Yes. Isolations provide a more direct method of building the mass of specific muscles (hence the term 'isolation').
Hypothetically, a workout can be constructed which is comprised solely of isolation exercises, but it would not be a very good one.
Overall muscle strength AND size is built most successfully by using compounds and stressing the Central Nervous System in ways that isolations just can't do.
A workout which incorporates both heavy compounds first and isolations second is a tested and proven training regimen.
W.A. AMATEUR STRONGMAN
Axle clean-press: 100 kgs (220 lbs)
Bench press: 135 kgs (298 lbs) - 1st PL meet 16th October 2011
Deadlift w/Barbell: 180 kgs (397 lbs)
Deadlift w/Hexbar: 225 kgs (496 lbs)
Farmers walk: 240 kgs (530 lbs), 50 feet
Front squat: 100 kgs (220 lbs)
Log clean-press: 100 kgs (220 lbs)
Strict OHP: 85 kgs (187 lbs) 3 reps
Tyre flip: 260 kgs (573 lbs), 100 feet
Last edited by Abaddon; 07-11-2011 at 08:32 AM.