23 In the index

Pregnenolone PREG

A natural hormone often called the 'mother hormone' because the body uses it to build several other hormones, including testosterone and cortisol, sold over the counter as a supplement. Human studies on mood and thinking are limited and show mixed results, without strong consistent proof of the benefits often claimed.

Also known as P5, 3beta-Hydroxypregn-5-en-20-one, Arthenolone, Regnosone, Skinostelon, Enelone, Natolone, Bina-Skin

Effects Focus Hormonal

Routes Oral

Legal status Dietary supplement

WADA Not listed

3D Molecular Structure of C₂₁H₃₂O₂

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Chemistry

Formula: C21H32O2
Molar mass: 316.5
CAS: 145-13-1
PubChem CID: 8955
IUPAC name: 1-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone
InChIKey: ORNBQBCIOKFOEO-QGVNFLHTSA-N

Reported dosing

Clinical data

What has been reported in the literature and by users. This is a record of what is done, not a recommendation.

Typical dose 10-50 mg/day

Reported range 10-500 mg/day (very high end used in some experimental protocols)

Route Oral

Frequency Once daily

Duration Ongoing (supplement use)

Sold as a dietary supplement in the US; not FDA-approved as a drug. High-dose use is not well studied for long-term safety.

Where this comes from Limited clinical trials; supplement-industry dosing

These figures are recorded for reference and are not a recommendation. Dosing is a decision for you and a clinician.