118 In the index

Dermorphin DERM

An extremely powerful pain-relieving substance originally found in frog skin, notorious as an illegal doping agent in horse racing. It has never been studied or used safely in humans, and being far stronger than morphine, it carries a serious risk of fatal overdose.

Also known as Dermorphin, H-Tyr-D-ala-phe-gly-tyr-pro-ser-NH2, 2SEC01B703, RefChem:132075, DERMORPHIN ACETATE, Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2, Dermorphin?, YAFGYPS-NH2

Effects Heal

Routes Subcutaneous

Legal status Research chemical

WADA Banned at all times

Molecular Structure of C₄₀H₅₀N₈O₁₀

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PubChem has no 3D conformer for this molecule, so this is the flat structure.

Chemistry

Formula: C40H50N8O10
Molar mass: 802.9
CAS: 77614-16-5
PubChem CID: 5485199
IUPAC name: (2S)-N-[(2S)-1-amino-3-hydroxy-1-oxopropan-2-yl]-1-[(2S)-2-[[2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-3-phenylpropanoyl]amino]acetyl]amino]-3-(4-hydroxyphenyl)propanoyl]pyrrolidine-2-carboxamide
InChIKey: FHZPGIUBXYVUOY-VWGYHWLBSA-N

Reported dosing

Limited data

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose Not established for humans; extremely potent opioid peptide

Reported range No safe human dosing data; famous in horse-racing doping (as 'frog juice') at microgram-level veterinary doses

Route Injection (veterinary/illicit use)

Frequency Not established

Duration Not established

An extremely potent, frog-skin-derived opioid peptide with no legitimate human medical use; associated with veterinary doping scandals and carries serious overdose/respiratory-depression risk. Included for informational purposes only, not as a usage guide.

Where this comes from Veterinary doping-control literature; no human clinical data

Human data for this compound is limited. Read the figures above as a record of reported use rather than established dosing.