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Pharmaceuticals / Metabolic and glucose

278 In the index

Canagliflozin CANA

An FDA-approved diabetes drug that works by having the kidneys flush out excess sugar in urine. Large human studies show it lowers blood sugar, causes modest weight loss, and protects the heart and kidneys, though it can increase the risk of genital infections.

Also known as Invokana, Canagliflozin anhydrous, 6S49DGR869, CHEBI:73274, Canagliflozina, Canagliflozine, Canagliflozin, Anhydrous

Routes Oral
Legal status Prescription drug
WADA Not listed

3D Molecular Structure of C24H25FO5S

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  • Carbon
  • Hydrogen
  • Fluorine
  • Oxygen
  • Sulfur

Chemistry

Formula
C24H25FO5S
Molar mass
444.5
CAS
842133-18-0
PubChem CID
24812758
IUPAC name
(2S,3R,4R,5S,6R)-2-[3-[[5-(4-fluorophenyl)thiophen-2-yl]methyl]-4-methylphenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
InChIKey
XTNGUQKDFGDXSJ-ZXGKGEBGSA-N

Reported dosing

Approved label

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 100 mg
Reported range 100-300 mg/day
Route Oral
Frequency Once daily, before the first meal
Duration Chronic/ongoing (as prescribed)

FDA-approved prescription medication (Invokana) for type 2 diabetes; carries warnings for genital infections and, rarely, ketoacidosis.

Where this comes from FDA prescribing information

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.