Best CoQ10 Ubiquinol Supplements

Your body’s natural levels of CoQ10 (Ubiquinol) steadily decrease after the age of 40. Along with aging, reduced assimilation and statin drugs also contribute to CoQ10 deficiency.

CoQ10 is a coenzyme that provide energy to the cells and it also serves as an antioxidant to protect cells from free radical damage. It’s best known for enhancing the immune system and well as improving brain and heart health.

In this article, we will review the 4 best CoQ10 supplements and highlight each product’s key features and main health benefits.

Comparison of the 4 Best CoQ10 Ubiquinol Supplements

Best for Purity (Amazon)
Coenzyme Q10
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Best CoQ10 Ubiquinol SupplementsBest CoQ10 Ubiquinol SupplementsBest CoQ10 Ubiquinol SupplementsBest CoQ10 Ubiquinol SupplementsBest CoQ10 Ubiquinol Supplements
Best for Purity (Amazon)
Coenzyme Q10

Coenzyme Q10 (CoQ10) comes in pure powder form and in softgels. Adults should take 50 mg to 200 mg or 1 softgel daily.

Ubiquinone
50-200mg
No Other Ingredients
Powder or Capsule
$0.17-0.63/Serving

Best Ubiquinol
Persona
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Best CoQ10 Ubiquinol SupplementsBest CoQ10 Ubiquinol SupplementsBest CoQ10 Ubiquinol SupplementsBest CoQ10 Ubiquinol SupplementsBest CoQ10 Ubiquinol Supplements
Best Ubiquinol
Persona

This multivitamin pack is custom-tailored to each customer's unique health needs through the use of a highly-detailed online questionnaire.

5 Min Assessment
Daily Packs
Approved by Doctors
Live Support
Mobile App

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Best Ubiquinone
CoQ10 Complex +
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Best Ubiquinone
CoQ10 Complex +

This CoQ10 formula contains 200mg of pure Ubiquinone that supports heart health, regulates blood pressure, and may alleviate migraine-associated pain.

Ubiquinone
200mg
No Other Ingredients
Capsule
$1.17/Serving

Best for Energy
Energy
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Best for Energy
Energy

Energy is composed of MicroActive® Q10, BioPerine®, BioPQQ® and Bio-Enhanced® nutrition technology which work together to provide you with the ultimate non-stimulant boost.

MicroActive® Q10
100mg
+ Energy Supplements
Capsule
$1.63/Serving

Best CoQ10 Brand: BulkSupplements (Amazon)

Best CoQ10

Coenzyme Q10 (CoQ10) by BulkSupplements provides an extensive amount of health benefits which include improvements in joint and muscular health, weight management, oral health, lung health, sexual health, skin health, cardiovascular health, and improved immune function. This product is free of sugar, soy, dairy, yeast, and gluten and contains CoQ10 in its purest form.

Coenzyme Q10 (CoQ10) comes in pure powder form and in softgels. The pure powder form is sold in quantities ranging from 10 grams to 25 kilograms whereas the softgels are sold in counts of 100 or 300. Adults should take 50 mg to 200 mg or 1 softgel daily.

BulkSupplements offers over 500 supplements which fall under categories such as fitness and sports, heart health, brain and memory, weight management, and immune support. All of its products contain pure raw ingredients, are lab tested for purity, and are manufactured at a facility that is FDA inspected. BulkSupplements stands out among its competitors due to its product versatility and ability to serve customers who stem from diverse health backgrounds, lifestyle choices, and dietary preferences.

Pros
  • Free of additives

  • CoQ10 in pure form

  • Available in powder and softgel form

Cons
  • Only sold on direct website

  • Restricted in some countries

  • Hard to properly dose with softgels

Best Custom Pack with Ubiquinol – Persona

best personalized vitamin pack

Persona Nutrition offers daily vitamin packs that are 100% personalized and designed to meet the specific health needs of each and every customer.

The company offers both prenatal vitamin packs as well as individual ingredients that can be used towards building the ultimate fertility supplement stack.

Customers have the option to complete a quick assessment on Persona’s website to determine which vitamins, minerals, and supplements would be best for their health goals or they may individually pick out the ingredients they want to include in their vitamin packs.

Persona just so happens to offer an add-in option for the optimal form of CoQ10!

Ubiquinol contains 100 mg of bioavailable CoQ10 that’s used directly towards promoting heart health, improving cellular energy, and reducing cellular damage caused by inflammation.

Pros
  • Highly Detailed Online Assessment

  • Live Nutritionist Support

  • 80 Different Ingredients Available

Cons
  • Not All Ingredients are Trademarked

  • Uses Proprietary Blends

  • Does Not Rely on Blood Test or DNA Test

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Best CoQ10 – CoQ10 Complex + by Nuzena

Best CoQ10 Supplements

CoQ10 Complex + by Nuzena provides superior antioxidant support that has been clinically proven to supply your body with extra energy and all-around cellular support.

This pure ubiquinone supplement is ideal for anyone affected by the following health issues:

  • Lack of energy
  • Chronic fatigue or exhaustion
  • Brain fog or inability to concentrate
  • High blood pressure
  • Cardiovascular-related health concerns
  • Frequent migraines or eye strain
  • Issues with fertility
  • Pain associated with inflammation

Nuzena only uses ingredients that are verified by scientific research conducted by health professionals and its products are highly recommended by major health institutions, such as Mayo Clinic, Harvard Medical School, and NDNR. 

It is highly recommended for all adults, especially those who are above the age of 40 or who suffer from heart conditions, to take a CoQ10 supplement since the aging process diminishes our natural levels overtime. Additionally, most people do not consume enough CoQ10 through food alone, and those who follow a plant-based diet risk having even lower levels than the average person since it is naturally found in meat and fish.

Each serving of CoQ10 Complex + contains 200mg of Ubiquinone and adults should take one capsule per day, preferably within 30 minutes prior to eating or as directed by a healthcare professional.

Although this formula is not intended to cure or prevent diagnosed medical conditions, it is strongly believed that the use of this supplement might help treat and manage certain heart conditions, migraines, and Parkinson’s disease.

Pros
  • Made with 100% natural ingredients

  • Contains 200mg of Ubiquinone

  • Clinically proved ingredients

Cons
  • Only contains 1 ingredient 

  • Some people may require a higher or lower dose

  • Capsule form prevents dose reduction

Best Energy Supplement – Performance Lab® Energy

Best CoQ10 Ubiquinol Supplements

Energy by Performance Lab is designed to provide superior mitochondrial support for cell energy and vitality. Whether you’re looking to improve your overall energy or boost your athletic performance Performance Lab® Energy can help.

Performance Lab® Energy sets itself apart from other energy supplements through not relying on caffeine for creating an energy boost. Rather, Energy is composed of MicroActive® Q10, BioPerine®, BioPQQ® and Bio-Enhanced® nutrition technology which work together to provide you with the ultimate non-stimulant boost. 

Energy is prebiotic-infused and comes in 100% plant-based NutriCaps®. This supplement is vegan friendly and also free of additives and allergens. 

About Performance Lab 

Performance Lab offers a wide variety of training and nutritional supplements which aid human performance and promote all-around health.  Its supplements provide support for better sleep, vision, cognition, and energy as well as enhance muscle growth, strength, endurance, and training intensity.

Performance Lab uses premier nutrition technologies in order to revolutionize healthy performance nutrition as well as to provide the highest quality performance supplements available on the market. This company provides one of the world’s most sophisticated nutritional supplement systems for optimizing daily performance and long-range health.

Best CoQ10 Ubiquinol Supplements

Unique Features

No Caffeine 

Unlike most energy supplements, Performance Lab Energy uses nutrition technology over caffeine to provide a natural boost.

Bioavailability-Enhanced MicroActive® Q10

In most cases, CoQ10 is difficult for the body to absorb. In order to aid absorption, Performance Lab® Energy uses bioavailability-enhanced MicroActive® Q10 which absorbs faster and releases slowly to provide sustained cell energy support.

PPQ is More Powerful than Vitamin C

Performance Lab® Energy BioPQQ® works together with CoQ10 to promote immunity by aiding mitochondria all throughout the body within almost all cells. It’s also an antioxidant related to B-vitamins which possesses nearly 5,000 times the antioxidant power of Vitamin C.

ALCAR Provides Dual-Powered Support

Acetyl-L-Carnitine (ALCAR) works as an athletic performance-enhancer by preserving energy in muscle while promoting the use fat for energy. This leads to optimal body composition overtime through losing body fat and gaining muscle.

BioPerine® is Highly Purified Black Pepper Extract

BioPerine® is standardized to supply 95% piperine which is much purer than competing piperine products.

Pros
  • Stimulant-free energy

  • No additives or allergens

  • 100% plant-based

Cons
  • Expensive- $49/box

  • Only 30 servings

  • Only available on the brand official website

 

 

Ubiquinol CoQ10

The following are the major health benefits that are associated with taking CoQ10 (Ubquinol):

  • Improves cardiovascular health
  • Lowers high cholesterol
  • Increases natural levels of CoQ10
  • Helps maintain healthy blood sugar levels
  • Boosts cellular energy
  • Enhances cognitive function
  • Reduces joint pain and inflammation

Ubiquinol vs Ubiquinone

There are two forms of Coenzyme Q10: ubiquinol and ubiquinone. Both are true forms of CoQ10, however, they are not the same in nature. [1]

Ubiquinone is not very absorbable on its own, due to it being fat-soluble, and is generally combined with emulsifiers in most ubiquinone-based CoQ10 supplements. In contrast, ubiquinol is water-soluble and is up to eight times more absorbable than ubiquinone. [2]

What is the Best Form of CoQ10?

Due to its superior absorption and high quality, ubiquinol is considered to be the best form of Coenzyme Q10. However, supplements that contain ubiquinol tend to be more expensive and more difficult to find when compared to those that contain ubiquinone.

Thus, ubiquinol is the best overall form of CoQ10 but those who are looking for a cheaper option that’s more widely available may want to choose a ubiquinone-based CoQ10 supplement instead.

Ubiquinol with Shilajit

Although ubiquinol is highly potent on its own, it’s even more effective and has far greater health benefits when combined with shilajit.

Shilajit is a biomass that contains key nutrients that help increase energy and boost CoQ10 efficiency. [3] Shilajit is combined with CoQ10 in ubiquinol-based CoQ10 supplements in order to enhance overall mitochondrial health, which leads to better aging and reduction of disease. [4]

Best CoQ10 for Fertility

CoQ10 is used by women to improve fertility, especially those who are older or who have experienced complications with fertility in the past. As women age, their CoQ10 levels decrease and CoQ10 is absolutely essential for egg maturation and overall egg quality. [5]

Thus, in order to increase their chances of conceiving and having a healthy pregnancy, women who have struggled with fertility should supplement with CoQ10 in order to have the best egg quality possible.

Due to the enhanced absorbability and effectiveness of ubiquinol compared to ubiquinone, it is recommended for women to use ubiquinol for increasing their fertility over ubiquinone, if possible.

 

Take-Home Message

CoQ10 is very beneficial to your body and above all, it boosts your heart’s health. Purchasing the right one is very essential to get the health benefit you require.

References

See all references
[1] García-Corzo L, Luna-Sánchez M, Doerrier C, Ortiz F, Escames G, Acuña-Castroviejo D, López LC. Ubiquinol-10 ameliorates mitochondrial encephalopathy associated with CoQ deficiency. Biochim Biophys Acta. 2014 Jul;1842(7):893-901. doi: 10.1016/j.bbadis.2014.02.008. Epub 2014 Feb 24. PMID: 24576561.

[2] Langsjoen PH, Langsjoen AM. Supplemental ubiquinol in patients with advanced congestive heart failure. Biofactors. 2008;32(1-4):119-28. doi: 10.1002/biof.5520320114. PMID: 19096107.

[3] Bhattacharyya S, Pal D, Gupta AK, et al. Beneficial effect of processed shilajit on swimming exercise induced impaired energy status of mice. Pharmacologyonline. 2009;1:817-25.

[4] Bhattacharyya S, Pal D, Banerjee D. Shilajit dibenzo—pyrones: mitochondria targeted antioxidants. Pharmacology online. 2009;2:690-8.

[5] Miles MV, Horn PS, Tang PH, Morrison JA, Miles L, DeGrauw T, Pesce AJ. Age-related changes in plasma coenzyme Q10 concentrations and redox state in apparently healthy children and adults. Clin Chim Acta. 2004 Sep;347(1-2):139-44. doi: 10.1016/j.cccn.2004.04.003. PMID: 15313151.

Kathryn Giuffrida MPH

Kathryn obtained a MPH in Toxicology & Risk Assessment from the University of South Florida in 2018. She's also a year-round swimmer who qualified to compete in the 2020 TYR Pro Series.

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