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Cycle support / Organ and cycle health

1 In the index

N-Acetylcysteine NAC

An FDA-approved emergency antidote for acetaminophen (Tylenol) overdose, and a well-studied antioxidant also used off-label for mental health conditions like OCD and addiction. Its antidote use is rock-solid; a growing number of human trials suggest it may modestly help as an add-on treatment for several mental health conditions.

Also known as N-acetyl-L-cysteine, acetylcysteine, mercapturic acid, Acetadote, L-Acetylcysteine, Fluimucetin, Respaire

Effects Heal
Routes Oral
Legal status Dietary supplement
WADA Not listed

3D Molecular Structure of C5H9NO3S

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  • Carbon
  • Hydrogen
  • Nitrogen
  • Oxygen
  • Sulfur

Chemistry

Formula
C5H9NO3S
Molar mass
163.20
CAS
616-91-1
PubChem CID
12035
IUPAC name
(2R)-2-acetamido-3-sulfanylpropanoic acid
InChIKey
PWKSKIMOESPYIA-BYPYZUCNSA-N

Reported dosing

Approved label

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 600 mg
Reported range 600-2400 mg/day
Route Oral (or IV in clinical overdose treatment)
Frequency 1-3 times daily
Duration Ongoing (supplement use) or single/short IV course (clinical antidote use)

Sold as a dietary supplement; also an FDA-approved IV/oral antidote for acetaminophen overdose (Acetadote/Mucomyst).

Where this comes from FDA prescribing information (antidote use); clinical trials and supplement-industry dosing (general use)

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.