240 In the index

Nicotine NIC

A well-studied stimulant found in tobacco, available in FDA-approved quit-smoking products like patches and gum. Its approved use for quitting smoking is well supported, and its addictive potential and effects on the heart are also extensively documented.

Also known as Nicotine pouches, patches, L-Nicotine, (-)-Nicotine, (S)-Nicotine, (S)-3-(1-methylpyrrolidin-2-yl)pyridine, (S)-(-)-Nicotine, Habitrol, Nicotrol

Effects Focus Lose fat

Routes Oral Topical

Legal status Unscheduled

WADA Monitored

3D Molecular Structure of C₁₀H₁₄N₂

Drag to rotate · scroll to zoom

Chemistry

Formula: C10H14N2
Molar mass: 162.23
CAS: 54-11-5
PubChem CID: 89594
IUPAC name: 3-[(2S)-1-methylpyrrolidin-2-yl]pyridine
InChIKey: SNICXCGAKADSCV-JTQLQIEISA-N

Reported dosing

Approved label

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 2-4 mg per dose (gum/lozenge, smoking-cessation use)

Reported range 2-4 mg per piece, up to 24 pieces/day maximum; patch doses of 7-21 mg/day

Route Oral (gum/lozenge), transdermal (patch), or inhaled (vaporized/smoked)

Frequency As needed (gum/lozenge) or once daily (patch)

Duration Typically tapered over 8-12 weeks for smoking cessation

FDA-approved in smoking-cessation products; also used off-label in low doses as a cognitive stimulant, though nicotine itself is addictive and its non-cessation recreational/vaporized use carries its own health risks.

Where this comes from FDA prescribing information (cessation products)

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.