58 In the index

Huperzine A HUP-A

A plant-derived compound from Chinese club moss, studied in human trials (mostly done in China) for memory and thinking. Trials suggest modest cognitive benefits, especially with age-related decline, though it can cause stomach-related side effects and hasn't gone through large Western-standard trials.

Also known as Huperzia serrata extract, (-)-huperzine A, (-)-huperazine A, L-huperzine A, Huperzine-A, Hup A, Kimpukan A, CHEBI:78330

Effects Focus

Routes Oral

Legal status Dietary supplement

WADA Not listed

3D Molecular Structure of C₁₅H₁₈N₂O

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Chemistry

Formula: C15H18N2O
Molar mass: 242.32
CAS: 102518-79-6
PubChem CID: 854026
IUPAC name: (1R,9R,13E)-1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one
InChIKey: ZRJBHWIHUMBLCN-YQEJDHNASA-N

Reported dosing

Clinical data

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 50-200 mcg/day

Reported range 50-400 mcg/day

Route Oral

Frequency Once or twice daily

Duration Ongoing (supplement use), often cycled due to acetylcholinesterase downregulation with continuous use

Sold as a dietary supplement in the US; a prescription drug in China for Alzheimer's disease.

Where this comes from Clinical trials (China); supplement-industry dosing

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.