Originally Posted by ElementalVirago
Guys, correct me if I'm wrong but higher rep/lower weight doesn't necessarily make the muscle grow.
When a heavy enough weight is used for enough repetitions, chemical messages are sent to the cells to start protein synthesis. This doesn't have to be because of microtrauma, it just has to be enough of a stimulus to send the message. Microtrauma happens when you deplete the cells and the muscles become brittle. Therefore you need enough TUT to deplete. So, you need enough weight and enough reps to make it all happen. From what I can gather, this would be a rep range between 5 and 15 total reps per set. The weight would also have to be progressive for protein synthesis to stay ahead of protein breakdown. Therefore (I like that word) you'd have to constantly try to do more every workout.