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Old 07-11-2013, 03:28 PM   #11
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I have no strong personal opinion, but I found this quote interesting.

Claim: Fish oil supplements increase prostate cancer risk | JunkScience.com

Quote:
Though Im skeptical of the link with prostate cancer (weak statistical results), the important part of this study is

the finding that:

The analysis, which combined the data from 20 studies, found no reduction in all-cause mortality, heart attacks or strokes.

which is the reason to buy these supplements in the first place.
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Old 07-11-2013, 03:30 PM   #12
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Just received a copy of the paper.. attached for members since she didn't say to not distribute it.
Attached Files
File Type: pdf Fatty acids and prostate cancer JNCI Brasky July 2013.pdf (420.6 KB, 404 views)
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Old 07-11-2013, 03:33 PM   #13
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I use examine.com for meta-analysis of most things:

Fish Oil - In-Depth Scientific Supplement Information | Examine.com

That will keep you guys busy for a few days...
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Old 07-11-2013, 03:45 PM   #14
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Holy cow.. that's a lot of reading lol..
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Old 07-11-2013, 04:31 PM   #15
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Quote:
Originally Posted by ndrwdslv View Post
Just received a copy of the paper.. attached for members since she didn't say to not distribute it.
Many thanks for this. Interesting stuff. From the Introduction:

Quote:
In 2011, after an additional 54 464 person-years of follow-up, we reported that vitamin E, in contrast with a placebo, increased prostate cancer risk by 17%
And from the conclusion (my emboldening):

Quote:
In conclusion, in this large, prospective study of plasma phospholipid
fatty acids and prostate cancer risk, contrary to our
expectations
, we found that long-chain ω-3 PUFA overall, and
DPA and DHA in particular, were associated with strong, linear
increases in prostate cancer risk. We note that this is not a novel
finding
because it has been reported previously in two other
prospective blood biomarker studies that have examined the
associations between long-chain ω-3 PUFA and prostate cancer
risk. Whereas a lack of coherent mechanism has led authors of
previous studies, including us, to consider these findings suspect,
their replication here strongly suggests that long-chain ω-3
PUFA do play a role in enhancing prostate tumorigenesis.
As has
been made evident from many other clinical trials of nutritional
supplements and cancer risk, the associations of nutrients with
chronic disease are complex and may affect diseases differently.
Long-chain ω-3 PUFA have been widely promoted for prevention
of heart disease and cancer. Both this study and a recent
meta-analysis of clinical trials showing no effects of long-chain
ω-3 PUFA supplementation on all-cause mortality, cardiac death,
myocardial infarction, or stroke (48) suggest that general recommendations
to increase long-chain ω-3 PUFA intake should consider
its potential risks.
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Old 07-11-2013, 04:37 PM   #16
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Quote:
Originally Posted by SCStrong View Post
It seems everything "may cause cancer" these days .... I am willing to bet, the good outweighs the bad on Omega 3's...IMHO



I agree. The media seem to pump this out all the time.

Last year I read chocolate can cause cancer, now you read it prevents it.


I wouldn't pay much attention to this stuff. I believe its often just fear mongering.

There's something every year...
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Old 07-11-2013, 04:39 PM   #17
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Quote:
Originally Posted by SCStrong View Post
It seems everything "may cause cancer" these days .... I am willing to bet, the good outweighs the bad on Omega 3's...IMHO
Everything causes cancer, including things supposed to prevent cancer.

I think you're right about the number of things causing cancer - if you take an enormous sample of people, you can get a statistically significant effect for many, many compounds. But some of these supplement studies are a bit more concerning than 'tomatoes cause cancer' scare stories, because many people are taking really quite large amounts of concentrated biologically active compounds.

I might take you up on that bet about omega 3s (at least when aggressively supplemented), though proving it one way or the other might be difficult .
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Old 07-11-2013, 04:50 PM   #18
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Quote:
Originally Posted by BendtheBar View Post
I use examine.com for meta-analysis of most things:

Fish Oil - In-Depth Scientific Supplement Information | Examine.com

That will keep you guys busy for a few days...
Yeah, I quite like that site. I've been using it a fair bit on my current supplement kick.
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Old 07-11-2013, 06:04 PM   #19
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Thanks for the discussion and information. This is why I posted the link here and not on other boards.
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