Polyphenols are micronutrients and phytochemicals that have antioxidant and anti-inflammatory properties. Polyphenol-based supplements are most commonly sourced from berries, herbs, and various spices and most contain a variety of broad-spectrum polyphenols that provide full-body support.
In this article, we’ll discuss what polyphenols are in further detail and review their major health benefits. Additionally, we’ll cover the best polyphenol supplements available.
What Are They and What Do Polyphenols Do?
- Polyphenols are compounds found naturally in foods that have antioxidant properties
- The most common forms of polyphenols are flavonoids and phenolic acids
- The top 3 foods with the highest concentration of polyphenols include cloves, dried peppermint, and star anise
- Polyphenols defend the body from free radical damage, boost the immune system, aid digestion, and improve energy
Comparison of the 4 Best Polyphenol Supplements
Green Tea Extract
Resveratrol Rapid + by Nuzena
Best Polyphenol Supplements
Best Polyphenol Blend – Resveratrol Rapid + by Nuzena
Resveratrol Rapid + was specifically designed by health professionals to provide customers with natural antioxidant and anti-inflammatory support.
Not only does this product provide an immune system boost, but it also helps lower blood pressure and aid the management of blood sugar levels.
Studies have displayed resveratrol’s effectiveness in increasing the lifespan of certain organisms as well as increasing nitric oxide which leads to a blood-pressure-lowering effect.
It is recommended for adults to take 2 capsules daily of this product. Each daily serving of Resveratrol Rapid + contains 2400 mg of 50% trans-resveratrol complex.
Best Elderberry Supplement – Elderberry Gummies by Essential Elements
This 4-in-1 formula contains the major immune-boosting ingredients of Sambucus nigra (Black Elderberries), Vitamin C, Echinacea purpurea, and Propolis.
Elderberries are one of the top 10 natural sources of antioxidants and contain the following major flavonoids: anthocyanins C3G, cyanidin-3-o-sambubioside (C3S), hyperoside, isoquercetin, quercetin
A systematic review of multiple human trials has shown that elderberries might reduce symptoms of respiratory infections.  Additionally, a randomized controlled trial with 312 participants also suggested that the extract of the elderberry fruit reduced the severity and duration of a cold significantly more than placebo. 
It is recommended to take 2 gummies per day.
Best Custom Polyphenol Supplement – Persona
Persona Nutrition provides each of its customers with their own personalized, monthly subscription vitamin pack to best meet their specific health needs.
In order to best customize individual vitamin packs, customers should initially complete a quick assessment on Persona’s website to receive personalized, science-backed supplement recommendations.
Specific questions on this assessment gather information on specific types of diets, allergies and food sensitives, health conditions, medication use, and more.
Alternatively, customers may also use the option to filter vitamins by certain health needs on the products page. Ingredients offered by Persona that contain polyphenols include:
- Fermented Ginseng
- Ginger Extract
- Ginkgo Biloba Extract
- Green Tea Extract
- Olive Leaf
- Peppermint Plus
- Quercetin Plus
- Vitamin C with Bioflavonoids
All vitamins and supplements offered by Persona adhere to FDA certified Good Manufacturing Practices and several of the ingredients included within its vitamin packs are trademarked, providing customers with greater transparency and trust.
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Best Green Tea Extract
– Green Tea Extract by Bulk Supplements
Green Tea Extract by BulkSupplements is one of the most powerful antioxidant supplements offered by the company and is known for providing a wide range of health benefits. Some of the major benefits of taking green tea extract include a reduction in inflammation, a natural increase in energy, accelerated fat loss, improved cognition, and healthier skin.
This product contains 500 milligrams of green tea leaf extract per serving which is standardized to contain 50% polyphenols, 35% catechins, and 15% EGCG. Additionally, Green Tea Extract is free of sugar, soy, dairy, yeast, gluten, and corn and contains no other ingredients.
This product comes in pure powder form and is sold in quantities ranging from 100 grams to 25 kilograms. Adults should take 500 milligrams once or twice daily or as directed by a physician.
BulkSupplements offers over 500 supplements which fall under categories such as fitness and sports, heart health, brain and memory, weight management, and immune support. All of its products contain pure raw ingredients, are lab tested for purity, and are manufactured at a facility that is FDA inspected. BulkSupplements stands out among its competitors due to its product versatility and ability to serve customers who stem from diverse health backgrounds, lifestyle choices, and dietary preferences.
Types of Polyphenols
There are over 8,000 different polyphenols found in food. Nearly 60% of polyphenols are classified as flavonoids and around 30% are classified as phenolic acids
Flavonoids can be further split into flavonols, flavones, flavanones, flavanols, anthocyanins, and isoflavones. This type of polyphenol can be found in foods such as onions, tea, wine, citrus fruits, aromatic herbs, chocolate, and some soybean-derived products.
Phenolic acids can be split into 2 subclasses of benzoic acid and cinnamic acid. This type of polyphenol is generally found in foods including fruits, vegetables, seeds, and whole grains.
Polyphenol Rich Foods
The European Journal of Clinical Nutrition (EJCN) conducted a study to find which foods and food groups contained the highest concentration of polyphenols. Over 452 foods were analyzed from the Phenol-Explorer database and it was found that the following 10 food sources contained the highest overall concentration of polyphenols:
- Peppermint, dried
- Star anise
- Cocoa powder
- Mexican oregano, dried
- Celery seed
- Black chokeberry
- Dark chocolate
- Flaxseed meal
- Black elderberry
Additionally, the data analysis showed that the 5 food groups containing the most food items with the highest polyphenol content were seasonings, fruits, seeds, vegetables, and non-alcoholic beverages.
Polyphenol supplements usually provide either a variety of broad-spectrum polyphenols sourced from superfoods, berries and herbs or contain high-purity, high-potency extracts. The best polyphenol supplements include ingredients sourced from resveratrol-containing foods, elderberries, bilberries, cranberries, green tea extract, quercetin, turmeric, bitter orange, and chokeberries.
When selecting a polyphenols supplement you should make sure to choose a product that has anti-inflammatory properties and combats free radical damage through the use of potent antioxidants.
The main health benefits of polyphenols include shielding the body from the toxic effects of free radicals, enhancing homeostasis, and preventing disease.
Some sources of polyphenols may also serve as prebiotics which boost the ratio of useful bacteria in the gut. This in turn aids blood sugar and weight management as well as reduces the risk of forming certain chronic diseases.
Polyphenols for Skin
Polyphenols for Weight Loss
What’s the Verdict on Polyphenols?
All of the above supplements provide immune-boosting and anti-aging benefits. Although some of the components of these supplements can be obtained from superfoods, the overall availability of these components within supplements is much higher and provides a wider realm of health benefits.
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