269 In the index

Rauwolscine RAUW

A plant-derived compound closely related to yohimbine, marketed in fat-loss supplements as a way to target stubborn fat. There's much less human research on it than on yohimbine itself — most of what's claimed rests on their shared mechanism rather than dedicated study.

Also known as Alpha-yohimbine, Corynanthidine, Isoyohimbine, Mesoyohimbine, T4LJ7LU45W, CHEBI:48562, RefChem:930571

Effects Lose fat

Routes Oral

Legal status Dietary supplement

WADA Not listed

3D Molecular Structure of C₂₁H₂₆N₂O₃

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Chemistry

Formula: C21H26N2O3
Molar mass: 354.4
CAS: 131-03-3
PubChem CID: 643606
IUPAC name: methyl (1S,15S,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate
InChIKey: BLGXFZZNTVWLAY-DIRVCLHFSA-N

Reported dosing

Limited data

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 1-2 mg per dose

Reported range 1-4 mg per dose

Route Oral

Frequency 1-2 times daily

Duration Not established for chronic use

An alpha-2 blocker closely related to yohimbine, sold as a fat-loss supplement; commonly causes anxiety and elevated heart rate/blood pressure, especially at higher doses.

Where this comes from Limited clinical pharmacology studies; supplement-industry dosing

Human data for this compound is limited. Read the figures above as a record of reported use rather than established dosing.