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Peptides / Longevity and mitochondrial peptides

157 In the index

MOTS-c MOTS

A peptide made inside the body's cellular energy factories, studied as an 'exercise in a shot' for improving metabolism in mouse studies. Small early human trials are underway, but there's much less proof in people so far than in mice.

Also known as Mitochondrial ORF of the 12S rRNA, MOTS-c (human) (trifluoroacetate salt), A5CV6JFB78, H-MRWQEMGYIFYPRKLR-OH, orb2279120, orb3032863, Mitochondria-derived peptide mots-c, EX-A6267

Effects Longevity Lose fat
Routes Subcutaneous
Legal status Research chemical
WADA Not listed

Molecular Structure of C101H152N28O22S2

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  • Carbon
  • Hydrogen
  • Nitrogen
  • Oxygen
  • Sulfur

PubChem has no 3D conformer for this molecule, so this is the flat structure.

Chemistry

Formula
C101H152N28O22S2
Molar mass
2174.6
CAS
1627580-64-6
PubChem CID
146675088
IUPAC name
(4S)-4-[[(2S)-5-amino-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-4-methylsulfanylbutanoyl]amino]-5-carbamimidamidopentanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-5-oxopentanoyl]amino]-5-[[(2S)-1-[[2-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[(2S)-2-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(1S)-4-carbamimidamido-1-carboxybutyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-2-oxoethyl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-5-oxopentanoic acid
InChIKey
WYTHCOXVWRKRAH-LOKRTKBUSA-N

Reported dosing

User-reported

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 5-10 mg/week
Reported range 5-15 mg/week, divided into 2-3 injections
Route Subcutaneous injection
Frequency 2-3 times weekly
Duration 4-8 week course (unregulated use)

A mitochondrial-derived peptide studied for metabolic/exercise-mimetic effects; not FDA-approved, sold only as a research chemical with dosing extrapolated from animal studies.

Where this comes from Animal studies only; user-reported/research-chemical vendor literature

There is no approved human dosing for this compound. The figures above are what users and vendors report, not what has been established as safe or effective. Treat them as a record of what is done, not as guidance.