265 In the index

Berberine BERB

A plant compound nicknamed 'nature's Ozempic' online for its reputation as a blood-sugar helper. Human studies show it modestly improves blood sugar, cholesterol, and insulin response, but the effect is much smaller than real prescription drugs like Ozempic, and it commonly causes stomach upset.

Also known as Berberine HCl, Umbellatine, Berberin, Berbericine, Majarine, Thalsine, Umbellatin, Berberone

Effects Longevity Lose fat

Routes Oral

Legal status Dietary supplement

WADA Not listed

3D Molecular Structure of C₂₀H₁₈NO₄+

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Chemistry

Formula: C20H18NO4+
Molar mass: 336.4
CAS: 2086-83-1
PubChem CID: 2353
IUPAC name: 16,17-dimethoxy-5,7-dioxa-13-azoniapentacyclo[11.8.0.02,10.04,8.015,20]henicosa-1(13),2,4(8),9,14,16,18,20-octaene
InChIKey: YBHILYKTIRIUTE-UHFFFAOYSA-N

Reported dosing

Clinical data

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 500 mg per dose

Reported range 500-1500 mg/day

Route Oral

Frequency 2-3 times daily with meals

Duration Ongoing (supplement use)

Sold as a dietary supplement; well-studied for glucose and lipid effects in clinical trials, though not FDA-approved as a drug.

Where this comes from Clinical trials (multiple RCTs); supplement-industry dosing

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.