270 In the index

Yohimbine YOH

A plant-derived compound historically used for erectile dysfunction before newer drugs came along, now more popular as a stubborn-fat-loss aid. Human studies support modest effects for both uses, but it commonly causes anxiety and raises heart rate and blood pressure, especially at higher doses or combined with stimulants.

Also known as Yohimbe extract, Yohimbin, Quebrachine, Corynine, Quebrachin, APHRODINE, Yohimbic acid methyl ester, (+)-Yohimbine

Effects Libido Lose fat

Routes Oral

Legal status Dietary supplement

WADA Not listed

3D Molecular Structure of C₂₁H₂₆N₂O₃

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Chemistry

Formula: C21H26N2O3
Molar mass: 354.4
CAS: 146-48-5
PubChem CID: 8969
IUPAC name: methyl (1S,15R,18S,19R,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
InChIKey: BLGXFZZNTVWLAY-SCYLSFHTSA-N

Reported dosing

Limited data

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 5.4 mg per dose

Reported range 5.4-20 mg/day

Route Oral

Frequency 1-3 times daily, typically before fasted training

Duration Not established for chronic use

A plant-derived compound historically used for erectile dysfunction, now more popular as a stubborn-fat-loss aid; commonly causes anxiety and raises heart rate and blood pressure, especially at higher doses or combined with stimulants.

Where this comes from Clinical pharmacology studies; supplement-industry dosing

Human data for this compound is limited. Read the figures above as a record of reported use rather than established dosing.

Variants

Name	Abbr	Route	Notes
Yohimbine HCl	YOH-H	Oral	The standardised salt used in fat-loss products.