186 In the index

Pentosan polysulfate PPS

An FDA-approved oral medication (Elmiron) for a painful bladder condition. It works well for that approved use, but long-term use has been linked to a specific type of eye damage, leading to updated safety warnings.

Also known as Elmiron

Effects Heal

Routes Injectable Oral

Legal status Prescription drug

WADA Not listed

Reported dosing

Approved label

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 100 mg, 3 times daily

Reported range 100-300 mg/day

Route Oral

Frequency 3 times daily

Duration Chronic/ongoing (as prescribed)

FDA-approved (Elmiron) for interstitial cystitis; carries a boxed warning for retinal pigmentary changes with long-term use.

Where this comes from FDA prescribing information

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.