11 In the index

Enclomiphene ENCLO

A component of an older fertility drug, studied specifically for raising testosterone in men with low hormone levels while still allowing them to remain fertile, unlike testosterone replacement itself. Clinical trials support that it raises testosterone effectively while preserving sperm production, though it's used off-label in the U.S. while awaiting full approval for this specific use.

Also known as Enclomifene, trans-Clomiphene, trans-Clomifene, Enclomifeno, Enclomifenum, RMI 16,289, ISOMER B

Effects Hormonal

Routes Oral

Legal status Prescription drug

WADA Banned at all times

3D Molecular Structure of C₂₆H₂₈ClNO

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Chemistry

Formula: C26H28ClNO
Molar mass: 406.0
CAS: 15690-57-0
PubChem CID: 1548953
IUPAC name: 2-[4-[(E)-2-chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethylethanamine
InChIKey: GKIRPKYJQBWNGO-OCEACIFDSA-N

Reported dosing

Clinical data

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 12.5-25 mg/day

Reported range 6.25-25 mg/day

Route Oral

Frequency Once daily

Duration Ongoing, as prescribed off-label for low testosterone

The trans-isomer of clomiphene; used off-label (largely through telehealth clinics) to raise natural testosterone without the estrogenic isomer found in Clomid. Not separately FDA-approved as its own branded product for this use in the US.

Where this comes from Clinical trials (male hypogonadism studies); off-label telehealth-prescribing patterns

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.