Melatonin MEL

The body's own natural sleep hormone, sold over the counter in the U.S. Human studies support modest benefits for falling asleep and adjusting to time-zone changes like jet lag, with a strong overall safety record at typical doses.

Also known as N-acetyl-5-methoxytryptamine, Melatonine, Circadin, 5-Methoxy-N-acetyltryptamine, Melatol, Melovine, Melapure

Effects Longevity Sleep

Routes Oral Sublingual

Legal status Dietary supplement

WADA Not listed

3D Molecular Structure of C₁₃H₁₆N₂O₂

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Chemistry

Formula: C13H16N2O2
Molar mass: 232.28
CAS: 73-31-4
PubChem CID: 896
IUPAC name: N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide
InChIKey: DRLFMBDRBRZALE-UHFFFAOYSA-N

Reported dosing

Clinical data

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 1-5 mg

Reported range 0.5-10 mg, taken 30-60 minutes before bed

Route Oral

Frequency Once daily (at bedtime)

Duration Short-term or ongoing (supplement use)

Sold over-the-counter as a dietary supplement in the US; a prescription-only medication in some other countries.

Where this comes from Clinical trials; supplement-industry dosing

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.