267 In the index

Naltrexone NTX

An FDA-approved medication for alcohol and opioid addiction, also studied off-label at very low doses for chronic pain and autoimmune conditions. Its addiction-treatment use is strongly proven; the low-dose off-label use has smaller, earlier-stage human research behind it.

Also known as Revia, low-dose naltrexone

Effects Heal Lose fat

Routes Oral

Legal status Prescription drug

WADA Not listed

3D Molecular Structure of C₂₀H₂₃NO₄

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Chemistry

Formula: C20H23NO4
Molar mass: 341.4
CAS: 16590-41-3
PubChem CID: 5360515

Reported dosing

Approved label

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 50 mg/day (standard) or 1.5-4.5 mg/day (low-dose, off-label)

Reported range 1.5-50 mg/day depending on use case

Route Oral

Frequency Once daily

Duration Chronic/ongoing (as prescribed)

FDA-approved for alcohol and opioid dependence (ReVia/Vivitrol) at standard doses; 'low-dose naltrexone' for chronic pain/autoimmune conditions is a widely practiced off-label use with growing but still-limited trial evidence.

Where this comes from FDA prescribing information; off-label clinical use patterns

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.