241 In the index

Ephedrine EPHED

An approved decongestant that, combined with caffeine, has a long history of use for weight loss and athletic performance. Human studies confirm real fat-burning and appetite-suppressing effects, but the resulting rise in heart rate and blood pressure led U.S. regulators to restrict similar plant-based supplements.

Also known as Ephedra alkaloid, l-Ephedrine, (-)-Ephedrine, Ephedrin, Mandrin, Ephedrol, Sanedrine, L(-)-Ephedrine

Effects Endurance Lose fat

Routes Oral

Legal status Prescription drug

WADA Banned in-competition

3D Molecular Structure of C₁₀H₁₅NO

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Chemistry

Formula: C10H15NO
Molar mass: 165.23
CAS: 299-42-3
PubChem CID: 9294
IUPAC name: (1R,2S)-2-(methylamino)-1-phenylpropan-1-ol
InChIKey: KWGRBVOPPLSCSI-WPRPVWTQSA-N

Reported dosing

Limited data

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 20-25 mg per dose

Reported range 20-50 mg per dose, up to 150 mg/day short-term

Route Oral

Frequency 2-3 times daily

Duration Short-term use (days to a few weeks) recommended due to tolerance and cardiovascular risk

Restricted/behind-the-counter in the US due to methamphetamine-precursor regulations; classic 'ECA stack' component (with caffeine and aspirin) for fat loss, carries cardiovascular risk.

Where this comes from FDA/DEA regulatory literature; clinical pharmacology studies

Human data for this compound is limited. Read the figures above as a record of reported use rather than established dosing.