurons in your brain fire, electricity helps them communicate with each other. This communication is the foundation of all of our thoughts, feelings and actions. All of this electrical activity creates brain waves, which are divided into five bandwidths.

Scientists have found that increasing alpha brain waves can help us relax, improve our moods and become more creative. While meditating and mindfulness can increase alpha waves, so can Noopept. It also increases beta brainwaves in the hippocampus and right cortex. This can boost your analytical skills, focus and logic.

Cholinosensitizing Effects

Choline is one of the main neurochemicals responsible for memory construction and reasoning. Some nootropics actually deplete choline in the brain by helping the brain to use it more rapidly. This results in the need to supplement with choline.

Noopept makes the brain more receptive to choline by heightening the sensitivity of the cholinergic receptors. This allows the neurons in the brain to utilize choline more effectively without using it up.

Other Benefits of Noopept

Users and researchers also report the following benefits and effects of Noopept:

  • Better categorization and storage of information for long-term memory
  • Increased alertness
  • Improvements in information processing
  • Better communication ability
  • Improvements in mood
  • Enhanced problem solving
  • Improved creativity
  • Heightened reflexes

Noopept and Alcohol

We mentioned that the antioxidant benefits of Noopept can reverse brain damage caused by alcohol abuse. Alcohol is one of the leading causes of cognitive impairment.

Although some of the damage caused by alcohol, such as slurred speech and problems with balance, improves once you sober up, other brain deficits may endure even after you stop drinking. Heavy drinking can cause memory lapses, mental confusion and learning problems.

Because Noopept encourages neurogenesis, the formation of new brain cells, it can combat the negative effects of alcohol on brain cells. However, there is no concrete advice or research available to suggest whether Noopept is safe to take with alcohol.

If you’re thinking of taking Noopept with alcohol, some users report that it may not be the best idea. One user said that the combination increased lack of judgment. Others said that it made them feel more drunk.

Taking Noopept with alcohol can reduce the symptoms of a hangover the next day, however. Instead of feeling sluggish, many users wake up feeling alert and refreshed after taking Noopept with alcohol.

The bottom line is that the effects of combining Noopept and alcohol are unpredictable. Your dose, the way your body metabolizes alcohol and other medications that you might be taking can all affect the results.

Side Effects: Is Noopept Safe?

No toxic or allergenic reactions have been found after administration of Noopept. However, that doesn’t mean that individuals won’t experience side effects while taking the drug.

One study found that some side effects associated with Noopept were:

  • Trouble sleeping
  • Irritability
  • Increased blood pressure

In this study, a total of 53 patients received either Noopept or Piracetam, a less potent form of Noopept. Out of 31 participants that took Noopept, only two experienced side effects that could be linked with the drug. Irritability was one of the side effects that could not be reliably correlated with consumption of Noopept.

If you take more than the recommended dose, you may experience gastrointestinal issues or excess irritability. Some users also report feeling foggy and less clear-headed when they take too much Noopept.

We suggest that users begin with the recommended dose and adjust it based on their own response. We cannot recommend safely mega-dosing with Noopept. We would suggest that you consult with a medical professional before beginning to use Noopept, especially if you already take other medications.


Racetam nootropics, like Piracetam, Aniracetam, Pramiracetam and Oxiracetam, have often been associated with headaches. Users who take these types of drugs may have headaches every once in a while or every time they take the compounds.

These headaches are linked with the drugs’ interaction with choline in the brain. Acetylcholine is a neurotransmitter that helps the brain build connections. It is largely responsible for cognitive flexibility.

Choline in the body helps to create the acetylcholine neurotransmitter. Choline has been linked to long-term memory and learning abilities. However, many people are deficient in this essential nutrient.

Piracetam has been found to facilitate cholinergic transmission. This may be one reason for its nootropic benefits. However, this can also cause a deficiency of acetylcholine. Especially if you are already deficient, you may get a headache. No studies have been conducted to determine if this is the exact reason for people taking racetams to experience headaches, but it’s a valid theory.

Noopept has not been found to cause headaches in users. In fact, some users claim that noopept can alleviate headache pain. This is possibly due to the fact that Noopept works by modulating the transmission of glutamates, not acetylcholine, in the brain.


Because of its psychostimulatory effects, Noopept may make it hard for you to sleep, especially if you take it close to bedtime or combine it with other stimulants, like amphetamines or caffeine. Some people stack Noopept with other supplements, such as Phosphatidylserine, to promote relaxation and sleepiness at the end of the day.

Many users report having vivid dreams and a better ability to recall them upon waking. This may not occur with all users. Some people say that Noopept makes them have more difficulty remembering their dreams. One user claimed that the drug may have caused sleep paralysis, although this appears as though it may have been an isolated incident.

If you already have trouble sleeping, take Noopept toward the beginning of the day. You may be able to experiment with the dosage in order to tak
e advantage of the drug’s effects on lucid dreaming toward the end of the day, however.


People who feel anxious throughout the day may have a hard time regulating these feelings. Many stimulants can increase their heart rate and temperature, making them feel more anxious. Some people with anxiety may even turn to dangerous recreational drugs in order to moderate the anxiety.

Anxiety has been associated with a GABA deficiency in the brain. GABA is a neurotransmitter that’s created from glutamate. Low GABA makes your neurons fire more rapidly, which can produce feelings of anxiety. Noopept increase the uptake of glutamate, which can lead to a GABA increase. Therefore, taking Noopept can help you feel less anxious.

Instead of providing the euphoric effects associated with some recreational drugs, Noopept may deliver a calming effect that helps to soothe anxiety. Users report feeling more confident while taking the drug. This can help relieve the stress associated with social anxiety.

Although Noopept has been associated with anxiolytic effects, we don’t recommend taking it primarily for anxiety. If you suffer from anxiety, you may get the best results by seeking assistance from a doctor.


Many users have reported feeling more positive while taking Noopept. Depression may be caused by a number of chemical and environmental factors. It is unclear whether Noopept works directly on the chemicals responsible for depression in the brain. However, the way it works on the GABA receptors, as described above, may increase the drug’s potential to alleviate symptoms of depression.

In addition, research has found that NGF may play a part in psychiatric diseases such as depression. The ability of Noopept to increase NGF may be responsible for its mood-boosting capabilities.

In one study, Noopept eliminated behavior associated with learned helplessness in rats. This may be significant when you look at it from the point of view of human depression. Learned helplessness may be responsible for feelings of negativity or hopelessness. It may also result in behaviors associated with depression. People who are stuck in a cycle of negativity and inaction may be able to break out of it by using Noopept.

As we recommended for people who are experiencing anxiety, we suggest that people dealing with depression seek professional care before taking nootropics.


Some people claim that Noopept helps alleviate withdrawal symptoms when they stop taking other medications and drugs such as alcohol or benzodiazepine. A high density of benzodiazepine receptors in the hippocampus is partly responsible for feelings of anxiety. Some people become addicted to benzodiazepine because it hits these receptors and makes them feel better. Noopept inhibits the function of these receptors.

Noopept also has been found to lower the activity of stress-induced protein kinases, enzymes that are responsible for moving potentially damaging stimuli through cellular pathways. When taken with certain anticonvulsant drugs, Noopept has also been found to diminish the risk of seizure.

These findings make it a promising compound to take when undergoing withdrawal from some other substances, including alcohol and benzodiazepine.

What about withdrawal symptoms stemming from Noopept itself? Researchers have not reported any withdrawal symptoms in people who stop taking Noopept. However, users have experienced decreased mental clarity, negative moods, anxiety and diminished libido upon discontinuing the supplement. These withdrawal symptoms are generally mild and should go away once the body has adapted to the lack of Noopept in the system.


The neurotransmitter acetylcholine has been correlated with the ability for a man to get an erection. Many nootropics cause an increase in the uptake of acetylcholine, which could cause a boost in libido followed by a crash if choline is not supplemented.

Because Noopept doesn’t increase the uptake of choline, it may not have this effect on libido. Its sensitization of the choline receptors may actually point to its ability to improve the libido.

However, a little research into user reviews demonstrates that many people report a lowered libido while taking Noopept. Others report having a sustained libido but having difficulty achieving orgasm. Still other users say that because Noopept heightens their sensitivity, their libido is somewhat increased simply because they seek out stimulating sexual experiences.

Scientists have not assessed the link between libido and Noopept, so there are no studies that demonstrate the supplement’s effect on sex drive. The best way to find out if it affects libido is to keep track of your sexual urges while you’re taking the supplement and adjusting the dose as necessary.

Noopept Review & User Experiences

Everyone who takes Noopept has a slightly different experience. User experiences can be affected by fatigue, other medications, diet, exercise and perception. Those who are more aware of their bodies and emotions may report stronger effects than people who are not in tune with themselves. If you take Noopept and don’t notice a difference in your cognitive function, you might want to slow down and become more mindful of your physical and mental state in general.

It can help to record factors like your mood, sleep habits, dietary habits, libido and daily activities before you start taking any nootropic to establish a baseline. As you start taking the supplement, continue to record these items. This can be the best way to notice the changes that are happening by taking Noopept.

4 Ingredients That Fight Brain Fog

These 4 ingredients discovered by Russian scientists were shown to improve brain function, memory formation, and recall in numerous clinical studies.

Many people who begin using Noopept powder describe feeling a great deal of mental clarity. They are usually able to focus their minds on whatever they’re working on and concentrate without diverting their attention.

You may feel as though it’s easier to form a cohesive thought. This makes tasks that involve thought, intellect, reasoning and perception seem easier. If you don’t have to work as hard to come up with a solution to a question, you might even feel more intelligent. Noopept doesn’t directly enhance intelligence, but it does improve the capacity for learning, categorizing and remembering.

Some people don’t notice a change in ease of thought, but they experience heightened sensations. They may be more aware and alert. This can help them observe the environment around them and take in and remember external stimuli. People who are extremely sensitive to Noopept may notice their ability to remember details that they never noticed previously. If you expose yourself to a variety of stimuli while taking Noopept, you will benefit from its ability to help the
brain create new connections and improve learning.

When you’re having a conversation, you may be able to speak more colorfully and clearly. You may find that you come up with words more easily. Some users report having better writing and verbal skills. This is all due to the mental fluidity that Noopept can impart on users.

Does Noopept make you feel smarter? That depends on the person. Many users report feeling more confident socially and mentally. This confidence can make you feel more intelligent, although your IQ isn’t necessarily affected. However, you might sound smarter when you have to give a presentation at work or feel like it’s easier to write a paper or excel at an exam.

If you don’t notice a difference in your mental abilities, try finding a reputable brain game to test your cognition. Most brain training software offers an assessment that allows you to determine your baseline. Continue to use the brain training software or game regularly while taking Noopept. Assess your cognitive abilities within a few weeks and see if there has been a change.

Some people say that Noopept changed their lives for the better. Others find that they can’t distinguish between the effects of the nootropic and the regular shifts in cognition that they have. Noopept isn’t going to turn you into a superhuman with out-of-this-world cognitive abilities. One study showed that repeated administration improved learning in animals that didn’t respond after the first dose.

In addition, there are users who report feeling worse after taking Noopept. Although not as common, some people say that racing thoughts make it harder to concentrate. Others report feeling less creative while taking Noopept, although they can still focus more intently. Some people say that it exacerbates feelings of anxiety and depression.

If you want to try a nootropic for its brain-enhancing effects, you should have realistic expectations. You may also want to consider lifestyle and behavioral changes along with taking the supplement. For example, if you eat junk food and soda all day, you may have brain fog and difficulty concentrating simply because you’re not fueling your body and brain properly. If you’re not in good mental and physical health before taking a nootropic, the nootropic may not bring about the positive results that you expected.

Long-Term Use

Studies that we have referred to in this article point to the fact that long-term use of Noopept can enhance your cognitive abilities and even prevent cognitive decline from age or trauma. However, no studies have been conducted to specifically determine the safety of long-term Noopept use.

Noopept can alter your brain structure and chemistry. Some researchers believe that different parts of your brain can change in size with the use of nootropics. No one has studied what happens to the brain structure and chemistry when you discontinue long-term use, however.

Because the supplement is more potent than many other nootropics, you don’t have to introduce a large amount of the chemical into your system to notice effects. That makes many reviewers feel as though Noopept is safe for long-term use without any toxicity buildup.

What Dosages To Use

There has not been a sufficient amount of research conducted to determine the ideal dose for Noopept in humans. Most people suggest using a dosage of 10 to 30 mg. This is the recommended dosage listed by That website also recommends taking it for up to 56 days at a time before cycling off of the supplement.

Many other sources recommend cycling the supplement. That means that you should stop taking it for a certain amount of time before you continue to use it again. A number of internet sources have provided the instructions that are included in a bottle of 10 mg capsules. Those instructions state that you can use the drug for 1.5 to 3 months at a time, discontinuing its use for one month before resuming.

The instructions also advise that if you take 30 mg per day, the doses should be spread out. It should be taken with food.

What Is the Half-Life?

According to the Noopept insert, the half-life of the supplement is about 20 minutes. That doesn’t mean that the drug will lose effect within that time frame, however.

The half-life of a drug indicates the length of time that it takes half of the drug to be eliminated from the body. A drug’s effects don’t necessarily disappear once the drug is no longer in the bloodstream. Because Noopept acts upon neurotransmitter receptors in the brain and allows for the release of additional substances related to brain development, its effects last longer than 20 minutes.

Can You Overdose?

According to the package insert, there is no research indicating the amount of Noopept that would result in overdose. Anecdotal evidence suggests that many people have ingested up to 1 g of the substance with few major side effects.

According to one report, the LD50, or median lethal dose, is 5,000 mg per kg. That means that someone who weighs 80 kg would have to take about 400 grams in order to die from overdose.

Taking A Megadose

Some people do take larger-than-recommended doses to amplify the effects. If you stop feeling the effects over time or hit a plateau, one source recommends increasing the dosage to 120 mg per day.

Typical megadosing involves taking 100 to 500 mg of Noopept per day. Many online forums contain accounts from users who have taken megadoses of the supplement.

Results include:

  • A major productivity boost
  • Extreme ability to focus
  • Ability to see colors and details more vividly
  • Enhanced hearing abilities
  • Improved mental capacity overall
  • Enhanced creativity
  • Increased energy and motivation

Some people who have taken a megadose report experiencing unwanted physical side effects, such as stomach upset and dizziness. Several users have found that they begin to forget things that they normally remember. This effect can last for several weeks after they have stopped megadosing. Others say that they feel emotionally numb or experience a lingering headache after megadosing.

Can You Build A Tolerance?

Some users claim that you can build a tolerance to Noopept. It may depend on the individual’s perceptions. One user stated that daily dosing increases the intensity of Noopept’s effects. However, this source claimed that the effectiveness plateaued after 10 days.

The author of Mental Health Daily believes that if you feel the need to increase your dose because you are no longer feeling the effects of a drug, you have developed a tolerance to it. Whether this tolerance is physiological or perceived, it can feel very real.

Even if you are not physically addicted to a substance, you may become dependent on it. With dependence comes the potential to develop a tolerance.

Best Way To Take Noopept

Noopept is available in powder, pill or capsule form. You can mix the powder with a liquid and drink it, put it into an empty capsu
le and swallow it or place it under your tongue for sublingual absorption. It may be more effective when taken sublingually. If you have been taking Noopept orally without seeing results, try administering it sublingually.

Most people take Noopept in the morning, with additional doses administered in the early afternoon if necessary.

Taking Noopept Sublingually

The powdered form of Noopept can be administered by placing it underneath the tongue. This allows it to be absorbed into your bloodstream with minimal interference from digestive enzymes.

To take Noopept sublingually, place the desired amount of powder beneath your tongue. Allow it to sit for a minute or two. After a couple of minutes, rinse your mouth with a flavored juice or mouthwash to eliminate the bitter flavor. Depending on the dose, you may need to allow the product to sit under your tongue for a longer period of time.

Some sources say that sublingual administration can make you feel overly sensitive to the supplement, because it reaches your brain at once. Many people find the taste of the powder unpleasant.

Taking It Orally

This study found that taking Noopept orally allows it to become absorbed in the intestines, enter the bloodstream and cross the blood-brain barrier (BBB) unaffected. However, everyone’s digestive system is different. Some enzymes may metabolize the peptides from Noopept more than others, altering its absorption. Some users find it better to take it in a stack that also contains Choline.

Many people find that administration is more pleasant when ingested orally. However, depending on the pill, it may be difficult to divide it into the proper dosage without a scale.

Taking it Before Bed

Your brain uses the period of slow-wave sleep (SWS) to consolidate memory. During this restorative time, acetylcholine levels must drop. Low cholinergic tone during this phase of sleep allows new memories to be stored in long-term memory centers in the brain.

If you take Noopept before bed, you’ll increase the levels of acetylcholine in the brain, disrupting the restorative and memory-consolidation benefits of slow-wave sleep. Although some users say that taking Noopept before bed can improve the quality of their dreams, it can interfere with long-term memory.

Buy Noopept and Forms

If you’re a new user looking for Noopept online, you might be overwhelmed by the offerings. Noopept is available as a pill, capsule or powder.

Noopept Capsules & Pills

Capsules and pills are convenient. The dosage is pre-measured, and they’re easy to bring out and about with you to take throughout the day. If you’re splitting up your dosage or taking a very small dose, however, it may be difficult to split a pill or capsule. If you already know how much Noopept you need to take per dose, you may find a capsule or pill more suitable.

Some capsules come pre-stacked with choline, however. This adds to the convenience of this form of the supplement.

Noopept Liquid

Science.Bio offers Noopept in a liquid form. The advance of liquid is that you can just drop a little bit in your coffeee and you don’t need to worry about swallowing those larger pills and getting that lumpy throat feeling!

Noopept Review and Stacks (Updated 2022)

Noopept Powder

The supplement is more potent in powdered form, because it can more easily be administered sublingually.

Noopept Review and Stacks (Updated 2022)

Noopept Choline Stack

Choline is a nutrient that’s essential for cellular function. Research shows that it plays a large role in memory creation and brain function. Choline supplementation in the diet provides neuroprotective benefits.

Taking choline with Noopept can boost its brain-enhancing power. Different types of choline are available, however. Alpha GPC and Citicoline (CDP choline) are more bioavailable than other forms of choline, like choline bitartrate and PhosphatidylCholine.

When stacking Noopept with Alpha GPC, the recommended dosage is 1:20 Noopept to Alpha GPC. When stacking with Citicoline, a 1:30 dosage ratio is recommended.

If you’re a new Noopept user, you may want to start by taking the Nootropic alone. Assess its effectiveness and results before stacking with choline.

Comparison To Other Nootropics

Although all nootropics are touted as improving cognitive function in some way, they are all slightly different. Some people respond better to some than others. The best way to determine which one is right for you is to create a baseline of your cognitive function before taking a nootropic and experiment with different formulas and doses.

Noopept vs. Piracetam

Noopept is considered to be a more potent version of Piracetam, which may also be available under the name Nootropil. Both drugs are therapeutic for cognitive deficits such as memory loss and neurosis-like symptoms. However, Noopept has been found to provide more balanced effects. Piracetam is associated with more side effects. It also has more of a psychostimulatory effect than Noopept. This can make users feel more jittery and excitable.

You don’t have to take as much Noopept to get the same effects as Piracetam. explains that while the recommended dose of Piracetam is 4800 mg, the standard dose of Noopept is typically 10 to 30 mg.

Noopept vs. Aniracetam

Aniracetam is slightly stronger than Piracetam but not as strong as Noopept. Aniracetam works on GABA receptors, promoting the increase of feel-good neurotransmitters dopamine and serotonin. Because of this, Aniracetam is often used for its mood-enhancing benefits. It is being studied for its use in treating mood disorders, such as depression.

Noopept modulates glutamate, a neurotransmitter that is important for memory and learning functions in the brain. Aniracetam binds to acetylcholine receptor sites, preventing the breakdown of the neurotransmitter so that the effects last longer.

Noopept vs. Pramiracetam

Like Noopept, Pramiracetam is used to improve general brain function. However, unlike with Noopept, no mood-enhancing benefits have been associated with Pramiracetam use. Because it can improve your focus, motivation, thought processes and sensory sensitivity without additional effects, Pramiracetam is sometimes referred to as a “pure” nootropic.

More side effects are typically reported with the use of Pramiracetam. These include:

  • Headache
  • Stomach upset
  • Anxiety
  • Insomnia
  • Fatigue

Noopept vs. Modafinil

Modafinil is only available with a prescription in the United States, Australia and many other countries. It is typically prescribed for narcolepsy and other sleep disorders. Modafinil has been studied as a treatment for ADHD.

Because it also can improve energy, focus and mental performance, Modafinil is often used by students and other people who want to enhance their brain function. It targets the dopaminergic system, which helps improve learning and memory. Users report that Modafinil can also suppress appetite, which can help users lose weight.

Modafinil may cause more side effects than Noopept. It may also interact negatively with other medications.

Noopept vs. Adrafinil

Adrafinil is a non-regulated version of Modafinil. Like Noopept, it does not require a prescription and can be legally purchased online. Adrafinil converts to Modafinil in the liver. This can put stress on the liver and cause a buildup of liver enzymes.

Adrafinil should not be taken with other medications or with alcohol. It should not be taken by people with liver or kidney problems. Adrafinil must be cycled to protect the liver and kidneys from damage.

Noopept vs. Adderall

Adderall is an amphetamine. Both Adderall and Noopept have psychostimulant properties and can improve energy. Adderall can also improve attention and focus by releasing monoamine stores within the neurons. In lower doses, it can be a helpful enhancement to improve working memory.

However, in larger doses, Adderall can cause euphoria. This can be distracting and take away from its benefits for attention and concentration. Noopept should not cause overexcitement or euphoria.

Noopept vs. Phenylpiracetam

Noopept and Phenylpiracetam are both more potent than most other racetams. One of the main differences is that Phenylpiracetam has marked benefits for improving physical energy. Some users claim that the combination of cognitive enhancement and energy improvement achieved with Phenylpiracetam is similar to the boost provided by Adderall.

Noopept isn’t known for its energy-boosting properties. It is more often correlated with better thought processes and mood enhancement. If you’re looking for a supplement that offers general cognitive enhancement for your daily life, Noopept might be preferable. If you’re seeking a pill that will help you stay awake and study for a test, Phenylpiracetam may be more suitable.


Noopept is one of the most popular nootropics. It’s one of the strongest nootropics available. Because you can achieve results with smaller doses, it tends to be one of the more cost-effective nootropics as well.

Noopept activates the areas of the brain that are responsible for learning, memory and recall. It has been studied mainly in patients with Alzheimer’s disease and has been found to reverse certain types of brain damage.

Although it has also been associated with relaxing and mood-enhancing effects, Noopept is used primarily as a cognitive enhancer. It shouldn’t ramp up your energy or make you feel jittery. It should simply help you focus on what you’re doing and complete mentally demanding tasks more easily.

Still Have Questions?

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Nicole Gleichman

Nicole Gleichmann is an avid self-improvement enthusiast who loves to help her readers become the best versions of themselves. For the past five years, she's dedicated her life as a wellness writer and nutrition coach to learning everything there is to know about human potential. In her free time, she spends her days traversing the mountains, playing with her dogs, and traveling the world in search of new perspectives.
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