242 In the index

Synephrine SYNE

A stimulant compound from bitter orange, commonly found in commercial fat-burner supplements as a substitute for banned stimulants. Human studies show modest effects on metabolism, but it can raise heart rate and blood pressure, especially when combined with caffeine.

Also known as Bitter orange, p-synephrine

Effects Lose fat

Routes Oral

Legal status Dietary supplement

WADA Not listed

3D Molecular Structure of C₉H₁₃NO₂

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Chemistry

Formula: C9H13NO2
Molar mass: 167.20
CAS: 94-07-5
PubChem CID: 7172

Reported dosing

Limited data

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 20-50 mg per dose

Reported range 20-100 mg/day

Route Oral

Frequency 1-2 times daily (pre-workout/fat-burner use)

Duration Not established for chronic use

A bitter-orange-derived stimulant compound found in many fat-burner/pre-workout supplements; can raise heart rate and blood pressure, particularly when combined with caffeine.

Where this comes from Limited clinical pharmacology studies; supplement-industry dosing

Human data for this compound is limited. Read the figures above as a record of reported use rather than established dosing.