27 In the index

Dexamethasone DEX

A powerful, FDA-approved anti-inflammatory steroid used for a wide range of conditions, and famously shown to reduce deaths in severe COVID-19. Extensive research supports its effectiveness, but long-term use carries well-known risks like bone thinning, high blood sugar, and weakened immunity.

Also known as Decadron, Aeroseb-Dex, Cortisumman, Calonat, Decaderm, Dexacortal, Dexacortin

Effects Heal

Routes Injectable Oral

Legal status Prescription drug

WADA Banned in-competition

3D Molecular Structure of C₂₂H₂₉FO₅

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Chemistry

Formula: C22H29FO5
Molar mass: 392.5
CAS: 50-02-2
PubChem CID: 5743
IUPAC name: (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
InChIKey: UREBDLICKHMUKA-CXSFZGCWSA-N

Reported dosing

Approved label

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 0.75-9 mg/day depending on indication

Reported range 0.5-40 mg/day, highly indication-dependent

Route Oral, IV, or IM

Frequency 1-4 times daily, or tapering courses

Duration Short courses (days) to chronic, depending on indication

FDA-approved corticosteroid; dosing must be individualized by a physician given the wide range of uses and tapering requirements.

Where this comes from FDA prescribing information

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.