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Peptides / GHRPs and ghrelin agonists

165 In the index

Ghrelin GHRL

The body's natural 'hunger hormone,' which also triggers growth hormone release, studied in humans through controlled hospital infusions. Studies confirm it reliably makes people hungrier and boosts growth hormone, which is why it's of interest for treating conditions that cause severe appetite loss.

Also known as Lenomorelin, Gastric MLTRP, CHEBI:75431, Ppghrelin, Ghrelin Precursor, Precursor, Ghrelin, PpMTLRP, Motilin Related Peptide, Appetite Regulating Hormone

Molecular Structure of C149H249N47O42

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  • Carbon
  • Hydrogen
  • Nitrogen
  • Oxygen

PubChem has no 3D conformer for this molecule, so this is the flat structure.

Chemistry

Formula
C149H249N47O42
Molar mass
3370.9
CAS
304853-26-7
PubChem CID
16133832
IUPAC name
(4S)-4-[[(2S)-1-[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-[(2-aminoacetyl)amino]-3-hydroxypropanoyl]amino]-3-octanoyloxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]-3-hydroxypropanoyl]pyrrolidine-2-carbonyl]amino]-5-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-6-amino-1-[(2S)-2-[(2S)-2-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-5-amino-1-[(2S)-2-[[(1S)-4-carbamimidamido-1-carboxybutyl]carbamoyl]pyrrolidin-1-yl]-1,5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carbonyl]pyrrolidin-1-yl]-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-carboxy-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-3-(1H-imidazol-4-yl)-1-oxopropan-2-yl]amino]-5-oxopentanoic acid
InChIKey
GNKDKYIHGQKHHM-RJKLHVOGSA-N

Reported dosing

Clinical data

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose Not established for general use; primarily a research/diagnostic agent
Reported range Clinical research doses: roughly 1-5 mcg/kg IV
Route Intravenous injection
Frequency Single or repeated research-protocol dosing
Duration Not established for chronic use

The natural 'hunger hormone,' used mainly in endocrine research settings rather than as a marketed product; not sold as an approved drug.

Where this comes from Published clinical research studies

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.