59 In the index

Agomelatine AGO

An antidepressant approved in Europe that works partly by mimicking the body's sleep hormone, melatonin. Clinical trials support that it treats depression effectively with fewer sexual side effects than common antidepressants, though it requires occasional liver monitoring because of rare liver problems.

Also known as Valdoxan, Thymanax, S20098, S-20098, S 20098, Agomelatina, 137R1N49AD

Effects Mood Sleep

Routes Oral

Legal status Prescription drug

WADA Not listed

3D Molecular Structure of C₁₅H₁₇NO₂

Drag to rotate · scroll to zoom

Chemistry

Formula: C15H17NO2
Molar mass: 243.30
CAS: 138112-76-2
PubChem CID: 82148
IUPAC name: N-[2-(7-methoxynaphthalen-1-yl)ethyl]acetamide
InChIKey: YJYPHIXNFHFHND-UHFFFAOYSA-N

Reported dosing

Approved label

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 25 mg

Reported range 25-50 mg/day

Route Oral

Frequency Once daily (at bedtime)

Duration Chronic/ongoing (as prescribed)

Approved in the EU and other countries as an antidepressant (Valdoxan) but not FDA-approved in the US; requires liver function monitoring.

Where this comes from EMA prescribing information; clinical trials

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.