117 In the index

Matrixyl MATRX

A peptide used in anti-aging skin creams for boosting collagen and smoothing wrinkles. Cosmetic studies, mostly funded by ingredient makers, report modest improvements in skin texture and fine lines with regular topical use.

Also known as Palmitoyl pentapeptide-4, Palmitoyl pentapeptide-3, Oristar popp, Lipopentapeptide 3, PAL-Lys-Thr-Thr-Lys-Ser, Palmitoyl pentapeptide-4 [INCI], RefChem:858432, 606-757-9

Effects Skin and hair

Routes Topical

Legal status Dietary supplement

WADA Not listed

Molecular Structure of C₃₉H₇₅N₇O₁₀

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PubChem has no 3D conformer for this molecule, so this is the flat structure.

Chemistry

Formula: C39H75N7O10
Molar mass: 802.1
CAS: 214047-00-4
PubChem CID: 9897237
IUPAC name: (2S)-2-[[(2S)-6-amino-2-[[(2S,3R)-2-[[(2S,3R)-2-[[(2S)-6-amino-2-(hexadecanoylamino)hexanoyl]amino]-3-hydroxybutanoyl]amino]-3-hydroxybutanoyl]amino]hexanoyl]amino]-3-hydroxypropanoic acid
InChIKey: WSGCRSMLXFHGRM-DEVHWETNSA-N

Reported dosing

Limited data

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose Topical concentration of roughly 3-5% in serum

Reported range Manufacturer formulations vary

Route Topical

Frequency Once or twice daily

Duration Ongoing (cosmetic use)

A widely used cosmetic peptide ingredient (palmitoyl pentapeptide) marketed for collagen support; evidence is mostly from manufacturer-sponsored studies.

Where this comes from Manufacturer-sponsored cosmetic studies

Human data for this compound is limited. Read the figures above as a record of reported use rather than established dosing.