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Nootropics / Racetams and ampakines

75 In the index

PRL-8-53 PRL

An obscure compound from a 1970s patent, tested in just one small human study that reported better memory recall. That single limited study is essentially the entire evidence base — there's been no modern follow-up or safety testing.

Also known as PRL-8-53

Effects Focus
Routes Oral
Legal status Research chemical
WADA Not listed

Molecular Structure of C18H22ClNO2

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  • Carbon
  • Hydrogen
  • Chlorine
  • Nitrogen
  • Oxygen

PubChem has no 3D conformer for this molecule, so this is the flat structure.

Chemistry

Formula
C18H22ClNO2
Molar mass
319.8
CAS
51352-87-5
PubChem CID
70700868

Reported dosing

User-reported

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 5 mg
Reported range 2.5-20 mg/day
Route Oral
Frequency Once daily
Duration Not established; some users report only intermittent dosing due to reported tolerance

A little-studied experimental nootropic from a single small 1970s human trial; sold as a research chemical with essentially no modern safety data.

Where this comes from Single small historical clinical study; user-reported/research-chemical vendor literature

There is no approved human dosing for this compound. The figures above are what users and vendors report, not what has been established as safe or effective. Treat them as a record of what is done, not as guidance.