234 In the index

Metformin MET

An FDA-approved first-choice medication for type 2 diabetes that helps the body respond better to its own insulin. Decades of research confirm it's safe and effective, and it's now being studied in a major human trial specifically for its potential to slow down aging itself.

Also known as Glucophage, 1,1-Dimethylbiguanide, N,N-dimethylimidodicarbonimidic diamide, Metiguanide, Dimethylbiguanide, Metformine, N,N-Dimethylbiguanide, Metformina

Effects Longevity Lose fat

Routes Oral

Legal status Prescription drug

WADA Not listed

3D Molecular Structure of C₄H₁₁N₅

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Chemistry

Formula: C4H11N5
Molar mass: 129.16
CAS: 657-24-9
PubChem CID: 4091
IUPAC name: 3-(diaminomethylidene)-1,1-dimethylguanidine
InChIKey: XZWYZXLIPXDOLR-UHFFFAOYSA-N

Reported dosing

Approved label

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 500-1000 mg twice daily

Reported range 500-2550 mg/day

Route Oral

Frequency 1-3 times daily, with meals

Duration Chronic/ongoing (as prescribed)

FDA-approved first-line medication for type 2 diabetes; also studied experimentally for longevity, though that use is not an approved indication.

Where this comes from FDA prescribing information

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.