Best Research Peptides

Peptides are rising in popularity in the fitness and recreational world. Hard to understand them, and even harder to know which ones are the best research peptides.
Medically reviewed by Dr. Mohammed Fouda
Dr. Fouda uses his extensive knowledge and expertise as an academic scholar to medically review articles for scientific accuracy and credibility, ensuring that the medical information presented is up-to-date and trustworthy. He is responsible for ensuring the quality of the medical information presented on our website.

Type in “peptides” into Google and you might be met with some Collagen peptides or even some Creatine. Not exactly what you were looking for, right? I know your dirty little mind is looking for something a little stronger, a little more experimental…

Research chemicals have been a compound type that has increased dramatically in the fitness world, and for good reason. With the increase in accessibility to pure Peptides, people are noticing that these compounds can have a massive impact.

Increase in muscle growth, fat loss, and even life quality! Peptide suppliers have taken notice and created a spread of new Peptides online, but which ones are best?

Which research Peptides are worth your time, and which ones deserve a one-star review? While you Google how to measure an IU, I’ll find the Best Research Peptides.

Warning: The content on Muscleandbrawn.com and the information included in this article is intended for entertainment and informational purposes only. It is not intended nor implied to be a substitute for professional medical advice. Prior to buying anything, check that it is compliant where you live with your current government laws. We frequently mention research chemicals that are not made for human consumption. Therefore, before purchasing any product for personal use, consult with your doctor or healthcare provider first.

What are Research Peptides?

If you’re already aware of how Peptides differ from normal Collagen and Creatine Peptides, move right along.

Okay, you stuck around! Peptides are simply Amino Acids (the building blocks of Proteins) that are bound with peptide bonds – hence the name. These Peptide chains will have a specific effect on the human body, based on the sequence of Amino Acids.

Human Growth Hormone Fragment will have a strong lipolysis effect on the human body [1], whereas something like Body Protection Compound 157 will have a strong angiogenesis effect [2]. Both are Peptides, however, they have wildly different effects.

The most popular Peptides include Human Growth Hormone, BPC 157, IGF-1 (Insulin-like Growth Factor 1), and Growth Hormone Secretagogues. Peptides have been found to have a massive amount of benefits such as:

  • Increase in Lean Muscle Mass [3]
  • Decrease in Adipose Tissue [1]
  • Improved Sexual function [4]
  • Improved Recovery from injury [2]
  • Anti Aging effects [5]
Best Research Peptides
Figure 1: The health and physiological implications of increased IGF-1

There is one thing to remember, a lot of these Peptides are still classified as research chemicals, and they have not been approved for human consumption due to a lack of scientific research. In time they might, but for now, you cannot purchase Peptides (certain ones) unless they are classified as research chemicals.

What are the Best Research Peptides?

When trying to look for the “best” of anything, there are a great number of variables you need to take into account. What is the best Peptide to some, might not be the best to others.

Yes, we all have muscle cells that should react the same, however, we know that in reality there are going to be certain Peptides that react amazingly to some, and quite poor to others. Sometimes you have highly purified Peptides, and you still don’t have a great reaction – it happens.

Taking that into account, the best Research Peptides would have to be HGH Fragment, IGF DES, HCG, Melanotan II, and CJC 1295.

These are all going to be used for specific reasons, and you can easily buy these research liquids online – let’s take a deeper look at these.

Best Fat Loss Peptides

HGH Fragment 176-191 (AOD 9604)

Fat loss or Beta Oxidation is the process in which the body will use Free Fatty Acids and break them down to produce energy. The development of therapeutic compounds to increase this process is ever going, as obesity rates are higher than ever.

One of the newer treatment ideas has been tested in vitro research, HGH Fragment. This is a fragment of the whole HGH Peptide, and this part is ideal for the act of lipolysis.

It will lead to increased lipase levels in the body, which will lead to increased fat being released into the blood from your fat cells [1]. More fat in the blood means you can use that fat more effectively as fuel when living/training.

Clinical studies have found Frag to be quite effective at helping individuals lose fat. Pair this with a good resistance training program and diet, and youโ€™re bound to shed a few pounds

HGH Frag Overview

โญ๏ธ Top Benefits:
Increases natural HGH production
Promotes weight loss
Enhances fat metabolism
May aid in muscle mass preservation during weight loss
๐Ÿงช Form: Injectable liquid
โŒ›๏ธ Max Time Used: 14 weeks
๐Ÿ’ฐ Average Cost: $50
โค๏ธโ€๐Ÿฉน Side Effects:
Potential insulin resistance
Possible injection site reactions
May experience headaches
Potential for joint pain
โ˜ข๏ธ Dangers:
Limited long-term safety data available
Potential for abuse or misuse
Not approved by the FDA for weight loss
Possible unknown long-term risks
๐Ÿ“š Best Peptide Stack: GHRP/HGH/IGF-1
โšค Men/Women: Suitable for both men and women
โžก๏ธ Go to the Full review

  • Does not cause Insulin resistance as pure HGH does
  • Has the potential to cause spot-reducing fat loss
  • Does cause some Insulin resistance

IGF-1

IGF 1 refers toย Insulin-Like Growth Factor,ย a natural hormone found in the body working in close relation to natural Growth Hormone production.

IGF 1 will virtually act on all of the bodyโ€™s cells, looking at what it can do in muscle cells, it will boost protein synthesis, it might act as a glucose uptake aid, and it will also lead to a positive Nitrogen balance.

All of these form part of theย perfect muscle-building environment,ย and thus IGF 1 LR3 can help with this when combined with training, diet, and the correct polypharmacology.

Another thing to consider is the fact that it could play a role in the downregulation of Glucocorticoids. This will not only massively reduce inflammation but thereby also boost recovery tremendously.

IGF-1 Overview

โญ๏ธ Top Benefits: Anti-aging, improved muscle mass, fat loss, and improved life quality
๐Ÿงช Form:ย Injectable liquid
โŒ›๏ธ Max Time Used: 2 – 3 Weeks
๐Ÿ’ฐ Average Cost: $88.99
โค๏ธโ€๐Ÿฉน Side Effects: Hypoglycemia and stomach discomfort
โ˜ข๏ธ Dangers: Hypoglycemia can be dangerous if unexpected
๐Ÿ“š Best Peptide Stack: HGH
โšค Men/Women: Men and women
โžก๏ธ Go to the Full review

  • Anti-aging
  • Muscle gain
  • Fat loss
  • Improved life quality
  • Better hair and skin
  • Hypoglycemia
  • Stomach discomfort
Best Peptide for Low Testosterone

HCG

Low Testosterone or Hypogonadism is the term used to describe a male that does not produce enough Testosterone, below around 300 nanograms per deciliter (ng/dL). This can be due to drug use, age, or even injury.

Quality Peptides can actually help you with this problem! In a process of trying to restart the production of Testosterone, Peptides will either act like the hormones that lead to the release of Testosterone, or even cause an increase of those hormones.

HCG or human chorionic gonadotropin is the most common of these, and it has actually been approved for human use. HCG will lead to an increase in Luteinizing hormone in the body, which in turn, will cause an increase in Testosterone production.

HCG often gets grouped with other cosmetic Peptides, when in reality, no research has ever found it to be good for fat loss. HCG can increase Testosterone levels by up to 50% [6].

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  • Increases Testosterone levels
  • Increases Sperm levels
  • Can lead to an increase in Estrogen as well, so a SERM might be needed
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Best Peptide for Libido

Melanotan II

Sexual function of most men begin to dwindle past the age of 30. This is also the time when most men begin to carry a bit of extra weight.

Amazingly enough, you can kill two birds with one stone with the Peptide known as Melanotan II. Yes, the Peptide that makes you very tan.

Melanotan is known to help with sexual function (increases libido) by being an agonist for penile tissue, and being a somewhat effective treatment for erectile dysfunction.

Melanotan is also known to have a negative effect on hunger, which in turn can actually lead to the person eating less, meaning weight loss. This is still a Peptide that needs to be researched, and as the Peptide sciences increase, this might be more common in the ED treatment world.

Melanotan II Overview

โญ๏ธ Top Benefits:ย Skin tanning, Energy homeostasis, Treats ED
๐Ÿงช Form:ย Injectable peptides, Nasal sprays
๐Ÿ’‰ Typical Dosage:ย 0.1 mg to 1 mg
โŒ›๏ธ Typical cycle duration:ย Variable
๐Ÿ’ฐ Average Cost:ย $41
โœ… Availability:ย Easily available
โค๏ธโ€๐Ÿฉน Side Effects and Dangers:ย Spontaneous erections, systemic toxicity
๐Ÿ“š Best Peptide Stack:ย Melanotan 1 / Melanotan 2
โžก๏ธ Go to the Full review

  • Darkening of skin
  • Fat Loss
  • Improved libido
  • Kidney damage
  • Diarrhea
  • Priapism
#1 Best Overall

CJC 1295 + Ipamorelin Stack

This is the quintessential combination for Growth Hormone secretion. CJC-1295 is a Growth Hormone Releasing Hormone while Ipamorelin is one of the Growth Hormone Releasing Peptides.

Some studies are showing that using a GHRH and GHRP together will yield better results [2].

As this will massively increase your endogenous Growth Hormone release, you can expect similar results to taking pure HGH. Benefits include weight loss, muscle growth, and better body composition, and various human studies found that people just feel better on HGH therapy.

This is a very common peptide stack and is going to result in a better life, and potentially, your desired physique.

Stack Overview

โญ๏ธ Top Benefits: Increase in Lean Muscle Mass, Enhanced Endurance, Improved Fat Loss, Better Sleep Quality, Enhanced Recovery, Strengthening of Joints and Connective Tissue.
๐Ÿงช Form: Injectable.
๐Ÿ’‰ Typical Dosage: CJC-1295: 1000 mcg to 2000 mcg per week; Ipamorelin: 200 mcg to 300 mcg per day.
โŒ›๏ธ Typical Cycle Duration: 8 to 12 weeks (60 to 90 days).
๐Ÿ’ฐ Average Cost: Approximately $49 (Prices may vary depending on the supplier and product concentration).
โœ… Availability: Easily available through various online peptide suppliers, but a prescription may be required in some regions.
โค๏ธโ€๐Ÿฉน Side Effects and Dangers: Vertigo, Increased Body Temperature, Water Retention, Headaches, Injection Site Reactions, Increased Hunger, Lowered Blood Sugar Levels.
๐Ÿ”„ See before and after
โžก๏ธ Go to the Full review

Best Research Peptides for Bodybuilding?

When it comes to bodybuilding, these guys are looking for the best of the best, only premium Peptides will do. So, which Peptides are they going to be looking at using? Well, because bodybuilders are so singular in their goals, which Peptides are going to be better for which purposes:

1) Best Peptides for Muscle Gain: It depends on what else is in your cycle, and what you need from the Peptides. So, before you buy Peptides, identify what you need. If you need fullness and size, you might look at IGF-1 DES. If you’re looking for the strength associated with muscle gain, you could benefit from BPC-157, as it will improve recovery, meaning you will be able to get stronger a lot easier. For the most part, IGF-1 DES is your best bet.

2) Best Peptide for Fat Loss: This is a tie between actual HGH and HGH Fragment. Finding HGH Peptides online is hard and illegal, HGH Frag is a lot easier. They will do a lot less for muscle gain than other Peptides, but they are amazing for weight loss.

3) Best Peptide for Recovery: Again, another tie between TB 500 and BPC-157. Both are excellent for recovery and are highly used in clinical trials for research purposes.

Best Source for Research Peptides?

You have two routes to take when it comes to Peptides. The first is using a vendor or one of the Peptide companies such as Amino Asylum, or you can use an online Peptide clinic.

A Peptides shop will have a greater range of products, and they will make buying Peptides online slightly easier. That said, Peptide clinics are going to offer you testing and health management with doctors and other health professionals.

Using a clinic offers you the best quality Peptides available seeing as it is Pharma grade. They will always provide excellent customer service, and you get to monitor your health meaning there are almost zero chances of developing side effects.

๐Ÿ’‰Become a Peptide Expert (Protect your Health) ๐Ÿ’‰

Take our FREE 25-email course to learn everything you need to know about the scientific application of peptides. Discover how to protect your health, avoid sketchy peptide vendors, and stop wasting your hard-earned money. ๐Ÿ”ฅ ๐Ÿงช ๐Ÿ’Š ๐Ÿ’ช ๐Ÿ’‰ ๐Ÿฉธ๐Ÿฅ ๐ŸฅŽ

USA Research peptides

The USA is a place where you can find a lot of Peptides for sale. There are plenty of great vendors online such as Amino Asylum or Sports Technology Labs, but you can also consider an HRT Clinic. They might have slightly different Peptides from one another.

An HRT clinic will be focused on the health benefits of Peptides, such as cognitive function, weight loss, and sexual health improvements.

Peptide companies on the other hand would usually stock anything that the market might need – muscle building Peptides specifically. Both will have quality products, however, and have to go through high-performance liquid chromatography to produce their powder-form Peptides.

It would be wise to look at online reviews to establish which company is best for your needs and that you do not get the wrong product.

How do Peptides Cause Muscle Growth?

Peptides can cause muscle growth. There is a big misconception that Peptides will not cause any muscle growth when in reality, there is in vitro research showing that muscle cells do react to Peptides.

That said, muscle cells will react a lot better to Anabolic Steroids and SARMs compared to Peptides. All of these are artificially created, however, the Steroids and SARMs are just a lot more anabolic and will cause the growth of contractile proteins a lot better, and a lot faster.

Peptides can cause muscle growth usually by increasing the amount of IGF-1 in the body, which is argued to cause the growth of Satellite Cells. This mechanism is apparently what causes people to unlock new levels of muscularity, especially if they are using other compounds as well. So, while it is undeniable that certain Peptides can be used for adipose loss or wound healing, you would need to work pretty hard to see big muscle mass increases from Peptides.

How do Peptides Cause Fat Loss?

Most people buy research Peptides simply to burn fat. There is nothing wrong with this, as there are a host of Peptides that can help you with this. Here is how Peptides can cause fat loss:

  1. Growth Hormone forces the Pancreas to release a great amount of Lipase
  2. Free Fatty Acids (FFA) are liberated from Adipocytes via Lipase 
  3. FFA are transported by the blood to different parts of the body
  4. FFA can then enter metabolizing tissue/cells (Cells with Mitochondria, except for Central Nervous Tissue 
  5. Long-chain-fatty-acidโ€”CoA ligase (Enzyme of the Ligase Family) is the catalyst of the reaction of FFA with ATP 
  6. This reaction forms AMP and inorganic pyrophosphate and gives off fatty acyl-adenylate
  7. Fatty acyl-adenylate reacts with coenzyme A to give off a fatty acyl-CoA molecule
  8. The Carnitine shuffle is used for the acyl-CoA to enter the mitochondrion 
  9. Beta Oxidation then takes the FFA (acyl-CoA molecule at this point) and cuts it into two carbon chains 
  10. These carbon chains combine with co-enzyme A to form acetyl CoA
  11. Acetyl CoA condenses with oxaloacetate to form citrate

Then, finally, Acetyl CoA is dissipated and CO2 and H2O are released, as well as energy captured in the form of ATP.

What is the Best Research Company for Peptides?

When it comes to Peptides, you will want a source that is both reputable, cost-effective, has good shipping costs, secure shipping, and a lot of featured products. For these variables, the best research company for Peptides is Amino Asylum.

Research Peptides HCG?

HCG or human chorionic gonadotropin is a Peptide that is used to treat hypogonadism or low Testosterone in men and can be found for sale online. This is the best Peptide for hypogonadism treatment and can increase Testosterone by 50% [6].

Collagen Research Peptides?

Collagen is a Peptide, yes, but it is not a research Peptide. Collagen has been shown to help with bone and cartilage tissue, however.

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1) https://pubmed.ncbi.nlm.nih.gov/11713213/
2) https://pubmed.ncbi.nlm.nih.gov/27847966/
3) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1071449/
4) https://pubmed.ncbi.nlm.nih.gov/26194072/
5) https://pubmed.ncbi.nlm.nih.gov/29756419/
6) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6844348/

Contributors

Daniel Louwrens BSc PT

Daniel Louwrens BSc PT | Writer

Daniel Louwrens is a well-rounded fitness professional with over 10 years of experience in bodybuilding and fitness. He holds a BSc in Chemistry from the University of Western Cape and is a certified International Personal Trainer and Nutritionist. He is also a skilled bodybuilder and head coach for Muscle and Brawn. With his knowledge and expertise, he provides personalized training, nutrition, and recovery guidance to help clients reach their fitness goals.

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Dr. Mohammed Fouda

Dr. Mohammed Fouda | Reviewer

Dr. Fouda uses his extensive knowledge and expertise as an academic scholar to medically review articles for scientific accuracy and credibility, ensuring that the medical information presented is up-to-date and trustworthy. He is responsible for ensuring the quality of the medical information presented on our website.

Read all articles
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Dan Turner
Dan Turner
1 year ago

I have been reading up on peptides and it sounds like TB-500 & BPC-157 would be good.
I am looking for more strength, healing, and size. Would I need any kind of post cycle supplements after taking these two peptides?

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