Muscle and Brawn Forums
 

Go Back   Muscle and Brawn Forums > Supplements, Nutrition & Diet > Nutrition, Diet and Supplements

Notices

Nutrition, Diet and Supplements Discuss nutrition, diet, cutting and weight loss. Supplement discussions as well.

Reply
 
Thread Tools Search this Thread Display Modes
Old 11-12-2010, 06:03 PM   #1
Right Hook
Member
Brawn
Points: 1,765, Level: 24 Points: 1,765, Level: 24 Points: 1,765, Level: 24
Activity: 0% Activity: 0% Activity: 0%
 

Join Date: Aug 2010
Posts: 71
Reputation: 1864
Right Hook has made some good postsRight Hook has made some good postsRight Hook has made some good postsRight Hook has made some good postsRight Hook has made some good postsRight Hook has made some good postsRight Hook has made some good postsRight Hook has made some good postsRight Hook has made some good postsRight Hook has made some good postsRight Hook has made some good posts
Default L-arginine regulates fat loss

From a blog I read:



Amino Acid Controls Gene Expression in Muscle and Fat Tissue

I have always liked Arginine for a couple of reasons.

1. More Muscle Pump which just feels awesome, even if thereís no long-term benefit of it

2. Improved blood sugar.

3. Increased blood flow to the extremities which is good for romance and for people with cold hands.

4. Has a mild mood-mellowing effect.

But Iíve fallen in love with Arginine all over again since Iíve been reading so much about how long-term supplementation can affect genetic signals to build fat and burn muscle. The results wonít be mind-blowing by any stretch of the imagination, at least not as powerful as something like anabolic steroids or growth hormone (although Arginine does a good job of increasing GH output by inhibiting itís counterpart, Somatostatin) but the results, over the long term with a consistent training regimen and a decent diet, should yield some really solid results.

For those of us whose goal is to transform our bodies, not just lose fat but to redefine our physiques, Arginine is just what the doctor ordered.

And it looks like scientists have started uncovering the specific method that Arginine effects our body composition. It appears to increase the release of fat from fat cells (lipolysis) while at the same time encouraging lipogenesis (creation of new fat stores) in muscle Ė which isnít a bad thing necessarily unless oneís diet is completely out of whack.

__________________________

J Nutr Biochem. 2010 Jul 7. [Epub ahead of print]

Dietary l-arginine supplementation differentially regulates expression of lipid-metabolic genes in porcine adipose tissue and skeletal muscle.

Tan B, Yin Y, Liu Z, Tang W, Xu H, Kong X, Li X, Yao K, Gu W, Smith SB, Wu G.

Laboratory of Animal Nutrition and Human Health and Key Laboratory of Agro-ecology, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China; The Graduate School of the Chinese Academy of Sciences, Beijing 100039, China; Department of Animal Science and Faculty of Nutrition, Texas A&M University, College Station, TX 77843, USA.


Abstract

Obesity is a major health crisis worldwide and new treatments are needed to fight this epidemic. Using the swine model, we recently reported that dietary l-arginine (Arg) supplementation promotes muscle gain and reduces body-fat accretion. The present study tested the hypothesis that Arg regulates expression of key genes involved in lipid metabolism in skeletal muscle and white adipose tissue. Sixteen 110-day-old barrows were fed for 60 days a corn- and soybean-meal-based diet supplemented with 1.0% Arg or 2.05% l-alanine (isonitrogenous control). Blood samples, longissimus dorsi muscle and overlying subcutaneous adipose tissue were obtained from 170-day-old pigs for biochemical studies. Serum concentrations of leptin, alanine and glutamine were lower, but those for Arg and proline were higher in Arg-supplemented pigs than in control pigs. The percentage of oleic acid was higher but that of stearic acid and linoleic acid was lower in muscle of Arg-supplemented pigs, compared with control pigs. Dietary Arg supplementation increased mRNA levels for fatty acid synthase in muscle, while decreasing those for lipoprotein lipase, glucose transporter-4, and acetyl-coenzyme A carboxylase-alpha in adipose tissue. Additionally, mRNA levels for hormone sensitive lipase were higher in adipose tissue of Arg-supplemented pigs compared with control pigs. These results indicate that Arg differentially regulates expression of fat-metabolic genes in skeletal muscle and white adipose tissue, therefore favoring lipogenesis in muscle but lipolysis in adipose tissue. Our novel findings provide a biochemical basis for explaining the beneficial effect of Arg in improving the metabolic profile in mammals (including obese humans). Copyright © 2010 Elsevier Inc. All rights reserved.

PMID: 20619625 [PubMed - as supplied by publisher]

L-Arginine Regulates Fat Loss | Metabolic Alchemy
Right Hook is offline   Reply With Quote
Sponsored Links
Reply

Bookmarks

Tags
fat, larginine, loss, regulates


Similar Threads
Thread Thread Starter Forum Replies Last Post
L-Arginine lift3r Nutrition, Diet and Supplements 3 03-01-2012 03:29 PM
Exercise and Fat Loss BendtheBar General Fitness & Health 6 10-01-2011 10:21 AM
Workout for Fat Loss BendtheBar General Fitness & Health 27 07-07-2011 04:26 PM
The Difference Between Weight Loss vs. Fat Loss Dork McSchlorp General Board 0 06-03-2010 06:10 AM
Can arginine lower exercise fatigue? Jerry Brainum General Board 0 04-26-2010 09:30 PM

Thread Tools Search this Thread
Search this Thread:

Advanced Search
Display Modes

Posting Rules
You may not post new threads
You may not post replies
You may not post attachments
You may not edit your posts

BB code is On
Smilies are On
[IMG] code is On
HTML code is Off

Forum Jump


All times are GMT -5. The time now is 05:02 AM.


Powered by vBulletin® Version 3.8.5
Copyright ©2000 - 2014, vBulletin Solutions, Inc.