236 In the index

Spermidine SPER

A natural compound found in foods like wheat germ and aged cheese, studied in human trials for its role in cellular cleanup processes tied to aging and heart health. Studies show modest improvements in some aging-related and heart markers, though large, long-term human outcome studies are still limited.

Also known as Spermidine trihydrochloride, 1,5,10-Triazadecane, 4-Azaoctamethylenediamine, 4-Azaoctane-1,8-diamine, Spermidin, N-(3-aminopropyl)butane-1,4-diamine, N-(3-Aminopropyl)-1,4-butanediamine, 1,8-Diamino-4-azaoctane

Effects Longevity

Routes Oral

Legal status Dietary supplement

WADA Not listed

3D Molecular Structure of C₇H₁₉N₃

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Chemistry

Formula: C7H19N3
Molar mass: 145.25
CAS: 124-20-9
PubChem CID: 1102
IUPAC name: N'-(3-aminopropyl)butane-1,4-diamine
InChIKey: ATHGHQPFGPMSJY-UHFFFAOYSA-N

Reported dosing

Clinical data

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 1-6 mg/day

Reported range 1-15 mg/day

Route Oral

Frequency Once daily

Duration Ongoing (supplement use)

Sold as a dietary supplement marketed for autophagy/longevity support; human trial evidence for meaningful clinical benefit at supplement doses is still early-stage.

Where this comes from Early-phase clinical trials; supplement-industry dosing

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.