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Peptides / GHRH analogues

163 In the index

Mod GRF 1-29 ModGRF

A stabilized version of a natural hormone-releasing signal, used in research-peptide circles to trigger short bursts of growth hormone. Small studies confirm it does raise growth hormone briefly, but it hasn't gone through the full testing needed for approval.

Also known as CJC-1295 no DAC, SERMORELIN, Sermorelina, Sermoreline, Sermorelinum, 89243S03TE, CHEBI:9118, Groliberin, hGHRH(1-29)NH2

Molecular Structure of C149H246N44O42S

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  • Carbon
  • Hydrogen
  • Nitrogen
  • Oxygen
  • Sulfur

PubChem has no 3D conformer for this molecule, so this is the flat structure.

Chemistry

Formula
C149H246N44O42S
Molar mass
3357.9
CAS
86168-78-7
PubChem CID
16132413
IUPAC name
(3S)-4-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S,3R)-1-[[(2S)-4-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[2-[[(2S)-5-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-6-amino-1-[[(2S)-1-[[(2S)-1-[[(2S)-5-amino-1-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-amino-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-methylsulfanyl-1-oxobutan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-carboxy-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-2-oxoethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]amino]-1-oxohexan-2-yl]amino]-5-carbamimidamido-1-oxopentan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1,4-dioxobutan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-3-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]propanoyl]amino]-4-oxobutanoic acid
InChIKey
WGWPRVFKDLAUQJ-MITYVQBRSA-N

Reported dosing

User-reported

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 100-300 mcg per dose
Reported range 100-300 mcg per dose
Route Subcutaneous injection
Frequency 1-3 times daily
Duration 8-12 week course (unregulated use)

A modified, more stable fragment of GHRH, essentially the same active compound as CJC-1295 without DAC; not FDA-approved, sold only as a research chemical.

Where this comes from User-reported/research-chemical vendor literature; limited early pharmacology data

There is no approved human dosing for this compound. The figures above are what users and vendors report, not what has been established as safe or effective. Treat them as a record of what is done, not as guidance.