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Hormones / Pituitary and posterior hormones

32 In the index

Vasopressin AVP

An FDA-approved hormone medication used for a rare thirst-and-urination disorder and, in intensive care, for dangerously low blood pressure from severe illness. Extensive clinical data support both uses, with fluid and electrolyte levels needing to be monitored during treatment.

Also known as Antidiuretic hormone, ARGIPRESSIN, Argipressine, Arginine vasopressin, Vasopressin injection, Argipresina, Argipressina, Argipressinum, 8-Arginine-vasopressin

Effects Hormonal
Routes Injectable Nasal
Legal status Prescription drug
WADA Banned at all times

Molecular Structure of C46H65N15O12S2

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  • Carbon
  • Hydrogen
  • Nitrogen
  • Oxygen
  • Sulfur

PubChem has no 3D conformer for this molecule, so this is the flat structure.

Chemistry

Formula
C46H65N15O12S2
Molar mass
1084.2
CAS
113-79-1
PubChem CID
644077
IUPAC name
(2S)-1-[(4R,7S,10S,13S,16S,19R)-19-amino-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]-N-[(2S)-1-[(2-amino-2-oxoethyl)amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]pyrrolidine-2-carboxamide
InChIKey
KBZOIRJILGZLEJ-LGYYRGKSSA-N

Reported dosing

Approved label

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 5-10 units per dose (diabetes insipidus) or 0.01-0.04 units/min infusion (septic shock)
Reported range Highly protocol-specific by indication
Route Subcutaneous, IM, or IV infusion
Frequency 2-4 times daily (diabetes insipidus) or continuous infusion (critical care)
Duration Chronic/ongoing (diabetes insipidus) or short-term ICU use (septic shock)

FDA-approved prescription hormone medication; used for a rare thirst/urination disorder and, in intensive care, for dangerously low blood pressure from severe illness. Fluid and electrolyte levels require monitoring during treatment.

Where this comes from FDA prescribing information

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.