271 In the index

Pioglitazone PIO

An FDA-approved diabetes medication that helps the body use its own insulin more effectively. Human studies confirm real blood sugar benefits, balanced against known risks of fluid retention, weight gain, and a higher chance of heart failure in people already prone to it.

Also known as Actos, Glustin, Zactos, Pioglitazona, Pioglitazonum, CHEBI:8228, X4OV71U42S, U-72107

Effects Longevity

Routes Oral

Legal status Prescription drug

WADA Not listed

3D Molecular Structure of C₁₉H₂₀N₂O₃S

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Chemistry

Formula: C19H20N2O3S
Molar mass: 356.4
CAS: 111025-46-8
PubChem CID: 4829
IUPAC name: 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
InChIKey: HYAFETHFCAUJAY-UHFFFAOYSA-N

Reported dosing

Approved label

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 15-30 mg/day

Reported range 15-45 mg/day

Route Oral

Frequency Once daily

Duration Chronic/ongoing (as prescribed)

FDA-approved thiazolidinedione (Actos) for type 2 diabetes; carries warnings for fluid retention/heart failure and bone-fracture risk.

Where this comes from FDA prescribing information

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.