44 In the index

Phenibut PHENI

A calming compound developed in Russia and used there as an approved anxiety medication. Outside Russia it's sold as an unregulated anxiety and sleep aid, and there are real, documented cases of people becoming dependent on it with a difficult withdrawal when stopping.

Also known as Beta-phenyl-GABA, 4-Amino-3-phenylbutanoic acid, Fenibut, 4-Amino-3-phenylbutyric acid, PhGaba, phenigamma, phenygam, beta-(Aminomethyl)benzenepropanoic acid

Effects Mood Sleep

Routes Oral

Legal status Unscheduled

WADA Not listed

3D Molecular Structure of C₁₀H₁₃NO₂

Drag to rotate · scroll to zoom

Chemistry

Formula: C10H13NO2
Molar mass: 179.22
CAS: 1078-21-3
PubChem CID: 14113
IUPAC name: 4-amino-3-phenylbutanoic acid
InChIKey: DAFOCGYVTAOKAJ-UHFFFAOYSA-N

Reported dosing

Limited data

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 250-500 mg

Reported range 250 mg-2 g per dose

Route Oral

Frequency 1-3 times daily, with mandatory tolerance-break periods recommended by users

Duration Short-term use strongly recommended due to rapid tolerance and a recognized dependence/withdrawal risk

Approved as a prescription anxiolytic in Russia; not FDA-approved and not legal to sell as a dietary supplement ingredient in the US per FDA warning letters. Carries a real risk of dependence and a difficult, sometimes dangerous withdrawal syndrome with regular use.

Where this comes from Russian-language clinical studies; FDA warning-letter literature; case reports

Human data for this compound is limited. Read the figures above as a record of reported use rather than established dosing.